Results 71 to 80 of about 11,167,208 (428)

Telehealthcare for chronic obstructive pulmonary disease [PDF]

, 2011
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a disease of irreversible airways obstruction in which patients often suffer exacerbations. Sometimes these exacerbations need hospital care: telehealthcare has the potential to reduce admission
Car, Josip, Liu, Joseph L. Y., McLean, Susannah, Nurmatov, Ulugbek, Pagliari, Claudia, Sheikh, Aziz   +5 more
core   +2 more sources

Cellular senescence mediates fibrotic pulmonary disease

Nature Communications, 2017
Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by interstitial remodelling, leading to compromised lung function. Cellular senescence markers are detectable within IPF lung tissue and senescent cell deletion rejuvenates pulmonary ...
M. Schafer, T. White, K. Iijima, A. Haak, G. Ligresti, E. Atkinson, A. Oberg, J. Birch, Hanna Salmonowicz, Yi Zhu, Daniel L. Mazula, R. W. Brooks, Heike Fuhrmann-Stroissnigg, T. Pirtskhalava, Y. Prakash, T. Tchkonia, P. Robbins, M. Aubry, J. Passos, J. Kirkland, D. Tschumperlin, H. Kita, N. LeBrasseur   +22 more
semanticscholar   +1 more source

Susceptibility to exacerbation in chronic obstructive pulmonary disease.

New England Journal of Medicine, 2010
BACKGROUND Although we know that exacerbations are key events in chronic obstructive pulmonary disease (COPD), our understanding of their frequency, determinants, and effects is incomplete.
J. Hurst, J. Vestbo, A. Anzueto, N. Locantore, H. Müllerová, R. Tal-Singer, B. Miller, D. Lomas, A. Agustí, W. Macnee, P. Calverley, S. Rennard, E. Wouters, J. Wedzicha   +13 more
semanticscholar   +1 more source

Extraction of Pulmonary Airway in CT Scans Using Deep Fully Convolutional Networks [PDF]

arXiv, 2022
Accurate, automatic and complete extraction of pulmonary airway in medical images plays an important role in analyzing thoracic CT volumes such as lung cancer detection, chronic obstructive pulmonary disease (COPD), and bronchoscopic-assisted surgery navigation.
arxiv  

Implementing integrated care guidelines in asthma and COPD: It ain't easy!

Heliyon, 2023
Objective: To evaluate the implementation of a guideline-based, integrated, standardised, personal approach in patients with Chronic Obstructive Pulmonary Disease (COPD) or Asthma in a real-life situation.
Jan A. Witte, Erwin Birnie, Gert-Jan Braunstahl, Edmée van den Akker, Walter J.M. van Litsenburg, Niels H. Chavannes, Maureen P.M.H. Rutten - van Mölken, Johannes C.C.M. In ’t Veen   +7 more
doaj  

British Thoracic Society Guideline for the management of non-tuberculous mycobacterial pulmonary disease (NTM-PD)

BMJ Open Respiratory Research, 2017
The full guideline for the management of non-tuberculous mycobacterial pulmonary disease is published in Thorax. The following is a summary of the recommendations and good practice points.
C. Haworth, J. Banks, T. Capstick, A. Fisher, T. Gorsuch, I. Laurenson, A. Leitch, M. Loebinger, H. Milburn, Mark Nightingale, P. Ormerod, D. Shingadia, David Smith, N. Whitehead, R. Wilson, R. A. Floto   +15 more
semanticscholar   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

FEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung, Mikhail G. Dozmorov, SuJeong Song, Theingi Aung, Min Hee Park, Patricia J. Sime, Wook‐Jin Chae   +6 more
wiley   +1 more source

Idiopathic pulmonary arterial hypertension and co-existing lung disease: is this a new phenotype?

Pulmonary Circulation, 2020
Patients classified as idiopathic pulmonary arterial hypertension (defined as Group 1 on European Respiratory Society (ERS)/European Cardiac Society (ESC) criteria) may have evidence of minor co-existing lung disease on thoracic computed tomography.
Andrew J. Peacock, Yi Ling, Martin K. Johnson, David G. Kiely, Robin Condliffe, Charlie A. Elliot, J. Simon R. Gibbs, Luke S. Howard, Joanna Pepke-Zaba, Karen K.K. Sheares, Paul A. Corris, Andrew J. Fisher, James L. Lordan, Sean Gaine, J. Gerry Coghlan, S. John Wort, Michael A. Gatzoulis   +16 more
doaj   +1 more source

Real-World Effectiveness of Inhalation Therapy Among Patients With Symptomatic COPD in China: A Multicenter Prospective Study

Frontiers in Pharmacology, 2021
Purpose: This real-world study evaluated the effectiveness of different inhalation therapies in patients with symptomatic chronic obstructive pulmonary disease (COPD) in China and also explored the relevant factors that influence the effectiveness of ...
Wei Cheng, Jiaxi Duan, Aiyuan Zhou, Yiyang Zhao, Rong Yi, Yi Liu, Dingding Deng, Xin Li, Yuqin Zeng, Yating Peng, Qing Song, Ling Lin, Min Yang, Ping Chen   +13 more
doaj   +1 more source

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Nature Genetics, 2018
Reduced lung function predicts mortality and is key to the diagnosis of chronic obstructive pulmonary disease (COPD). In a genome-wide association study in 400,102 individuals of European ancestry, we define 279 lung function signals, 139 of which are ...
N. Shrine, A. Guyatt, A. Erzurumluoglu, V. Jackson, B. Hobbs, C. Melbourne, C. Batini, K. Fawcett, Kijoung Song, P. Sakornsakolpat, Xingnan Li, Ruth Boxall, N. Reeve, M. Obeidat, J. Zhao, M. Wielscher, S. Weiss, K. Kentistou, J. Cook, B. Sun, Jian Zhou, J. Hui, S. Karrasch, M. Imboden, S. Harris, J. Marten, Stefan Enroth, S. Kerr, I. Surakka, V. Vitart, T. Lehtimäki, R. Allen, P. Bakke, T. Beaty, E. Bleecker, Y. Bossé, C. Brandsma, Zhengming Chen, J. Crapo, J. Danesh, D. Demeo, F. Dudbridge, R. Ewert, C. Gieger, A. Gulsvik, A. Hansell, K. Hao, Joshua D Hoffman, J. Hokanson, G. Homuth, Peter K. Joshi, P. Joubert, C. Langenberg, Xuan Li, Liming Li, Kuang Lin, L. Lind, N. Locantore, J. Luan, A. Mahajan, J. Maranville, A. Murray, D. Nickle, R. Packer, M. Parker, Megan L. Paynton, D. Porteous, Dmitry Prokopenko, D. Qiao, R. Rawal, H. Runz, I. Sayers, D. Sin, Blair H. Smith, M. Soler Artigas, D. Sparrow, R. Tal-Singer, P. Timmers, M. van den Berge, J. Whittaker, P. Woodruff, L. Yerges-Armstrong, O. Troyanskaya, O. Raitakari, M. Kähönen, O. Polašek, U. Gyllensten, I. Rudan, I. Deary, N. Probst-Hensch, H. Schulz, A. James, James F. Wilson, B. Stubbe, E. Zeggini, M. Jarvelin, N. Wareham, E. Silverman, C. Hayward, A. Morris, A. Butterworth, R. Scott, R. Walters, D. Meyers, M. Cho, D. Strachan, I. Hall, M. Tobin, L. Wain   +108 more
semanticscholar   +1 more source