N,N,N-Trimethyl chitosan as a permeation enhancer for inhalation drug delivery: interaction with a model pulmonary surfactant [PDF]
, 2023 N,N,N-Trimethyl chitosan (TMC), a biocompatible and biodegradable derivative of chitosan, is currently used as a permeation enhancer to increase the translocation of drugs to the bloodstream in the lungs. This article discusses the effect of TMC on a mimetic pulmonary surfactant, Curosurf, a low-viscosity lipid formulation administered to preterm ...
arxiv +1 more source
Fibro-CoSANet: Pulmonary Fibrosis Prognosis Prediction using a Convolutional Self Attention Network [PDF]
, 2021 Idiopathic pulmonary fibrosis (IPF) is a restrictive interstitial lung disease that causes lung function decline by lung tissue scarring. Although lung function decline is assessed by the forced vital capacity (FVC), determining the accurate progression of IPF remains a challenge. To address this challenge, we proposed Fibro-CoSANet, a novel end-to-end
arxiv +1 more source
The inspiratory capacity/total lung capacity ratio as a predictor of survival in an emphysematous phenotype of chronic obstructive pulmonary disease. [PDF]
, 2015 BackgroundForced expiratory volume in 1 second (FEV1) grades severity of COPD and predicts survival. We hypothesize that the inspiratory capacity/total lung capacity (IC/TLC) ratio, a sensitive measure of static lung hyperinflation, may have a ...
Balfe, David +4 more
core +1 more source
HIV infection is an independent risk factor for decreased 6-minute walk test distance. [PDF]
, 2019 BackgroundAmbulatory function predicts morbidity and mortality and may be influenced by cardiopulmonary dysfunction. Persons living with HIV (PLWH) suffer from a high prevalence of cardiac and pulmonary comorbidities that may contribute to higher risk of
Chandra, Divay +11 more
core +2 more sources
Lung Imaging with UTE MRI [PDF]
, 2023 Cross-sectional imaging of the lungs, or pulmonary imaging, has proven to be an incredibly valuable tool in a wide range of pulmonary diseases. The vast majority of lung imaging is done with CT, as it is fast enough to freeze respiratory motion and provides high spatial resolution to visualize fine structure of the lungs.
arxiv +1 more source
Clinical and radiographic features of sarcoidosis in menopausal women: The impact on therapeutic approach and prognosis [PDF]
Vojnosanitetski Pregled, 2010 Background/Aim. Sarcoidosis is a multisystemic granulomatous disease of unknown etiology. The aim of the study was to determine are there significant differences in clinical manifestations, radiographic and lung function findings and therapeutic approach
Milošković Vladana R. +1 more
doaj +1 more source
Journal of Respiration, 2023 Tuberculosis-related lung damage is very different. Lung ventilation disorders have been studied in patients with pulmonary tuberculosis (TB) during the active process and after treatment, but the main causes of gas exchange changes have not been ...
Larisa D. Kiryukhina +5 more
doaj +1 more source
Amiodarone-Induced Pulmonary Toxicity - A Frequently Missed Complication. [PDF]
, 2016 IntroductionAmiodarone is often used in the suppression of tachyarrhythmias. One of the more serious adverse effects includes amiodarone pulmonary toxicity (APT).
Dang, Natasha +4 more
core +2 more sources
Frontiers in Pediatrics, 2021 Pulmonary complications in adults who recovered from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported even in minimally symptomatic patients.
Ilaria Bottino +16 more
doaj +1 more source
Quantitative CT analysis in patients with pulmonary emphysema: is lung function influenced by concomitant unspecific pulmonary fibrosis? [PDF]
, 2019 Purpose: Quantitative analysis of CT scans has proven to be a reproducible technique, which might help to understand the pathophysiology of chronic obstructive pulmonary disease (COPD) and combined pulmonary fibrosis and emphysema.
Doellinger, Felix +5 more
core +1 more source