Results 41 to 50 of about 10,951,042 (362)
Chronic Thromboembolic Pulmonary Hypertension: A Review of the Multifaceted Pathobiology
Biomedicines, 2023 Chronic thromboembolic pulmonary disease results from the incomplete resolution of thrombi, leading to fibrotic obstructions. These vascular obstructions and additional microvasculopathy may lead to chronic thromboembolic pulmonary hypertension (CTEPH ...
Hakim Ghani, Joanna Pepke-Zaba
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Life Sciences, 2019 Toll-like receptors (TLRs) comprise a clan of proteins involved in identification and triggering a suitable response against pathogenic attacks. As lung is steadily exposed to multiple infectious agents, antigens and host-derived danger signals, the inhabiting stromal and myeloid cells of the lung express an aggregate of TLRs which perceive the ...
Shweta Arora +10 more
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The patient experience of pulmonary hypertension: a large cross-sectional study of UK patients
BMC Pulmonary Medicine, 2019 Background Pulmonary Hypertension Association UK (PHA-UK) is the only charity in the UK especially for people affected by pulmonary hypertension (PH).
Iain Armstrong +6 more
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Respiratory Research, 2022 Background Trimethylamine N-oxide (TMAO), the gut microbiota-dependent metabolite, is a potential biomarker in several cardiovascular diseases. However, no study has investigated its value in pulmonary hypertension (PH).
Yicheng Yang +10 more
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Autophagy in Pulmonary Diseases [PDF]
American Journal of Respiratory and Critical Care Medicine, 2016 The pathogenesis of pulmonary diseases is often complex and characterized by multiple cellular events, including inflammation, cell death, and cell proliferation. The mechanisms by which these events are regulated in pulmonary diseases remain poorly understood.
Augustine M.K. Choi +2 more
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Protein engineering to develop a redox insensitive endothelial nitric oxide synthase
Redox Biology, 2014 The zinc tetrathiolate (ZnS4) cluster is an important structural feature of endothelial nitric oxide synthase (eNOS). The cluster is located on the dimeric interface and four cysteine residues (C94 and C99 from two adjacent subunits) form a cluster with ...
Ruslan Rafikov +9 more
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Iron pill aspiration syndrome: A case report and literature review
Respiratory Medicine Case Reports, 2023 Aspiration of iron pill containing ferrous sulfate into the airway can induce fulminant chemical burn and necrosis of the airway mucosa. Acute chemical burn and inflammatory response can result in life-threatening airway compromise. It can also result in
Y.R. Sedhai +8 more
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Cellular senescence mediates fibrotic pulmonary disease
Nature Communications, 2017 Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by interstitial remodelling, leading to compromised lung function. Cellular senescence markers are detectable within IPF lung tissue and senescent cell deletion rejuvenates pulmonary ...
M. Schafer +22 more
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Journal of British Surgery, 1944 Summary Part I: Pathology. 1. The life-cycle of the parasite and the anatomy of hydatid cyst are described. The incidence of hydatid disease in this country is reviewed. 2. The pathological changes peculiar to pulmonary hydatid disease are recorded.
Dillwyn Thomas, N. R. Barrett
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ERJ Open Research, 2021 Pulmonary hypertension (PH) is a life-shortening condition characterised by episodes of decompensation precipitated by factors such as disease progression, arrhythmias and sepsis. Surgery and pregnancy also place additional strain on the right ventricle.
Kris Bauchmuller +11 more
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