Results 1 to 10 of about 37,784 (244)

PFKFB3 Inhibits Fructose Metabolism in Pulmonary Microvascular Endothelial Cells. [PDF]

Am J Respir Cell Mol Biol, 2023
Abstract Pulmonary microvascular endothelial cells contribute to the integrity of the lung gas exchange interface, and they are highly glycolytic. Although glucose and fructose represent discrete substrates available for glycolysis, pulmonary microvascular endothelial cells prefer glucose over fructose, and the mechanisms involved in ...
Lee JY, Stevens RP, Pastukh VV, Pastukh VM, Kozhukhar N, Alexeyev MF, Reisz JA, Nerguizian D, D'Alessandro A, Koloteva A, Gwin MS, Roberts JT, Borchert GM, Wagener BM, Pittet JF, Graham BB, Stenmark KR, Stevens T.   +17 more
europepmc   +6 more sources

Influenza A virus infects pulmonary microvascular endothelial cells leading to microvascular leakage and release of pro-inflammatory cytokines [PDF]

PeerJ, 2021
Objective To investigate the replication of influenza A virus A/Puerto Rico/8/34 (H1N1) in pulmonary microvascular endothelial cells and its effect on endothelial barrier function.
Tiantian Han, Yanni Lai, Yong Jiang, Xiaohong Liu, Danhua Li   +4 more
doaj   +3 more sources

Method for the Culture of Mouse Pulmonary Microvascular Endothelial Cells

Annals of Pulmonology, 2017
Pulmonary microvascular endothelial cells (ECs) are integral to the alveoli-capillary barrier of the lung. The EC barrier integrity is known to be disrupted in severe lung diseases such as acute respiratory distress syndrome (ARDS), pneumonia and pulmonary edema.
Verin Alexander D
exaly   +3 more sources

Endothelial Microparticles Derived from Primary Pulmonary Microvascular Endothelial Cells Mediate Lung Inflammation in Chronic Obstructive Pulmonary Disease by Transferring microRNA-126 [PDF]

Journal of Inflammation Research, 2022
Yiming Ma, Xue He, Xiangming Liu, Yingjiao Long, Yan Chen Department of Respiratory and Critical Care Medicine, The Second Xiangya Hospital of Central South University, Changsha, People’s Republic of ChinaCorrespondence: Yan Chen; Yingjiao Long, Email ...
Ma Y, He X, Liu X, Long Y, Chen Y
doaj   +2 more sources

Prohibitin Protects Pulmonary Microvascular Endothelial Cells Against Cigarette Smoke Extract-Induced Cell Apoptosis and Inflammation [PDF]

International Journal of COPD, 2022
Yating Peng,1– 3 Wei Cheng,1– 3 Jiaxi Duan,1– 3 Yiyang Zhao,1– 3 Zijing Zhou,1– 3 Aiyuan Zhou,1– 3 Minhua Deng,1– 4 Hong Peng,1– 3 Ruoyun Ouyang,1– 3 Yan Chen,1– 3 Ping Chen1– 3 1Department of Pulmonary and Critical Care Medicine, Second Xiang Ya ...
Peng Y, Cheng W, Duan J, Zhao Y, Zhou Z, Zhou A, Deng M, Peng H, Ouyang R, Chen Y, Chen P   +10 more
doaj   +2 more sources

LRG1 promotes the apoptosis of pulmonary microvascular endothelial cells through KLK10 in chronic obstructive pulmonary disease [PDF]

Tobacco Induced Diseases
Introduction Cigarette smoking is one of the most important causes of COPD and could induce the apoptosis of pulmonary microvascular endothelial cells (PMVECs). The conditional knockout of LRG1 from endothelial cells reduced emphysema in mice.
Wei Cheng, Qing Song, Aiyuan Zhou, Ling Lin, Yiyang Zhao, Jiaxi Duan, Zijing Zhou, Yating Peng, Cong Liu, Yuqin Zeng, Ping Chen   +10 more
doaj   +2 more sources

CircALMS1 Alleviates Pulmonary Microvascular Endothelial Cell Dysfunction in Pulmonary Hypertension

Journal of the American Heart Association
Background Circular RNAs can serve as regulators influencing the development of pulmonary hypertension (PH). However, their function in pulmonary vascular intimal injury remains undefined. Thus, we aimed to identify specifically expressed circular RNAs in pulmonary microvascular endothelial cells (PMECs) under hypoxia and PH.
Ping Yuan, Xiao Song, Su-Gang Gong
exaly   +4 more sources

Human pulmonary microvascular endothelial cells respond to DAMPs from injured renal tubular cells [PDF]

Pulmonary Circulation
Acute kidney injury (AKI) causes distant organ dysfunction through yet unknown mechanisms, leading to multiorgan failure and death. The lungs are one of the most common extrarenal organs affected by AKI, and combined lung and kidney injury has a ...
Sean E. DeWolf, Alana A. Hawkes, Sunil M. Kurian, Diana E. Gorial, Mark L. Hepokoski, Stephanie S. Almeida, Isabella R. Posner, Dianne B. McKay   +7 more
doaj   +2 more sources

Acod1/itaconate activates Nrf2 in pulmonary microvascular endothelial cells to protect against the obesity-induced pulmonary microvascular endotheliopathy. [PDF]

Respir Res
Abstract Background Obesity is the main risk factor leading to the development of various respiratory diseases, such as asthma and pulmonary hypertension. Pulmonary microvascular endothelial cells (PMVECs) play a significant role in the development of lung diseases.
Zhu L, Wu Z, Liu Y, Ming Y, Xie P, Jiang M, Qi Y.   +6 more
europepmc   +4 more sources

Baicalin Induces IFN-α/β and IFN-γ Expressions in Cultured Mouse Pulmonary Microvascular Endothelial Cells

Journal of Integrative Agriculture, 2012
We studied the effect of baicalin, an extract from Radix Scutellariae (a traditional Chinese medicine) in inducing mouse pulmonary microvascular endothelial cells (MPMVECs) to produce interferons (IFNs).
Ge HU, Jiu-zhou XUE, Jing LIU, Tao ZHANG, Hong DONG, Hui-qin DUAN, Zuo-jun YANG, Xiao-ming REN, Xiang MU   +8 more
doaj   +3 more sources