Results 81 to 90 of about 11,770,891 (406)

Validation of the Clinical COPD questionnaire in Italian language [PDF]

open access: yes, 2005
BACKGROUND: The development and validation study of the Clinical Chronic Obstructive Disease (COPD) Questionnaire (CCQ) has recently been published in this journal. The CCQ is the first questionnaire that incorporates both clinician and patient guideline
Bonatti, Chiara   +6 more
core   +2 more sources

The GOLD Summit on chronic obstructive pulmonary disease in low- and middle-income countries.

open access: yesThe International Journal of Tuberculosis and Lung Disease, 2019
Chronic obstructive pulmonary disease (COPD) is one of the top three causes of death worldwide, but governments and non-governmental organisations have not given its prevention and treatment the priority it requires. This is particularly true in low- and
D. Halpin   +13 more
semanticscholar   +1 more source

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

open access: yesFEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu   +8 more
wiley   +1 more source

Impact of patient positioning on hemodynamic assessment: A comparison of supine and upright right heart catheterization

open access: yesPhysiological Reports
The impact of patient positioning on PCWP measurement and PH classification is underexplored. This study evaluates the differences in hemodynamic assessments between supine and upright RHC.
Mohammed A. Chowdhury   +3 more
doaj   +1 more source

The molecular genetics and cellular mechanisms underlying pulmonary arterial hypertension [PDF]

open access: yes, 2012
Pulmonary arterial hypertension (PAH) is an incurable disorder clinically characterised by a sustained elevation of mean arterial pressure in the absence of systemic involvement.
Machado, Rajiv
core   +2 more sources

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

Amiodarone-Induced Pulmonary Toxicity - A Frequently Missed Complication. [PDF]

open access: yes, 2016
IntroductionAmiodarone is often used in the suppression of tachyarrhythmias. One of the more serious adverse effects includes amiodarone pulmonary toxicity (APT).
Dang, Natasha   +4 more
core   +2 more sources

Pulmonary hydatid disease [PDF]

open access: yesThorax, 1972
Radiographic evidence is presented in confirmation of the contention that uncomplicated isolated pulmonary hydatid cysts are seldom completely circular and can be confidently recognized as hydatid cysts radiographically and fluoroscopically.
openaire   +2 more sources

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

Analysis of prevalence and prognosis of type 2 diabetes mellitus in patients with acute exacerbation of COPD

open access: yesBMC Pulmonary Medicine, 2021
Background For patients with acute exacerbation of COPD (AECOPD), type 2 diabetes mellitus (T2DM) as comorbidity have poor outcomes. However, data on the impact of previously diagnosed and new- diagnosed T2DM in such a patient population is lacking ...
Li Lin   +3 more
doaj   +1 more source

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