Results 81 to 90 of about 1,301,573 (319)

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Pulmonary epithelium, cigarette smoke, and chronic obstructive pulmonary disease [PDF]

, 2007
Chronic obstructive pulmonary disease (COPD) is a complex chronic inflammatory disease involving a wide variety of cells and inflammatory mediators. The most important etiological factor in the development of this disease is cigarette smoking.
Tetley, TD, Thorley, AJ
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Correlating changes in lung function with patient outcomes in chronic obstructive pulmonary disease: a pooled analysis.

, 2011
Background Relationships between improvements in lung function and other clinical outcomes in chronic obstructive pulmonary disease (COPD) are not documented extensively.
Pinault, Gregory, Nedelman Jerry, Jones, Paul W, James F Donohue, Jones, PW, Donohue, JF, Steve Pascoe, Pinault Gregory, Pascoe Steve, Donohue James F, Lassen Cheryl, Pinault, G, Pascoe, S, Nedelman, J, Pascoe, Steve, Jerry Nedelman, Paul W Jones, Lassen, Cheryl, Jones Paul W, Cheryl Lassen, Gregory Pinault, Nedelman, Jerry, Donohue, James F, Lassen, C   +23 more
core   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Diffusing capacity of the lung for carbon monoxide, transfer coefficient of the lung for carbon monoxide and forced vital capacity/diffusing capacity of the lung for carbon monoxide in suspected systemic sclerosis-associated pulmonary hypertension: insights from the ASPIRE registry

ERJ Open Research
Objectives There are limited data comparing parameters reflecting gas transfer used to assess the likelihood of pulmonary hypertension (PH) in patients with systemic sclerosis (SSc) and regarding the impact of transitioning to Global Lung Initiative (GLI)
Howard Smith, A.A. Roger Thompson, Mohammed Akil, Samer Alabed, Catherine Billings, Athanasios Charalampopoulos, Krit Dwivedi, Charlie A. Elliot, Abdul Hameed, Ashraful Haque, Neil Hamilton, Catherine Hill, Judith Hurdman, Rachael Kilding, Kar-Ping Kuet, Smitha Rajaram, Alexander M.K. Rothman, Ian Smith, Andrew J. Swift, David G. Kiely, Robin Condliffe   +20 more
doaj   +1 more source

Breathing and Breathlessness: Chronic Obstructive Pulmonary Disease in Uruguay [PDF]

, 2013
An increasingly common part of being human is living with chronic health problems for which management over time, and not cure, is the goal of medical treatment.
Wainwright, M., WAINWRIGHT, MEGAN,JULIE
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Estimating the cost-effectiveness of fluticasone propionate for treating chronic obstructive pulmonary disease in the presence of missing data [PDF]

, 2006
Objectives: To explore the cost-effectiveness of fluticasone propionate (FP) for the treatment of chronic obstructive pulmonary disease (COPD), we estimated costs and qualityadjusted life-years (QALYs) over 3 years, based on an economic appraisal of a ...
Spencer, Michael D., Spencer, S, Spencer, Sally, Spencer, M.D., Lozano-Ortega, Greta, Briggs, AH, Briggs, A.H., Burge, P Sherwood, Bale, G., Burge, PS, Burge, P. Sherwood, Spencer, MD, Briggs, Andrew H., Briggs, Andrew H, Spencer, Michael D, Lozano-Ortega, G., Sherwood, P, Burge, S., Bale, G, Lozano-Ortega, G, Spencer, S., Bale, Geraldine, Spencer, Sally; id_orcid   +22 more
core   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Association between serum lysyl oxidase-like 2 and chitinase-3-like protein 1 levels and Mycobacterium tuberculosis drug resistance in children with pulmonary tuberculosis

BMC Pediatrics
Objective To investigate whether serum lysyl oxidase-like 2 (LOXL2) and chitinase-3-like protein 1 (YKL-40) levels are associated with drug-resistant Mycobacterium tuberculosis in children with pulmonary tuberculosis.
Qian Zhai, Xianglong Kong, Qian Li, Na Yang   +3 more
doaj   +1 more source

Systematic review on inhaled corticosteroid monotherapy and its efficacy and safety in longterm treatment of patients with chronic obstructive pulmonary disease (COPD) [PDF]

--chronic obstructive pulmonary disease,COPD,corticosteroids,systematic review,chronisch obstruktive Lungenerkrankung,COPD,Kortikosteroid,systematischer ...
Wasem, Jürgen, Kossmann, Beate, Niebuhr, Dea, Buchberger, Barbara, Neumann, Anja   +4 more
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