Results 221 to 230 of about 1,859,821 (399)

Immunobiology of pulmonary fibrosis. [PDF]

Front Immunol
Bindu S, Yasmin H, Barman U, Pandit S, Masmoudi K, Kishore U.   +5 more
europepmc   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Pulmonary fibrosis and COVID-19: the potential role for antifibrotic therapy

The Lancet Respiratory Medicine, 2020
Peter M. George, A. Wells, R. G. Jenkins
semanticscholar   +1 more source

Macrophage–Derived Ferritin Exacerbates Silica‐Induced Pulmonary Fibrosis via PIK3R2‐Mediated Fibroblast Differentiation

Advanced Science, EarlyView.
This study identifies ferritin as a pivotal mediator of silica‐induced pulmonary fibrosis. Macrophage‐derived ferritin drives fibroblast‐to‐myofibroblast differentiation via the PIK3R2/SMAD pathway, while ferritin knockdown alleviates fibrosis. These findings define ferritin as both a biomarker and pathogenic driver, highlighting ferritin‐PIK3R2 ...
Liqun Wang, Xuxi Chen, Hongying Quan, Rui Qian, Shuyu Gong, Qiurong He, Ying Gao, Ajia Axi, Manyu Zhao, Qin Zhang, Ling Zhang, Lijun Peng, Xin Sun, Ben Zhang, Yuqin Yao   +14 more
wiley   +1 more source

The Mechanism of Oxidative Stress in Pulmonary Fibrosis and Research Progress. [PDF]

Antioxidants (Basel)
Xu D, Wang Q, Lyu M, Huang C, Yuan X, Chen X, Huang Y.   +6 more
europepmc   +1 more source

INTERSTITIAL PULMONARY FIBROSIS

The Journal of Thoracic and Cardiovascular Surgery, 1964
W B, FORD, J W, GIACOBINE, H R, MADOFF, M, SACHS   +3 more
openaire   +2 more sources

Artificial Intelligence‐Driven Soft Bioelectronics for Self‐Powered Respiration Monitoring

Advanced Science, EarlyView.
Artificial intelligence‐driven soft bioelectronics for self powered respiration monitoring based on triboelectric nanogenerators (TENGs), piezoelectric nanogenerators (PENGs), and magnetoelastic generators (MEGs) enable continuous and multi‐scenario respiratory biomechanical data collection. Coupled with machine learning and big data driven diagnostics,
Xinkai Xu, Xiao Xiao, Rui Guo, Jun Chen
wiley   +1 more source

Is the combination of Myelodysplastic syndromes and pulmonary fibrosis accidental or inevitable? [PDF]

Multidiscip Respir Med
He Y, Li Y, Wang Y, Zhang J, Chen H, Chen J, Zhao Y.   +6 more
europepmc   +1 more source

Pyruvate kinase M2 modulates mitochondrial dynamics and EMT in alveolar epithelial cells during sepsis-associated pulmonary fibrosis

Jinhua Feng, Xi Huang, Yawen Peng, Wenyu Yang, Xinyi Yang, Ri Tang, Qiaoyi Xu, Yuan Gao, Zhengyu He, Shunpeng Xing, Shuya Mei   +10 more
openalex   +1 more source

Direct Extracellular Matrix Modulation Attenuates Intestinal Fibrosis via a Fibronectin‐Targeted Approach

Advanced Science, EarlyView.
Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma, Siyu Yang, Tengkai Wang, Di Zhang, Hewei Wu, Shichen Fu, Xiaohan Wan, Lixiang Li, Xiuli Zuo, Yanqing Li, Jiaoyang Lu   +10 more
wiley   +1 more source