Results 71 to 80 of about 30,235 (338)

Quantitative Observations On The Pulmonary Anatomy Of The Domestic Fowl And Other Ground-Dwelling Birds [PDF]

, 1987
The pulmonary stereology of the adult domestic fowl (Gallus gallus variant domesticus) , the Red Jungle Fowl (Gallus gallus) , the Muscovy Duck (Cairina moschata) , the White-breasted Water-Hen (Amaurornis phoenicurus), and the juveniles of the ...
M. K. Vidyadaran,
core  

Pulmonary artery stiffness in chronic obstructive pulmonary disease (copd) and emphysema: The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study [PDF]

, 2018
Purpose: Chronic obstructive pulmonary disease (COPD) and particularly emphysema are characterized by stiffness of the aorta, due in part to accelerated elastin degradation in the lungs and aorta. Stiffness of the pulmonary arteries (PAs) may also be
Balte, Pallavi, Barr, R. Graham, Bluemke, David A., Carr, James, Dashnaw, Stephen, Gomes, Antoinette S., Hoffman, Eric A., Kawut, Steven M., Lima, Joao A.C., Liu, Chia-Ying, McAllister, David A., Parikh, Megha, Poor, Hooman D.   +12 more
core   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

The effects of interventional mitral valve repair using the MitraClip System on the results of pulmonary function testing, pulmonary pressure and diffusing capacity of the lung

BMC Cardiovascular Disorders, 2021
Background The study analyzes changes in lung function, pulmonary pressure and diffusing capacity of the lung in patients with mitral valve regurgitation (MR) treated by MitraClip implantation.
Lucie Kretzler, Stephan Große, Stephan Wiedemann, Carsten Wunderlich, Chris Nowak, Christian Riedel, Tomáš Sieger, Steffen Schoen   +7 more
doaj   +1 more source

Endothelial-to-mesenchymal transition: a precursor to pulmonary arterial remodelling in patients with idiopathic pulmonary fibrosis

ERJ Open Research, 2023
Background We have previously reported arterial remodelling in patients with idiopathic pulmonary fibrosis (IPF) and suggested that endothelial-to-mesenchymal transition (EndMT) might be central to these changes.
Archana Vijay Gaikwad, Wenying Lu, Surajit Dey, Prem Bhattarai, Greg Haug, Josie Larby, Collin Chia, Jade Jaffar, Glen Westall, Gurpreet Kaur Singhera, Tillie-Louise Hackett, Mathew Suji Eapen, Sukhwinder Singh Sohal   +12 more
doaj   +1 more source

Possible role of Krüppel-like factor 5 in the remodeling of small airways and pulmonary vessels in chronic obstructive pulmonary disease [PDF]

, 2016
BACKGROUND: Small airway remodeling is an important cause of the airflow limitation in chronic obstructive pulmonary disease (COPD). A large population of patients with COPD also have pulmonary hypertension.
Abe, K, Hashimoto, Y, Ichikawa, T, Ichinose, M, Kikuchi, T, Koarai, A, Numakura, T, Okazaki, T, Onodera, K, Sato, K, Sugiura, H, Tamada, T, Tanaka, R, Yamada, M, Yanagisawa, S   +14 more
core   +2 more sources

Pulmonary diffusing capacity in chronic dialysis patients

Respiratory Medicine, 2002
Patients with end-stage renal disease treated by hemodialysis with bioincompatible membranes are exposed during the dialysis period to acute effects on lung microcirculation, which may result in pulmonary fibrosis and diffusion defects in long-standing dialysis.
F. Coronel, José Luis Álvarez-Sala, J.M.F. Sánchez-Alarcos, J. A. Herrero, C. Moratilla, A. Barrientos, C. Gámez   +6 more
openaire   +3 more sources

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

Acute Moderate-Intensity Aerobic Exercise under High PM_2.5 Levels Does Not Influence the Pulmonary Function and Lung Diffusion Capacity in Healthy Young Men

Applied Sciences, 2022
Exposure to fine particulate matter (PM2.5) impairs the respiratory system and increases the morbidity and mortality of respiratory diseases. Even though aerobic exercise is known to improve pulmonary function in diverse populations, it can lead to an ...
Jin-Su Kim, Do Gyun Lee, Lin Wang, Heechan Kang, Moon-Hyon Hwang   +4 more
doaj   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source