Results 61 to 70 of about 58,255 (295)

Heterojunction‐Engineered Mass Spectrometry Platform for Deciphering Serum Metabolic Fingerprints in Diagnosis of Respiratory Diseases

Advanced Science, EarlyView.
Hollow Co3O4/TiO2 heterojunctions are engineered for high‐throughput laser desorption/ionization mass spectrometry. The built‐in electric field drives efficient charge separation and photothermal conversion, while the hierarchical mesoporous network enables robust salt and protein tolerance.
Junyu Chen, Chaoqi Wang, Xi Yu, Yuming Jiang, Yijiao Qu, Huihui Fu, Yuyin Bu, Xiaoyong Zhang, Zongxiu Nie   +8 more
wiley   +1 more source

Simulation and Analysis of an Integrated Cardiopulmonary Gas Exchange Model Under Different Pathological Conditions

IEEE Access
The development of individualised diagnosis and treatment plans depends on accurate modelling of cardiopulmonary dynamics. A comprehensive cardiopulmonary model that incorporates gas exchange, lung mechanics and cardiovascular interactions has been ...
K. Anjana, Shantanu Saha, N. Selvaganesan   +2 more
doaj   +1 more source

Management of two circulations in a COVID‐19 patient with secondary superinfection

Physiological Reports, 2023
Optimal oxygenation in the intensive care unit requires adequate pulmonary gas exchange, oxygen‐carrying capacity in the form of hemoglobin, sufficient delivery of oxygenated hemoglobin to the tissue, and an appropriate tissue oxygen demand. In this Case
Rachael Stadlen, Arun K. Singhal, Robert M. Reed, Jeffrey D. Hasday, Melissa L. Bates, Gregory A. Schmidt, Michael Eberlein   +6 more
doaj   +1 more source

Pulmonary ventilation and gas exchange in bronchiectasis [PDF]

Thorax, 1971
The subdivisions of the lung volume, pulmonary mechanics, and resting steady state pulmonary transfer factor were measured in 31 patients with bronchographically proven bronchiectasis. In seven patients the process of gas exchange was further investigated by fractionating the total alveolar-arterial oxygen tension gradient into diffusion, distribution,
J N, Pande, B P, Jain, R G, Gupta, J S, Guleria   +3 more
openaire   +2 more sources

Exercise response and the effect of supplemental oxygen during interval training on O2 uptake kinetics, blood lactate levels, and endurance performance in patients with mild, moderate and severe cystic fibrosis [PDF]

, 2011
Background: Exercise performance is reduced in individuals with moderate to severe cystic fibrosis (CF). A ventilatory mechanical limitation, arterial hypoxemia, cardiovascular abnormalities, alteration in O2 uptake kinetics and reduced muscle ...
Reuveny, Ronen
core  

Inhaled nitric oxide reverses hypoxic pulmonary vasoconstriction without impairing gas exchange

, 1993
Nitric oxide (NO) is an endogenous endothelium-derived relaxing factor that participates in the regulation of vascular tone. We studied the effects of inhaled NO gas on transient hypoxic pulmonary vasoconstriction and normal lungs in mechanically ...
U. Pison, F. A. Lopez, K. J. Falke, R. Rossaint, C. F. Heidelmeyer   +4 more
core   +1 more source

SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells

Animal Models and Experimental Medicine, EarlyView.
The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang, Xuepei Lei, Yiying Huang, Jiaming Tang, Guiying Shi, Hang Li, Lin Bai   +6 more
wiley   +1 more source

Characterizing Pulmonary Gas Exchange in Inborn Errors of Immunity Using Hyperpolarized Xenon MRI

Journal of Human Immunity
RationaleInborn errors of immunity (IEIs) predispose individuals to recurrent respiratory infections and immune dysregulation, which together can drive inflammatory lung complications, including interstitial lung disease and thickening of the ...
Ernest Hoptioncann, Rachel Eddy, Catherine Biggs, Jonathan Rayment   +3 more
doaj   +1 more source

Regional gas exchange evaluation during ex vivo lung perfusion in a swine model of localized lung dysfunction

Animal Models and Experimental Medicine, EarlyView.
Abstract Background Ex vivo lung perfusion (EVLP) allows the evaluation of lungs that do not meet standard transplantation criteria. Current procedures do not permit the identification of regional functional deficits. We investigated the feasibility of assessing lobar gas exchange during EVLP in a swine model.
Giulia Maria Ruggeri, Elena Chiodaroli, Matteo Montoli, Sara Pieropan, Alessandro Santini, Gianluca Lopez, Michele Battistin, Luigi Vivona, Sebastiano Maria Colombo, Jacopo Fumagalli, Eleonora Carlesso, Stefano Ferrero, Lorenzo Rosso, Stefano Gatti, Antonio Maria Pesenti, Giacomo Grasselli, Alberto Zanella   +16 more
wiley   +1 more source

Understanding alveolarization to induce lung regeneration

Respiratory Research, 2018
Background Gas exchange represents the key physiological function of the lung, and is dependent upon proper formation of the delicate alveolar structure. Malformation or destruction of the alveolar gas-exchange regions are key histopathological hallmarks
José Alberto Rodríguez-Castillo, David Bravo Pérez, Aglaia Ntokou, Werner Seeger, Rory E. Morty, Katrin Ahlbrecht   +5 more
doaj   +1 more source