Results 31 to 40 of about 37,784 (244)
Pulmonary microvascular albumin leak is associated with endothelial cell death in murine sepsis-induced lung injury in vivo. [PDF]
PLoS ONE, 2014 Sepsis is a systemic inflammatory response that targets multiple components of the cardiovascular system including the microvasculature. Microvascular endothelial cells (MVEC) are central to normal microvascular function, including maintenance of the ...
Sean E Gill +4 more
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Journal of Nucleic Acids, 2011 Background. Adhesion molecules are known to influence postoperative organ function, they are hardly involved in the inflammatory response following the ischemia-reperfusion injury.
Tobias Walker +6 more
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Research progress on the effects of tight junction on lung permeability [PDF]
Jichu yixue yu linchuang, 2021 The alveolar epithelial barrier and the pulmonary microvascular endothelial barrier will be destroyed when the lung tissue is damaged, thus affecting the permeability of the lung and causing serious pulmonary edema.
WU Xie, YAN Fu-xia
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Human Herpesvirus-8 Infection of Primary Pulmonary Microvascular Endothelial Cells [PDF]
American Journal of Respiratory Cell and Molecular Biology, 2008 Abstract Human herpesvirus-8 (HHV-8) is the causative agent of Kaposi's sarcoma and is associated with the angioproliferative disorders primary effusion lymphoma and multicentric Castleman's disease. Evidence of HHV-8 infection within the pulmonary vasculature of patients with idiopathic pulmonary arterial hypertension (IPAH) has been
Todd M, Bull +7 more
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Endothelium Infection and Dysregulation by SARS-CoV-2: Evidence and Caveats in COVID-19
Viruses, 2020 The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by the acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) poses a persistent threat to global public health.
Isabelle Bernard +3 more
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The Role of PGE2 in Alveolar Epithelial and Lung Microvascular Endothelial Crosstalk
Scientific Reports, 2017 Disruption of the blood-air barrier, which is formed by lung microvascular endothelial and alveolar epithelial cells, is a hallmark of acute lung injury. It was shown that alveolar epithelial cells release an unidentified soluble factor that enhances the
Thomas Bärnthaler +15 more
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Respiratory Research, 2018 Background Endothelial barrier dysfunction is central to the pathogenesis of sepsis-associated acute lung injury (ALI). Microtubule (MT) dynamics in vascular endothelium are crucial for the regulation of endothelial barrier function.
Shengtian Mu +6 more
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Rac2 in murine pulmonary microvascular endothelial cells (ECs)
The FASEB Journal, 2010 Rac2 is a small GTPase in the Rho family. The lungs of uninjured Rac2−/− mice show enhanced plasma flux. This study determined if Rac2 is expressed and regulates phosphorylation of cytoskeletal proteins in ECs. Real time PCR showed that ECs isolated from murine lung digests by negative selection of CD45+ cells (
John Clifford Gomez, Claire M. Doerschuk
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The role of endothelial MERTK during the inflammatory response in lungs.
PLoS ONE, 2019 As a key homeostasis regulator in mammals, the MERTK receptor tyrosine kinase is crucial for efferocytosis, a process that requires remodeling of the cell membrane and adjacent actin cytoskeleton.
Yitong Li +6 more
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CD40 activation is angioproliferative in pulmonary microvascular endothelial cells
The FASEB Journal, 2009 Introduction Endothelial CD40 is important during inflammation as an angiogenic stimulus. We tested whether CD40 expression in PMVEC is associated with angioproliferative potential. Methods Western analysis for CD40 expression was ...
Jeffrey T Baker, Timothy M Moore
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