Results 71 to 80 of about 1,807,776 (311)

Idiopathic pulmonary arterial hypertension and co-existing lung disease: is this a new phenotype?

Pulmonary Circulation, 2020
Patients classified as idiopathic pulmonary arterial hypertension (defined as Group 1 on European Respiratory Society (ERS)/European Cardiac Society (ESC) criteria) may have evidence of minor co-existing lung disease on thoracic computed tomography.
Andrew J. Peacock, Yi Ling, Martin K. Johnson, David G. Kiely, Robin Condliffe, Charlie A. Elliot, J. Simon R. Gibbs, Luke S. Howard, Joanna Pepke-Zaba, Karen K.K. Sheares, Paul A. Corris, Andrew J. Fisher, James L. Lordan, Sean Gaine, J. Gerry Coghlan, S. John Wort, Michael A. Gatzoulis   +16 more
doaj   +1 more source

Physical activity counselling during pulmonary rehabilitation in patients with COPD : a randomised controlled trial [PDF]

, 2015
Background Pulmonary rehabilitation programs only modestly enhance daily physical activity levels in patients with chronic obstructive pulmonary disease (COPD). This randomised controlled trial investigates the additional effect of an individual activity
Burtin, Chris, Decramer, Marc, Demeyer, Heleen, Dobbels, Fabienne, Gosselink, Rik, Janssens, Wim, Langer, Daniel, Troosters, Thierry, van Remoortel, Hans   +8 more
core   +3 more sources

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Impact of patient positioning on hemodynamic assessment: A comparison of supine and upright right heart catheterization

Physiological Reports
The impact of patient positioning on PCWP measurement and PH classification is underexplored. This study evaluates the differences in hemodynamic assessments between supine and upright RHC.
Mohammed A. Chowdhury, Johanna Squires, David M. Systrom, Aaron B. Waxman   +3 more
doaj   +1 more source

Assessment of pulmonary edema: principles and practice [PDF]

, 2018
Pulmonary edema increasingly is recognized as a perioperative complication affecting outcome. Several risk factors have been identified, including those of cardiogenic origin, such as heart failure or excessive fluid administration, and those related to ...
Assaad, Sherif, Friedman, Malcolm B., Kratzert, Wolf B., Perrino, Albert, Shelley, Benjamin   +4 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Isolated interrupted inferior vena cava with azygos continuation mimicking paraesophageal lymph node enlargement

Monaldi Archives for Chest Disease, 2016
We report a case of interrupted inferior vena cava with azygos continuation diagnosed as a isolated finding in a patient with lung carcinoma. Findings of the unopacified CT scan initially simulated a paraesophageal lymphadenopathy.
U. Yılmaz, H. Halilcolar, I. Unsal, S. Yapıcıoglu, Y. Yıldırım, M. Apaydın   +5 more
doaj   +1 more source

Storage conditions of high‐fat diets affect pulmonary inflammation

Physiological Reports, 2021
Obesity alters the risks and outcomes of inflammatory lung diseases. It is important to accurately recapitulate the obese state in animal models to understand these effects on the pathogenesis of disease.
Marta Kokoszynska, Niki D. Ubags, Joseph J. Bivona III, Sebastian Ventrone, Leah F. Reed, Anne E. Dixon, Matthew J. Wargo, Matthew E. Poynter, Benjamin T. Suratt   +8 more
doaj   +1 more source

Pulmonary rehabilitation : insight into current trends [PDF]

, 2010
Pulmonary rehabilitation is a widely accepted therapeutic tool used to improve the quality of life and functional capacity of individuals with chronic lung disease.
Montefort, Stephen, Sciriha, Anabel
core