Results 51 to 60 of about 121,342 (296)
Advanced Healthcare Materials, EarlyView.This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu +10 more
wiley +1 more source
BMC Pulmonary MedicineBackground Pulmonary air embolism (AE) and thromboembolism lead to severe ventilation-perfusion defects. The spatial distribution of pulmonary perfusion dysfunctions differs substantially in the two pulmonary embolism pathologies, and the effects on ...
József Tolnai +7 more
doaj +1 more source
Clinical and Translational Medicine, 2020 Patients with severe COVID‐19 disease have been characterized as having the acute respiratory distress syndrome (ARDS). Critically ill COVID‐19 patients have relatively well‐preserved lung mechanics despite severe gas exchange abnormalities, a feature ...
Hooman D. Poor +9 more
doaj +1 more source
Hyperpolarized Xe MR imaging of alveolar gas uptake in humans. [PDF]
PLoS ONE, 2010 One of the central physiological functions of the lungs is to transfer inhaled gases from the alveoli to pulmonary capillary blood. However, current measures of alveolar gas uptake provide only global information and thus lack the sensitivity and ...
Zackary I Cleveland +10 more
doaj +1 more source
Children, 2021 The diagnosis of congenital diaphragmatic hernia (CDH) is associated with significant morbidity and mortality. Survival of neonates with CDH has improved recently, although the clinical course is complicated by sequelae of hypoplastic pulmonary ...
Deepika Sankaran +4 more
doaj +1 more source
Off-pump coronary bypass surgery adversely affects alveolar gas exchange [PDF]
, 2008 While the introduction of off-pump myocardial revascularization (OPCAB) has initially shown promise in reducing respiratory complications inherent to conventional coronary surgery, it has failed to eradicate them.
Biočina, Bojan +7 more
core +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Pulmonary Medicine, 2012 Patients with pulmonary arterial hypertension (PAH) and heart failure (HF) display many abnormalities in respiratory gas exchange. These abnormalities are accentuated with exercise and track with disease severity.
Chul-Ho Kim +3 more
doaj +1 more source
Pulmonary gas exchange in elderly subjects [PDF]
European Respiratory Journal, 1996 Although important alterations in structure and function develop with age, the hypothesis that the lungs are capable of maintaining adequate gas exchange for the maximum human life span is generally accepted. This hypothesis was examined by measuring arterial oxygen and carbon dioxide tension (Pa,O2 and Pa,CO2) alveolo-arterial differences in oxygen ...
H, Guénard, R, Marthan
openaire +2 more sources
Advanced Materials, EarlyView.A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade +19 more
wiley +1 more source