Results 121 to 130 of about 8,356,254 (304)

Pulmonary hypertension associated with left heart disease and lung disease, high-altitude disease, and chronic thromboembolic pulmonary hypertension

open access: yes, 2016
Conditions discussed are hypertension associated with left heart disease and lung disease, and chronic thromboembolic pulmonary hypertension.
Bernard J. Gersh   +2 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

METHOD FOR THE PREDICTION OF THE DEVELOPMENT OF CHRONIC PULMONARY HEART IN COAL WORKERS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

open access: yesActa Biomedica Scientifica, 2013
452 miners at the age of40-55years (average age is 50,9 ± 0,2 years) with chronic obstructive pulmonary disease were studied. Chronic pulmonary heart was detected in 289 patients (63,9 %).
O. Yu. Korotenko   +2 more
doaj  

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

open access: yesAdvanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni   +17 more
wiley   +1 more source

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

open access: yesAdvanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch   +6 more
wiley   +1 more source

Primitive hepatic venous plexus in a child with scimitar syndrome and pulmonary sequestration [PDF]

open access: yes, 2013
This article reports a case of scimitar syndrome with pulmonary sequestration, persistent primitive hepatic venous plexus and stenosis of the inferior vena cava in a child presenting with failure to thrive.
Paterson, Annie   +2 more
core  

Adult Congenital Heart Disease

open access: yesJACC: Case Reports, 2021
Margarita Brida, MD, PhD   +1 more
doaj   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

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