Results 211 to 220 of about 6,741,320 (294)

Transition From Pulmonary to Gastrointestinal Hemorrhage: A Rare Case of Hematemesis in an Adolescent With Chronic Pulmonary Hypertension and Valvular Regurgitation. [PDF]

Clin Case Rep
Ashraf B, Hussain MU, Zahid A, Sohail F, Shoukat SEA, Yattassaye M, Ashraf N.   +6 more
europepmc   +1 more source

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

Advanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu, Ruotong Li, Xiaoyue Zhang, Dandan Chen, Jianmeng Yang, Mengmeng Li, Yuhan Yin, Ya Wang, Yuqiu Tian, Haoling Yan, Dan Cui, Jiangping Song, Gaoliang Ouyang   +12 more
wiley   +1 more source

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

Advanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou, Lei Zhang, Xingyu Cai, Jiajia Su, Guangyu Dai, Xue Chen, Hanming Wang, Jia Hua, Jianping Liu, Chunmeng Sun, Xiancheng Chen, Erhao Wang, Wenli Zhang   +12 more
wiley   +1 more source

Right Ventricular Isovolumetric Relaxation Time is Associated with Pulmonary Vascular Load and Functional Limitation in Chronic Obstructive Pulmonary Disease. [PDF]

Int J Chron Obstruct Pulmon Dis
Dong F, Tanaka Y, Okamura K, Higa K, Kaburaki S, Sato Y, Tanaka T, Shimizu A, Takeuchi S, Kubota Y, Taniuchi N, Kamio K, Kasahara K, Wu L, Seike M, Hino M, Kimura H.   +16 more
europepmc   +1 more source

Expert Consensus on Influenza Vaccine and Pneumococcal Vaccination in Elderly People With Chronic Respiratory Diseases (2024)

AGING MEDICINE, EarlyView.
This consensus describes the protective effect and safety of influenza and pneumococcal vaccines, and vaccination recommendations, aiming to promote the vaccination rate, better play the role of vaccines in preventing influenza and pneumococcal diseases, and reduce the occurrence of respiratory infections and related serious complications in elderly ...
Lijing Wang, Qiao Yu, Qiong Chen, Pulin Yu, Expert Committee of Consensus Opinion on Influenza Vaccine and Pneumococcal Vaccine Vaccination for Elderly People with Chronic Respiratory Diseases, Respiratory Group of Chinese Geriatrics Society, Yunhua Bai, Yufeng Du, Luzhao Feng, Lidong Gao, Lingyun Gao, Baimei He, Junguang Jiang, Wenjing Jiang, Yayun Nan, Zhibin Peng, Yun Peng, Zhujun Shao, Jin Tan, Yingxuan Tian, Bingxiang Wang, Yuhong Wang, Wei Wu, Jianqin Wu, Xiuping Wu, Meizhe Xin, Wei Xiong, Guogang Zhang, Qiang Zhang, Xiangyu Zhang, Zhimian Zhang, Xiongwen Zhou   +31 more
wiley   +1 more source

No time for delay: a complicated case of infective endocarditis in a young patient with congenital heart disease. [PDF]

Br J Cardiol
Lankaputhra M, Caldaroni F, Lee MG.
europepmc   +1 more source

Evaluation and Ranking for Scientific, Transparent and Applicable of Chinese Geriatrics Guidelines and Consensus Published in 2023

AGING MEDICINE, EarlyView.
Evaluation of geriatric guidelines and consensus in 2023 using the STAR tool shows improved scientificity and transparency compared to 2022, though protocol development, funding, and clinical issues need refinement. Collaborative efforts among developers, journals, and experts are key to further elevating quality. ABSTRACT Objectives This study aims to
Daiping Li, Chao Gao, Xiaoli Huang, Ling Kang, Birong Dong, Jirong Yue, the Specialized Committee for Geriatric Medicine of the STAR, Daiping Li, Chao Gao, Xiaoli Huang, Ling Kang, Birong Dong, Jirong Yue   +12 more
wiley   +1 more source

Interpreting prognostic asymmetry in heart failure-chronic obstructive pulmonary disease overlap. [PDF]

ESC Heart Fail
Cheng H, Zhang Z, Lu F.
europepmc   +1 more source

Impact of Acute Functional Decline on Frailty and Mortality in Acutely Hospitalized Older Persons

AGING MEDICINE, EarlyView.
Older persons with acute functional decline are often severely frail. Male sex, cognitive impairment, diabetes mellitus type 2, cancer, hearing impairment, and nursing home living increase the risk of severe frailty or death and should be considered when person‐centered care is planned for hospitalized older people.
Ali Vahedi, Maria Eriksdotter, Hege Ihle‐Hansen, Torgeir Bruun Wyller, Anne Rita Øksengård, Brynjar Fure   +5 more
wiley   +1 more source

Expert Consensus on the Management of Obesity in Older Adults (2026 Edition)

AGING MEDICINE, EarlyView.
This graphical abstract summarizes a safety‐first framework for managing obesity in older adults, with attention to age, functional status, comorbidities, and sarcopenia risk. Key assessments include BMI, waist measures, body fat percentage, skeletal muscle mass, and comprehensive geriatric evaluation. Management prioritizes reducing visceral fat while
Qi Pan, Lixin Guo
wiley   +1 more source