Comorbidities of patients in tiotropium clinical trials : comparison with observational studies of patients with chronic obstructive pulmonary disease [PDF]
, 2015 Acknowledgments The authors are fully responsible for all content and editorial decisions made, were involved at all stages of manuscript development, and have approved the final version for publication.
Celli, Bartolome +5 more
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Advanced Functional Materials, EarlyView.Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source
Lung Function in Young Adults and Risk of Cardiovascular Events Over 29 Years: The CARDIA Study
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 Background Diminished peak lung function in young adulthood is a risk factor for future chronic obstructive pulmonary disease. The association between lung disease and cardiovascular disease later in life is well documented.
Michael J. Cuttica +12 more
doaj +1 more source
The molecular genetics and cellular mechanisms underlying pulmonary arterial hypertension [PDF]
, 2012 Pulmonary arterial hypertension (PAH) is an incurable disorder clinically characterised by a sustained elevation of mean arterial pressure in the absence of systemic involvement.
Machado, Rajiv
core +2 more sources
Cell Calcification Models and Their Implications for Medicine and Biomaterial Research
Advanced Healthcare Materials, EarlyView.Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter +5 more
wiley +1 more source
Chronic obstructive pulmonary disease and chronic heart failure in elderly people: literature review
Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2016 The article provides literature review on the subject: chronic obstructive pulmonary disease: pathogenesis, principles of treatment, the course of heart failure in elderly people with comorbide pathology (chronic obstructive pulmonary disease and cardio ...
V. A. Gubkina +5 more
doaj +1 more source
Sex-dependent influence of endogenous estrogen in pulmonary hypertension [PDF]
, 2014 Rationale: The incidence of pulmonary arterial hypertension (PAH) is greater in women suggesting estrogens may play a role in the disease pathogenesis. Experimentally, in males exogenously administered estrogen can protect against PH; however in models ...
Audrey F. Wright +17 more
core +1 more source
A Computational Journey Toward an Optimal Design for Metamaterial Epicardial Passive Sleeves
Advanced Healthcare Materials, EarlyView.Passive epicardial sleeves are evaluated in 3D in‐silico heart models to reveal how sleeve geometry, stiffness, anisotropy, and metamaterial architecture influence cardiac mechanics after myocardial infarction. A continuum‐to‐auxetic design exploration shows that region‐specific mechanical engagement can reduce infarct bulging and modulate torsional ...
Vahid Naeini +8 more
wiley +1 more source
The trajectory to diagnosis with pulmonary arterial hypertension: a qualitative study [PDF]
, 2012 Objectives To investigate the patient's experience of the trajectory to receiving a diagnosis of pulmonary arterial hypertension (PAH) and inform the provision of care for this patient group.
Armstrong, I +4 more
core +2 more sources
Passive leg raising: can it help in the diagnosis of pulmonary hypertension due to left heart disease [PDF]
, 2021 А. В. Волков +3 more
openalex +1 more source