Results 81 to 90 of about 148,678 (360)

Relationship between diffusion capacity and small airway abnormality in COPDGene. [PDF]

, 2019
Impaired single breath carbon monoxide diffusing capacity (DLCO) is associated with emphysema. Small airways disease (SAD) may be a precursor lesion to emphysema, but the relationship between SAD and DLCO is undescribed. We hypothesized that in mild COPD,
Casaburi, Richard, Criner, Rachel N, Curtis, Jeffrey L, Galbán, Craig J, Han, Mei Lan K, Hatt, Charles R, Kazerooni, Ella A, Labaki, Wassim W, Lynch, David A, MacIntyre, Neil R, Make, Barry J, Martinez, Fernando J, McCormack, Meredith C   +12 more
core   +1 more source

Fluorinated Graphene‐Coated N95 Respirators for Enhanced Protection against Viral Accumulation and Transmission

Advanced Engineering Materials, EarlyView.
We develop a one‐step spray coating approach to coat the fluorinated graphene (FG) nanosheet onto the N95 respirators. The spray‐coated superhydrophobic N95 respirators can effectively repel respiratory droplets off instantaneously and prevent SARS‐CoV‐2 virus accumulation on the surface.
Fengjie He, Jiongyu Zhang, Shengjie Zhai, Changchun Liu, Hui Zhao   +4 more
wiley   +1 more source

Pulmonary 99mTc-HMDP uptake correlates with restrictive ventilatory defects and abnormal lung reactance in transthyretin cardiac amyloidosis patients

Respiratory Research, 2022
Background Pulmonary involvement in individuals with transthyretin cardiac amyloidosis is unclear. The aim of this study was to quantify 99mTc-hydroxy methylene diphosphonate (HMDP) lung retention in hereditary transthyretin (ATTRv) cardiac amyloidosis ...
Astrid Monfort, Alexia Rivas, Rishika Banydeen, Jocelyn Inamo, Karim Farid, Remi Neviere   +5 more
doaj   +1 more source

Hierarchical stratification of the factors related to exertional dyspnoea and exercise intolerance in male COPD patients

Annals of Medicine, 2022
Background The order and extent of interactions across the factors affecting exertional dyspnoea (ED) and exercise intolerance (EI) in patients with chronic obstructive pulmonary disease (COPD) are not clear.
Ming-Lung Chuang
doaj   +1 more source

A Novel Protein‐Polysaccharide Oral Nanoemulsion Targeting Activated Hepatic Stellate Cells to Enhance the Therapeutic Effect of Pirfenidone on Fibrosis After Transarterial Chemoembolization for Liver Cancer

Advanced Functional Materials, EarlyView.
Transarterial Chemoembolization (TACE) may aggravate liver fibrosis. In this study, a novel oral targeting nanoemulsion is fabricated to enhance the therapeutic effect of antifibrotic drug‐pirfenidone (PFD) on fibrosis after TACE. Studies have shown that PFD nanoemulsion can enhance the oral liver targeting effect of PFD, and effectively improve the ...
Zhimei Cheng, Shan Xu, Yi Lei, Huizhou He, Runbin Sun, Xingle Jin, Cheneryu Huang, Yuhao Zheng, Jianqing Peng, Lei Tang, Peng Luo, Yi Chen, Shuai Zhang   +12 more
wiley   +1 more source

Mavrilimumab, a fully human granulocyte-macrophage colony-stimulating factor receptor α monoclonal antibody: long-term safety and efficacy in patients with rheumatoid arthritis [PDF]

, 2018
Objective: Mavrilimumab, a human monoclonal antibody, targets granulocyte-macrophage colony-stimulating factor receptor alpha. We report mavrilimumab long-term safety and efficacy in rheumatoid arthritis patients in two phase IIb studies (1071, 1107 ...
Achuthan, Akagawa, Aletaha, Aletaha, Antoniu, Avci, Berghen, Borg, Borie, Brown, Buch, Burmester, Burmester, Calisto, Cella, Chen, Cook, Cornish, Cottin, Crotti, Dawson, Felson, Fleetwood, Fries, Greven, Guo, Hamilton, Jaguin, Kelly, Khan, Lazaro, Listing, Minter, Prevoo, Shaw, Shibata, Singh, Tsuchiya, Van der Heijde, Van Gestel, Van Onna, Ware, Weinblatt, Yoshida, Zhan   +44 more
core   +1 more source

Endothelial-to-mesenchymal transition: a precursor to pulmonary arterial remodelling in patients with idiopathic pulmonary fibrosis

ERJ Open Research, 2023
Background We have previously reported arterial remodelling in patients with idiopathic pulmonary fibrosis (IPF) and suggested that endothelial-to-mesenchymal transition (EndMT) might be central to these changes.
Archana Vijay Gaikwad, Wenying Lu, Surajit Dey, Prem Bhattarai, Greg Haug, Josie Larby, Collin Chia, Jade Jaffar, Glen Westall, Gurpreet Kaur Singhera, Tillie-Louise Hackett, Mathew Suji Eapen, Sukhwinder Singh Sohal   +12 more
doaj   +1 more source

Pulmonary diffusing capacity in chronic dialysis patients

Respiratory Medicine, 2002
Patients with end-stage renal disease treated by hemodialysis with bioincompatible membranes are exposed during the dialysis period to acute effects on lung microcirculation, which may result in pulmonary fibrosis and diffusion defects in long-standing dialysis.
F. Coronel, José Luis Álvarez-Sala, J.M.F. Sánchez-Alarcos, J. A. Herrero, C. Moratilla, A. Barrientos, C. Gámez   +6 more
openaire   +3 more sources

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

Advanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im, Han‐Gil Jeong, Donghee Kim, Jimin Song, Ngoc Man Phan, Eun‐seo Choi, Young‐Min Kim, Seo‐Hyeon Jeong, Jooho Park, Inwon Park, Jaeyun Kim   +10 more
wiley   +1 more source

Acute Moderate-Intensity Aerobic Exercise under High PM_2.5 Levels Does Not Influence the Pulmonary Function and Lung Diffusion Capacity in Healthy Young Men

Applied Sciences, 2022
Exposure to fine particulate matter (PM2.5) impairs the respiratory system and increases the morbidity and mortality of respiratory diseases. Even though aerobic exercise is known to improve pulmonary function in diverse populations, it can lead to an ...
Jin-Su Kim, Do Gyun Lee, Lin Wang, Heechan Kang, Moon-Hyon Hwang   +4 more
doaj   +1 more source