Results 101 to 110 of about 8,356,254 (304)

Karma of Cardiovascular Disease Risk Factors for Prevention and Management of Major Cardiovascular Events in the Context of Acute Exacerbations of Chronic Obstructive Pulmonary Disease

Frontiers in Cardiovascular Medicine, 2019
There is compelling epidemiological evidence that airway exposure to cigarette smoke, air pollution particles, as well as bacterial and viral pathogens is strongly related to acute ischemic events.
Liliana Crisan, Nathan Wong, Don D. Sin, Hwa Mu Lee, Hwa Mu Lee   +4 more
doaj   +1 more source

Real‐World Safety of Concomitant Colchicine and Statin Therapy

Arthritis Care &Research, EarlyView.
Objective This study aimed to evaluate the risk of clinically meaningful muscle‐ and liver‐related outcomes associated with concomitant colchicine–statin therapy in a real‐world setting, and to determine whether concomitant therapy increases the incidence of toxicity compared with either agent alone.
Roni Meidan, Ranel Loutati, Dan Caspi, Ori Elkayam, Ran Abuhasira, Tali Eviatar   +5 more
wiley   +1 more source

Angiogenesis in Chronic Obstructive Pulmonary Disease [PDF]

, 2012
Angiogenesis is a crucial component of lung pathophysiology, not only in cancer but also in other disorders, such as chronic obstructive pulmonary disease (COPD).
Gaetano Santulli, Alessandro Matarese
core  

Quantification of dyspnoea using descriptors: development and initial testing of the Dyspnoea-12 [PDF]

, 2010
Rationale: Dyspnoea is a debilitating and distressing symptom that is reflected in different verbal descriptors. Evidence suggests that dyspnoea, like pain perception, consists of sensory quality and affective components.
Shuldham, C, Yorke, J., Shuldham, C., Yorke, J, Jones, PW, Jones, P. W., Moosavi, SH, Moosavi, S. H.   +7 more
core   +1 more source

Development of Patient‐Reported Outcome Measures for Early Systemic Sclerosis Across Disease Subtypes

Arthritis Care &Research, Accepted Article.
Objective Existing patient‐reported outcome (PRO) measures for systemic sclerosis (SSc) have important limitations, including inadequate coverage of early disease and limited inclusion of diffuse cutaneous (dcSSc) and limited cutaneous (lcSSc) subtypes.
George J. Greene, Chelsea Rose Perschon, Emilie Jaeger, Alain Lescoat, David Cella, Dinesh Khanna   +5 more
wiley   +1 more source

Non‐Additive Criteria Assessment in Sustainability Evaluation of High Entropy Alloys: A Toxicity‐Weighted Framework

Advanced Engineering Materials, EarlyView.
Sustainability assessment requires methodologies that appropriately distinguish between additive and non‐additive material properties. A toxicity‐weighted scoring system is developed and applied that accounts for the disproportionate influence of highly toxic constituents through nonlinear weighting functions, providing more realistic estimates than ...
Seth Mehalic, Oladele A. Ogunseitan, Julie M. Schoenung   +2 more
wiley   +1 more source

Clinical and fiberoptic endoscopic assessment of swallowing in patients with chronic obstructive pulmonary disease

International Archives of Otorhinolaryngology, 2013
Summary Introduction: Chronic obstructive pulmonary disease is characterized by progressive and partially reversible obstruction of pulmonary airflow.
Marina Rodrigues Bueno Macri, Jair Mendes Marques, Rosane Sampaio Santos, Ana Maria Furkim, Irinei Melek, Daniel Rispoli, Maria Cristina de Alencar Nunes   +6 more
doaj   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Psychological distress and chronic obstructive pulmonary disease in the Renfrew and Paisley (MIDSPAN) study [PDF]

, 2006
Background: This study examined whether psychological distress might be a predictor of chronic obstructive pulmonary disease (COPD). Method: The relation between psychological distress at baseline, measured by the general health questionnaire (GHQ ...
Rasul, F., Hart, Carole L., Stansfeld, SA, Pembroke, T.P.I., Hart, CL, Pembroke, TPI, Hart, C., Rasul, F, Smith, George Davey, Stansfeld, S.A., Pembroke, Thomas P I, Davey Smith, G., Davey Smith, G, Stansfeld, Stephen A., Rasul, Farhat   +14 more
core   +1 more source

Topically Delivered Treg‐Attracting Microparticle‐Hydrogel Composites Recruit Regulatory T Cells and Limit Cardiac Injury After Severe Ischemia

Advanced Healthcare Materials, EarlyView.
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli, Alexis T. Reese, Jordan J. P. Warunek, Betsy Ann Varghese, Canxing Lin, Jeffery J. Baust, Brenda McMahon, Steven R. Little, Hēth R. Turnquist   +8 more
wiley   +1 more source