Results 71 to 80 of about 1,149,004 (269)

Diffusing capacity of the lung for carbon monoxide, transfer coefficient of the lung for carbon monoxide and forced vital capacity/diffusing capacity of the lung for carbon monoxide in suspected systemic sclerosis-associated pulmonary hypertension: insights from the ASPIRE registry

ERJ Open Research
Objectives There are limited data comparing parameters reflecting gas transfer used to assess the likelihood of pulmonary hypertension (PH) in patients with systemic sclerosis (SSc) and regarding the impact of transitioning to Global Lung Initiative (GLI)
Howard Smith, A.A. Roger Thompson, Mohammed Akil, Samer Alabed, Catherine Billings, Athanasios Charalampopoulos, Krit Dwivedi, Charlie A. Elliot, Abdul Hameed, Ashraful Haque, Neil Hamilton, Catherine Hill, Judith Hurdman, Rachael Kilding, Kar-Ping Kuet, Smitha Rajaram, Alexander M.K. Rothman, Ian Smith, Andrew J. Swift, David G. Kiely, Robin Condliffe   +20 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Association between serum lysyl oxidase-like 2 and chitinase-3-like protein 1 levels and Mycobacterium tuberculosis drug resistance in children with pulmonary tuberculosis

BMC Pediatrics
Objective To investigate whether serum lysyl oxidase-like 2 (LOXL2) and chitinase-3-like protein 1 (YKL-40) levels are associated with drug-resistant Mycobacterium tuberculosis in children with pulmonary tuberculosis.
Qian Zhai, Xianglong Kong, Qian Li, Na Yang   +3 more
doaj   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Case report: A finding of PVOD and PAH in first degree relatives suggests shared heritable risk and overlapping features of both pulmonary vascular diseases

Respirology Case Reports
Pulmonary veno‐occlusive disease (PVOD) is a rare form of pulmonary vascular disease that is difficult to distinguish clinically from pulmonary arterial hypertension (PAH).
Roger Winters, Lindsay M. Forbes, Dunbar Ivy, Carlyne Cool, Bryan D. Park, Peter Hountras, David Badesch, Sue Gu, Edda Spiekerkoetter, Roham Zamanian, Stacey LeierGluck, Todd M. Bull   +11 more
doaj   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

A Trial of Home Oxygen for Acute Asthma Attacks for the Prevention of Asthmatic Death

Allergology International, 2005
Physicians are very much concerned that death from asthma has not significantly declined despite modern treatment. Since most asthma deaths take place at home it is mandatory to keep in mind that adequate management should be commenced as early as ...
Seishiro Miyagi, Tsuyoshi Matsumoto, Tomoo Kisyaba, Hitoshi Tamaki   +3 more
doaj   +1 more source