Results 41 to 50 of about 211,135 (314)

Transition from Ambrisentan to Bosentan in Pulmonary Arterial Hypertension: A Single-Center Prospective Study

Canadian Respiratory Journal, 2018
Background and objective: Two endothelin receptor antagonists (ETRAs), bosentan and ambrisentan, are approved for patients with pulmonary arterial hypertension (PAH).
Su-Gang Gong, Lan Wang, Bigyan Pudasaini, Ping Yuan, Rong Jiang, Qin-Hua Zhao, Jing He, Rui Zhang, Wen-hui Wu, Jin-Ming Liu, Cai-cun Zhou   +10 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Phenotypic Analysis of Pulmonary Hypertension Associated With Low Diffusion Capacity and Preserved Lung Function

Pulmonary Circulation
Severe diffusion impairment in pulmonary arterial hypertension (PAH), particularly in idiopathic PAH (IPAH), has garnered considerable attention. However, comprehensive data on low diffusion capacity of the lungs for carbon monoxide (DLCO) with preserved
Qin‐Hua Zhao, Rui Zhang, Shao‐Fei Liu, Ci‐Jun Luo, Hong‐Ling Qiu, Wen‐Hui Wu, Hui‐Ting Li, Jing He, Ping Yuan, Jian Xu, Jin‐Ming Liu, Su‐Gang Gong, Lan Wang   +12 more
doaj   +1 more source

Chronic Thromboembolic Pulmonary Hypertension: Medical Treatment [PDF]

, 2013
Chronic thromboembolic pulmonary hypertension (CTEPH) is responsible for significant levels of morbidity and mortality. the estimated cumulative incidence of CTEPH is 2-4% among patients presenting with acute pulmonary thromboembolism.
Savas Ozsu, Halit Cınarka, Özsu, Savaş, Çınarka, Halit   +3 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

CircALMS1 Alleviates Pulmonary Microvascular Endothelial Cell Dysfunction in Pulmonary Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Circular RNAs can serve as regulators influencing the development of pulmonary hypertension (PH). However, their function in pulmonary vascular intimal injury remains undefined.
Xiaoyi Hu, Yuanyuan Sun, Shang Wang, Hui Zhao, Yaqin Wei, Jiaqi Fu, Yuxia Huang, Wenhui Wu, Jinling Li, Jinming Liu, Sugang Gong, Qinhua Zhao, Lan Wang, Rong Jiang, Xiao Song, Ping Yuan   +15 more
doaj   +1 more source

Prognostic Value of Gamma-Glutamyltransferase in Male Patients With Idiopathic Pulmonary Arterial Hypertension

Frontiers in Cardiovascular Medicine, 2020
Background: The elevated gamma-glutamyltransferase (GGT) activity is regarded as an indicator of cardiovascular disease, with males having higher values than females.
Gang-Hua Lu, Su-Gang Gong, Chao Li, Qin-Hua Zhao, Rong Jiang, Ci-Jun Luo, Lan Wang, Lan Wang, Rui Zhang, Rui Zhang   +9 more
doaj   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

An algorithm to identify cases of pulmonary arterial hypertension from the electronic medical record

Respiratory Research, 2022
Background Study of pulmonary arterial hypertension (PAH) in claims-based (CB) cohorts may facilitate understanding of disease epidemiology, however previous CB algorithms to identify PAH have had limited test characteristics.
Kyle P. Schuler, Anna R. Hemnes, Jeffrey Annis, Eric Farber-Eger, Brandon D. Lowery, Stephen J. Halliday, Evan L. Brittain   +6 more
doaj   +1 more source

A Preliminary Study on the Relationship Between High-Resolution Computed Tomography and Pulmonary Function in People at Risk of Developing Chronic Obstructive Pulmonary Disease

Frontiers in Medicine, 2022
ObjectivesPatients with chronic obstructive pulmonary disease (COPD) have high morbidity and mortality, the opportunity to carry out a thoracic high-resolution CT (HRCT) scan may increase the possibility to identify the group at risk of disease.
Rui Lv, Rui Lv, Mengyao Xie, Huaqian Jin, Pingping Shu, Mingli Ouyang, Yanmao Wang, Dan Yao, Lehe Yang, Xiaoying Huang, Yiran Wang   +10 more
doaj   +1 more source