Results 101 to 110 of about 37,991 (280)

Clinical Trial: A Phase 2b Study to Evaluate the Efficacy and Safety of MK‐3655 in Individuals With Pre‐Cirrhotic MASH

open access: yesAlimentary Pharmacology &Therapeutics, Volume 61, Issue 7, Page 1152-1162, April 2025.
This Phase 2b study examined the safety and efficacy of MK‐3655, a monoclonal antibody that binds β‐klotho and selectively activates the FGFR1c/β‐klotho co‐receptor complex, in patients with pre‐cirrhotic MASH. Treatment with MK‐3655 was generally well tolerated and resulted in a modest reduction in liver fat content at 24 weeks.
Annaswamy Raji   +11 more
wiley   +1 more source

Automatic lobe segmentation using attentive cross entropy and end-to-end fissure generation [PDF]

open access: yesarXiv, 2023
The automatic lung lobe segmentation algorithm is of great significance for the diagnosis and treatment of lung diseases, however, which has great challenges due to the incompleteness of pulmonary fissures in lung CT images and the large variability of pathological features.
arxiv  

Dupilumab Efficacy and Safety in Patients With Persistent Asthma: Asia–Pacific Region

open access: yesClinical &Experimental Allergy, EarlyView.
Asthma prevalence is increasing in the Asia–Pacific region, and this population is frequently underrepresented in phase 3 clinical studies. We demonstrate Dupilumab's efficacy and safety among patients with uncontrolled moderate‐to‐severe type 2 asthma.
Qingling Zhang   +13 more
wiley   +1 more source

Interleukin-18 [PDF]

open access: yes, 2003
Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses.
Gracie, J.A.   +2 more
core   +1 more source

Loeffler's syndrome in a child: A rare radiological and histopathological diagnosis

open access: yesRadiology Case Reports, 2022
Loffler syndrome is an uncommon, self-limited, benign pulmonary eosinophilia that usually lasts less than a month. Abnormal chest radiography occurs in 95% of patients; however, computed tomography findings are not well described.
Kiem Hao Tran, A/Prof, PhD   +3 more
doaj  

Eosinophilic pneumonias. A clinical case of acute eosinophilic pneumonia associated with sertraline and literature review

open access: yesItalian Journal of Medicine, 2013
Background: Acute eosinophilic pneumonia (AEP) is one of the heterogeneous group of disorders termed eosinophilic lung diseases showing an abnormal accumulation of eosinophils in distal airways, air spaces, and the interstitial compartment of the lung ...
Roberto Serini   +5 more
doaj   +1 more source

Characterizing Pulmonary Fibrosis Patterns in Post-COVID-19 Patients through Machine Learning Algorithms [PDF]

open access: yesarXiv, 2023
The COVID-19 pandemic has left a lasting impact on global healthcare systems, with increasing evidence of pulmonary fibrosis emerging as a post-infection complication. This study presents a comprehensive analysis of pulmonary fibrosis patterns in post-COVID-19 patients from South and Central Iraq, employing advanced machine learning algorithms.
arxiv  

Complementary Analysis of Local and Systemic Effects of Dupilumab in Paediatric AD Using Tape Strips and Serum

open access: yesClinical &Experimental Allergy, EarlyView.
ABSTRACT Objective This study investigates local and systemic immune‐related proteins in tape strips and serum of paediatric atopic dermatitis (AD) patients treated with dupilumab, and explores their correlation with clinical severity. Methods Twenty paediatric AD patients (< 18 years) starting dupilumab treatment were included.
Lisa P. van der Rijst   +6 more
wiley   +1 more source

Validation of a food frequency questionnaire for children and adolescents aged 4 to 11 years living in Salvador, Bahia.

open access: yes, 2012
OBJECTIVE: To assess the validity of a food frequency questionnaire (FFQ) by applying it to children and adolescents living in Salvador, Bahia. METHODS: The validity of this FFQ with 98 food items was investigated among 108 children and adolescents who ...
Assis, AMO   +8 more
core   +2 more sources

Granulomatous fasciitis followed by morphea profunda: Is granulomatous fasciitis part of a spectrum of deep morphea? A case report and review of the literature. [PDF]

open access: yes, 2018
Although eosinophilic fasciitis is known to be part of the deep morphea spectrum, this first report of the coexistence of granulomatous fasciitis and morphea profunda suggests that granulomatous fasciitis may also be a part of the spectrum of deep ...
Christensen, Angie   +5 more
core   +1 more source

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