Results 11 to 20 of about 201,089 (265)
Aminorex and the pulmonary circulation [PDF]
Thorax, 1971 Aminorex (2-amino-5-phenyl-2-oxazoline) is an appetite-suppressing drug which was available in Switzerland from November 1965 to October 1968. In 1967 a sudden 20-fold increase in the incidence of primary pulmonary hypertension was observed in a Swiss medical clinic.
J M, Kay, P, Smith, D, Heath
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Megakaryocytes in the Pulmonary Circulation [PDF]
Blood, 1963 Abstract The streptolysin 0 hemolysis method for isolation of cancer cells in the blood was employed for direct observations of the incidence and some characteristics of circulating megakaryocytes. In a series of 168 patients, circulating megakaryocytes were found in 77 per cent of the blood samples.
T M, SCHEININ, A P, KOIVUNIEMI
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Circular RNAs in pulmonary hypertension: Emerging biological concepts and potential mechanism
Animal Models and Experimental Medicine, 2022 Circular RNAs (circRNAs) are endogenous RNAs with a covalently closed single‐stranded transcript. They are a novel class of genomic regulators that are linked to many important development and disease processes and are being pursued as clinical and ...
Qian Wang +6 more
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Frontiers in Cell and Developmental Biology, 2022 Background We recently demonstrated that circGSAP was diminished in lung tissues from patients with pulmonary arterial hypertension and in hypoxia-induced pulmonary microvascular endothelial cells (PMECs).
Yuanyuan Sun +11 more
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Frontiers in Cardiovascular Medicine, 2022 ObjectiveWhether exercise-induced venous-to-systemic shunt (EIS) during cardiopulmonary exercise testing (CPET) has different manifestations or characteristics in idiopathic pulmonary arterial hypertension (IPAH) and chronic thromboembolic pulmonary ...
Shang Wang +15 more
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Fulvine and the pulmonary circulation [PDF]
Thorax, 1971 The pyrrolizidine alkaloid, fulvine, is now accepted as a major cause of veno-occlusive disease of the liver in the West Indies, where it is ingested as a decoction of the plant Crotalaria fulva in bush tea. Fulvine is similar in chemical structure to monocrotaline, which is known to cause pulmonary hypertension in rats.
J M, Kay +4 more
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Biology and function of pericytes in the vascular microcirculation
Animal Models and Experimental Medicine, 2023 Pericytes are the main cellular components of tiny arteries and capillaries. Studies have found that pericytes can undergo morphological contraction or relaxation under stimulation by cytokines, thus affecting the contraction and relaxation of ...
Yue Wu +12 more
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Frontiers in Immunology, 2023 Pulmonary fibrosis (PF) and pulmonary hypertension (PH) have common pathophysiological features, such as the significant remodeling of pulmonary parenchyma and vascular wall.
Hui Zhao +13 more
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BMC Cardiovascular Disorders, 2018 Background To study the oxygen uptake efficiency and determine usefulness of submaximal parameters of oxygen uptake in systemic lupus erythematosus associated pulmonary arterial hypertension (SLE PAH) on performing a cardiopulmonary exercise test (CPET).
Bigyan Pudasaini +13 more
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