Results 21 to 30 of about 1,353,059 (301)

Transforming growth factor-beta receptor mutations and pulmonary arterial hypertension in childhood [PDF]

open access: yes, 2005
BACKGROUND: Pulmonary arterial hypertension (PAH) is a potentially fatal vasculopathy that can develop at any age. Adult-onset disease has previously been associated with mutations in BMPR2 and ALK-1.
Haworth, SG   +22 more
core   +1 more source

Right heart size and function significantly correlate in patients with pulmonary arterial hypertension – a cross-sectional study

open access: yesRespiratory Research, 2018
Background The objective of this study was to assess, whether right atrial (RA) and ventricular (RV) size is related to RV pump function at rest and during exercise in patients with pulmonary arterial hypertension (PAH).
Lukas Fischer   +12 more
doaj   +1 more source

Exploratory analysis of the neutrophil to lymphocyte ratio in patients with pulmonary arterial hypertension

open access: yesBMC Pulmonary Medicine, 2017
Background Chronic inflammation emerges as a feature of the pathogenesis of pulmonary arterial hypertension (PAH) in experimental models. Alterations of circulating cell subsets have been observed in patients with PAH.
Lars Harbaum   +9 more
doaj   +1 more source

Non-Invasive Pulmonary Artery Wave Intensity Analysis in Pulmonary Hypertension. [PDF]

open access: yes, 2015
Pulmonary wave reflections are a potential hemodynamic biomarker for pulmonary hypertension (PH) and can be analyzed using wave intensity analysis (WIA). In this study we used pulmonary vessel area and flow obtained using cardiac magnetic resonance (CMR)
Moledina, S   +17 more
core   +1 more source

Neurohormonal modulation in pulmonary arterial hypertension

open access: yes, 2021
Pulmonary hypertension is a fatal condition of elevated pulmonary pressures, complicated by right heart failure. Pulmonary hypertension appears in various forms; one of those is pulmonary arterial hypertension (PAH) and is particularly characterized by ...
de Man, Frances S.   +3 more
core   +1 more source

Distinct Platelet Ribonucleic Acid Signatures in Patients with Pulmonary Hypertension

open access: yes, 2022
Rationale: Pulmonary hypertension encompasses progressive disorders leading to right ventricular dysfunction and early death. Late detection is an important cause of poor clinical outcomes.
Smits, A Josien   +19 more
core   +1 more source

Impact of targeted pulmonary arterial hypertension therapies in severe pulmonary hypertension in chronic lung diseases

open access: yesERJ Open Research, 2023
Research questions Patients with severe pulmonary hypertension associated with chronic lung disease have a poor prognosis. Targeted pulmonary arterial hypertension therapies might improve exercise capacity and outcome, but there are no guidelines on ...
Romain Naud   +10 more
doaj   +1 more source

EXPRESS: Statement on imaging and pulmonary hypertension from the Pulmonary Vascular Research Institute (PVRI) [PDF]

open access: yes, 2019
Pulmonary hypertension is highly heterogeneous and despite treatment advances it remains a life shortening condition. There have been significant advances in imaging technologies, but despite evidence of their potential clinical utility practice remains
Swift, Andrew J.   +107 more
core   +1 more source

Pulmonary Hypertension [PDF]

open access: yesPulmonary Medicine, 2012
Pulmonary hypertension (PH), defined as elevated pulmonary artery pressure, is common in the general population and associated with increased mortality. Accordingly, physicians commonly encounter patients with dyspnea, exercise intolerance, and/or right heart failure who have elevated pulmonary artery systolic pressure (PASP) on echocardiography ...
Ilknur Basyigit   +4 more
openaire   +5 more sources

Temporal Trends in Diagnostic Hemodynamics and Survival of Patients with Pulmonary Hypertension: A Single-Center Study

open access: yesLife, 2023
Advances in the diagnosis and treatment of pulmonary hypertension (PH) have gradually improved the disease course. This retrospective cohort study aims to explore the diagnostic hemodynamic profile and survival of PH patients and their temporal changes ...
Georgios E. Papadopoulos   +12 more
doaj   +1 more source

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