Results 21 to 30 of about 1,640,993 (346)

Elastin stabilization prevents impaired biomechanics in human pulmonary arteries and pulmonary hypertension in rats with left heart disease

Nature Communications, 2023
Pulmonary hypertension worsens outcome in left heart disease. Stiffening of the pulmonary artery may drive this pathology by increasing right ventricular dysfunction and lung vascular remodeling.
Mariya M. Kucherenko, Pengchao Sang, Juquan Yao, Tara Gransar, Saphala Dhital, Jana Grune, Szandor Simmons, Laura Michalick, Dag Wulsten, Mario Thiele, Orr Shomroni, Felix Hennig, Ruhi Yeter, Natalia Solowjowa, Gabriela Salinas, Georg N. Duda, Volkmar Falk, Naren R. Vyavahare, Wolfgang M. Kuebler, Christoph Knosalla   +19 more
doaj   +1 more source

The use of Macitentan in Fontan circulation: a case report

BMC Cardiovascular Disorders, 2017
Background The Fontan circulation, a result of a palliative procedure in patients with single systemic ventricles, is defined by chronically elevated pulmonary vascular resistance.
Polyvios Demetriades, Amir Aziz, Robin Condliffe, Sarah E. Bowater, Paul F. Clift   +4 more
doaj   +1 more source

Latent Pulmonary Vascular Disease May Alter the Response to Therapeutic Atrial Shunt Device in Heart Failure

Circulation, 2022
Background: In REDUCE LAP-HF II (A Study to Evaluate the Corvia Medical, Inc IASD System II to Reduce Elevated Left Atrial Pressure in Patients With Heart Failure), implantation of an atrial shunt device did not provide overall clinical benefit for ...
B. Borlaug, John Blair, M. Bergmann, H. Bugger, D. Burkhoff, L. Bruch, D. Celermajer, B. Claggett, J. Cleland, D. Cutlip, I. Dauber, J. Eicher, Qi Gao, T. Gorter, F. Gustafsson, C. Hayward, J. van der Heyden, G. Hasenfuss, S. Hummel, D. Kaye, J. Komtebedde, J. Massaro, J. Mazurek, S. McKenzie, S. Mehta, M. Petrie, M. Post, Ajith Nair, A. Rieth, F. Silvestry, S. Solomon, J. Trochu, D. V. van Veldhuisen, R. Westenfeld, M. Leon, Sanjiv J. Shah   +35 more
semanticscholar   +1 more source

Pulmonary hypertension due to left heart disease

European Respiratory Journal, 2019
Pulmonary hypertension (PH) is frequent in left heart disease (LHD), as a consequence of the underlying condition. Significant advances have occurred over the past 5 years since the 5th World Symposium on Pulmonary Hypertension in 2013, leading to a ...
J. Vachiéry, R. Tedford, S. Rosenkranz, M. Palazzini, I. Lang, M. Guazzi, G. Coghlan, I. Chazova, T. De Marco   +8 more
semanticscholar   +1 more source

Stem cell therapy in pulmonary hypertension: current practice and future opportunities

European Respiratory Review, 2023
Pulmonary hypertension (PH) is a progressive disease characterised by elevated pulmonary arterial pressure and right-sided heart failure. While conventional drug therapies, including prostacyclin analogues, endothelin receptor antagonists and ...
Ruixuan Zheng, Tingting Xu, Xinghong Wang, Lehe Yang, Jian Wang, Xiaoying Huang   +5 more
doaj   +1 more source

Cardiovascular pathology in patients with newly diagnosed tuberculosis and chronic obstructive pulmonary disease

Медицинский совет, 2021
Introduction. Chronic obstructive pulmonary disease and cardiovascular diseases (arterial hypertension, ischemic heart disease, chronic heart failure) are among the comorbid conditions that mutually aggravate each other.
N. V. Bagisheva, A. V. Mordyk, I. A. Viktorova, D. I. Trukhan   +3 more
doaj   +1 more source

Metabolic Syndrome Exacerbates Pulmonary Hypertension due to Left Heart Disease.

Circulation Research, 2019
RATIONALE Pulmonary hypertension (PH) due to left heart disease (PH-LHD), or Group2-PH, is the most prevalent form of PH worldwide. PH-LHD is often associated with metabolic syndrome (MetS).
Benoît Ranchoux, V. Nadeau, A. Bourgeois, S. Provencher, È. Tremblay, J. Omura, N. Côté, R. Abu-Alhayja’a, V. Dumais, R. Nachbar, L. Tastet, A. Dahou, S. Breuils-Bonnet, A. Marette, P. Pibarot, J. Dupuis, O. Boucherat, R. Paulin, S. Archer, S. Bonnet, F. Potus   +20 more
semanticscholar   +1 more source

Pulmonary Diseases and the Heart [PDF]

Circulation, 2007
The complex nature of interactions between the pulmonary and cardiovascular systems is becoming increasingly appreciated. Pulmonary vascular abnormalities are frequently present in patients with respiratory disorders, including chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, sarcoidosis, neuromuscular or chest wall disorders, and ...
MeiLan K, Han, Vallerie V, McLaughlin, Gerard J, Criner, Fernando J, Martinez   +3 more
openaire   +2 more sources

Assessment of reversibility in pulmonary arterial hypertension and congenital heart disease

Heart, 2018
Pulmonary arterial hypertension (PAH) in congenital heart disease (CHD) can be reversed by early shunt closure, but this potential is lost beyond a certain point of no return.
D. E. van der Feen, B. Bartelds, Rudolf A. de Boer, R. Berger   +3 more
semanticscholar   +1 more source

Management dilemmas in pulmonary arterial hypertension associated with congenital heart disease

Pulmonary Circulation, 2018
There are few randomised controlled data to guide management of patients with pulmonary arterial hypertension associated with congenital heart disease (PAH-CHD).
R. Condliffe, P. Clift, K. Dimopoulos, R.M.R. Tulloh   +3 more
doaj   +1 more source