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Incidence and outcomes of pulmonary hypertension in the Ireland

BMJ Open Respiratory Research, 2022
Introduction Pulmonary hypertension (PH) is a progressive disease of the pulmonary vasculature, which is characterised by premature morbidity and mortality.
Sarah Cullivan, Sean Gaine, Brian McCullagh, Denise Lennon, Salima Meghani, Caitriona Minnock   +5 more
doaj   +1 more source

Characteristics of chronic thromboembolic pulmonary hypertension in Ireland

Pulmonary Circulation, 2021
Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare and under‐recognised complication of acute pulmonary embolism. Information regarding the characteristics of CTEPH in Ireland is limited, and the aim of this retrospective cohort study was to
Sarah Cullivan, Ciara McCormack, Marissa O’Callaghan, Barry Kevane, Fionnuala NiAinle, Brian McCullagh, Sean P. Gaine   +6 more
doaj   +1 more source

Tolerability, safety and survival in patients with severe pulmonary arterial hypertension treated with intravenous epoprostenol (Veletri®): a prospective, 6-months, open label, observational, non-interventional study

Respiratory Research, 2023
Background Epoprostenol AS (Veletri®), a thermostable epoprostenol formulation, provides better drug stability and improved clinical use compared to previous epoprostenol formulations. This study aims to expand clinical experience in the use of Veletri®,
Julia Degering, Benjamin Egenlauf, Satenik Harutyunova, Nicola Benjamin, Amina Salkić, Panagiota Xanthouli, Christina A. Eichstaedt, Rebekka Seeger, Olivier Sitbon, Ekkehard Grünig   +9 more
doaj   +1 more source

Risk stratification and prognostic factors in patients with pulmonary arterial hypertension and comorbidities a cross-sectional cohort study with survival follow-up

Respiratory Research, 2020
Background The objective of this study was to analyze prognostic factors and risk stratification in patients with pulmonary arterial hypertension (PAH) and comorbidities.
Panagiota Xanthouli, Maria Koegler, Alberto M. Marra, Nicola Benjamin, Lukas Fischer, Christina A. Eichstaedt, Satenik Harutyunova, Christian Nagel, Ekkehard Grünig, Benjamin Egenlauf   +9 more
doaj   +1 more source

Prognostic meaning of right ventricular function and output reserve in patients with systemic sclerosis

Arthritis Research & Therapy, 2022
Background The objective of this study was to investigate the prognostic impact of right ventricular (RV) function at rest and during exercise in patients with systemic sclerosis (SSc) presenting for a screening for pulmonary hypertension (PH).
Panagiota Xanthouli, Julia Miazgowski, Nicola Benjamin, Ojan Gordjani, Benjamin Egenlauf, Satenik Harutyunova, Rebekka Seeger, Alberto M. Marra, Norbert Blank, Hanns-Martin Lorenz, Ekkehard Grünig, Christina A. Eichstaedt   +11 more
doaj   +1 more source

Prognostic impact of hypochromic erythrocytes in patients with pulmonary arterial hypertension

Respiratory Research, 2021
Background Iron deficiency affects up to 50% of patients with pulmonary arterial hypertension (PAH) but iron markers such as ferritin and serum iron are confounded by several non-disease related factors like acute inflammation and diet.
Panagiota Xanthouli, Vivienne Theobald, Nicola Benjamin, Alberto M. Marra, Anna D’Agostino, Benjamin Egenlauf, Memoona Shaukat, Cao Ding, Antonio Cittadini, Eduardo Bossone, Maria Kögler, Ekkehard Grünig, Martina U. Muckenthaler, Christina A. Eichstaedt   +13 more
doaj   +1 more source

Oxygenated hemoglobin as prognostic marker among patients with systemic sclerosis screened for pulmonary hypertension

Scientific Reports, 2023
Oxygenated hemoglobin (OxyHem) in arterial blood may reflect disease severity in patients with systemic sclerosis (SSc). The aim of this study was to analyze the predictive value of OxyHem in SSc patients screened for pulmonary hypertension (PH). OxyHem (
Panagiota Xanthouli, Ojan Gordjani, Nicola Benjamin, Franziska C. Trudzinski, Benjamin Egenlauf, Satenik Harutyunova, Alberto M. Marra, Nicklas Milde, Christian Nagel, Norbert Blank, Hanns-Martin Lorenz, Ekkehard Grünig, Christina A. Eichstaedt   +12 more
doaj   +1 more source

Glucocorticoids for treating paediatric pulmonary hypertension: A novel use for a common medication [PDF]

, 2017
Laboratory investigations have shown the role of inflammation in the pathogenesis of pulmonary hypertension and improvement after anti-inflammatory drugs.
Aggarwal, Manish, Grady, Ronald M
core   +2 more sources

Left main bronchus compression due to main pulmonary artery dilatation in pulmonary hypertension: two case reports [PDF]

, 2015
. Pulmonary arterial dilatation associated with pulmonary hypertension may result in significant compression of local structures. Left main coronary artery and left recurrent laryngeal nerve compression have been described.
Ariff, B, Davies, R, Gibbs, JS, Gin-Sing, W, Howard, L, Jaijee, SK, O'Regan, DP   +6 more
core   +1 more source

Transient but not genetic loss of miR-451 attenuates the development of pulmonary arterial hypertension [PDF]

, 2013
<b>Rationale:</b> MicroRNAs are small non-coding RNAs involved in the regulation of gene expression and have recently been implicated in the development of pulmonary arterial hypertension (PAH).
Baker, Andrew H., Dempsie, Yvonne, Grant, Jennifer S., MacLean, Margaret R., Morecroft, Ian, van Rooij, Eva   +5 more
core   +2 more sources