Results 71 to 80 of about 121,342 (296)

Characterizing Pulmonary Gas Exchange in Inborn Errors of Immunity Using Hyperpolarized Xenon MRI

Journal of Human Immunity
RationaleInborn errors of immunity (IEIs) predispose individuals to recurrent respiratory infections and immune dysregulation, which together can drive inflammatory lung complications, including interstitial lung disease and thickening of the ...
Ernest Hoptioncann, Rachel Eddy, Catherine Biggs, Jonathan Rayment   +3 more
doaj   +1 more source

A perpetual switching system in pulmonary capillaries [PDF]

, 2019
Of the 300 billion capillaries in the human lung, a small fraction meet normal oxygen requirements at rest, with the remainder forming a large reserve.
Bohlen, H. Glenn, Crockett, Edward S., Doerschuk, Claire M., Glenny, Robb W., Jaryszak, Eric M., King, Judy A. C., Peterson, Amanda J., Presson, Robert G., Jr., Tanner, Judith A., Wagner, Wiltz W., Jr.   +9 more
core   +1 more source

On Top of the Alveolar Epithelium: Surfactant and the Glycocalyx [PDF]

, 2020
Gas exchange in the lung takes place via the air-blood barrier in the septal walls of alveoli. The tissue elements that oxygen molecules have to cross are the alveolar epithelium, the interstitium and the capillary endothelium.
Hegermann, Jan, Kuebler, Wolfgang M., Lopez-Rodriguez, Elena, Matuszak, Jasmin, Nouailles, Geraldine, Ochs, Matthias, Simmons, Szandor, Timm, Sara, Witzenrath, Martin   +8 more
core   +1 more source

Bifunctional Artificial Enzymes‐Loaded Microgels With LOX‐ and CAT‐Like Activities for Metabolic Reprogramming and Scarless Wound Repair

Advanced Science, EarlyView.
A bifunctional lactate oxidase‐like and catalase‐like artificial enzyme (Metazyme) is integrated into a rod‐shaped microgel (MetaRgel) to enable cascade lactate oxidation and oxygen regeneration. By reprogramming the wound metabolic microenvironment, MetaRgel alleviates excessive lactate accumulation, oxidative stress, hypoxia, and inflammation ...
Yongyuan Kang, Pai Peng, Liang Song, Qiaoxuan Wang, Zilong Zhong, Dongchao Qiu, Yunfan Liu, Kefei Zhao, Xiaofei Dong, Changyou Gao   +9 more
wiley   +1 more source

Management of two circulations in a COVID‐19 patient with secondary superinfection

Physiological Reports, 2023
Optimal oxygenation in the intensive care unit requires adequate pulmonary gas exchange, oxygen‐carrying capacity in the form of hemoglobin, sufficient delivery of oxygenated hemoglobin to the tissue, and an appropriate tissue oxygen demand. In this Case
Rachael Stadlen, Arun K. Singhal, Robert M. Reed, Jeffrey D. Hasday, Melissa L. Bates, Gregory A. Schmidt, Michael Eberlein   +6 more
doaj   +1 more source

Synchronization‐Dissipation in the Cardiorespiratory System

Advanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border, Alain Nogaret, Andrew Lefevre, Vishal Jain   +3 more
wiley   +1 more source

Angiotensin II type 2 receptor agonist Compound 21 attenuates pulmonary inflammation in a model of acute lung injury

Journal of Inflammation Research, 2018
Mario Menk, Jan Adriaan Graw, Clarissa von Haefen, Hendrik Steinkraus, Burkhard Lachmann, Claudia D Spies, David Schwaiberger Department of Anesthesiology and Operative Intensive Care Medicine, Charité – University Medicine Berlin ...
Menk M, Graw JA, von Haefen C, Steinkraus H, Lachmann B, Spies CD, Schwaiberger D   +6 more
doaj  

Understanding alveolarization to induce lung regeneration

Respiratory Research, 2018
Background Gas exchange represents the key physiological function of the lung, and is dependent upon proper formation of the delicate alveolar structure. Malformation or destruction of the alveolar gas-exchange regions are key histopathological hallmarks
José Alberto Rodríguez-Castillo, David Bravo Pérez, Aglaia Ntokou, Werner Seeger, Rory E. Morty, Katrin Ahlbrecht   +5 more
doaj   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

The Usefulness of Submaximal Exercise Gas Exchange in Pulmonary Arterial Hypertension: A Case Series

Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2010
Introduction Submaximal exercise gas exchange may be a useful tool to track responses to therapy in pulmonary arterial hypertension (PAH) patients. Methods Three patients diagnosed with idiopathic PAH, on differing therapies, were included.
Paul R. Woods, Robert P. Frantz, Bruce D. Johnson   +2 more
doaj   +1 more source