Results 41 to 50 of about 667,198 (303)

Macitentan in daily clinical practice: A single centre, 1-year experience

open access: yesPulmonology, 2018
The effectiveness and safety of macitentan, a dual endothelin-receptor antagonist (ERA) approved for the treatment of pulmonary arterial hypertension (PAH), were shown in an extensive clinical trial oriented towards morbidity and mortality events.
S. Cadenas-Menéndez   +5 more
doaj   +3 more sources

Effects of novel muscarinic M3 receptor ligand C1213 in pulmonary arterial hypertension models. [PDF]

open access: yes, 2016
Pulmonary hypertension (PH) is a complex disease comprising a pathologic remodeling and thickening of the pulmonary vessels causing an after load on the right heart ventricle that can result in ventricular failure. Triggered by oxidative stress, episodes
Ahmed, Mohamed   +5 more
core   +2 more sources

Pulmonary Hypertension [PDF]

open access: yesPulmonary Medicine, 2012
Pulmonary hypertension (PH), defined as elevated pulmonary artery pressure, is common in the general population and associated with increased mortality. Accordingly, physicians commonly encounter patients with dyspnea, exercise intolerance, and/or right heart failure who have elevated pulmonary artery systolic pressure (PASP) on echocardiography ...
Ilknur Basyigit   +4 more
openaire   +5 more sources

Pulmonary hypertension associated with left-sided heart disease

open access: yesSwiss Medical Weekly, 2017
Pulmonary hypertension associated with left-sided heart disease (PH-LHD) is the most common type of pulmonary hypertension. In patients with left-sided heart disease, the presence of pulmonary hypertension is typically a marker of more advanced disease,
Micha T. Maeder   +5 more
doaj   +1 more source

Prospective clinical assessment of patients with pulmonary arterial hypertension switched from bosentan to macitentan (POTENT)

open access: yesPulmonary Circulation, 2022
Even though pulmonary arterial hypertension (PAH) remains an incurable disease, the combination of PAH‐specific therapies allowed treatment strategies to evolve from symptom‐based ones to others that aim to move patients to low‐risk conditions ...
Abdullah M. Aldalaan   +7 more
doaj   +1 more source

Pulmonary hypertension

open access: yesNature Reviews Disease Primers
Pulmonary hypertension encompasses a range of conditions directly or indirectly leading to elevated pressures within the pulmonary arteries. Five main groups of pulmonary hypertension are recognized, all defined by a mean pulmonary artery pressure of >20 mmHg: pulmonary arterial hypertension (rare), pulmonary hypertension associated with left-sided ...
Ana Mocumbi   +7 more
openaire   +3 more sources

The patient experience of pulmonary hypertension: a large cross-sectional study of UK patients

open access: yesBMC Pulmonary Medicine, 2019
Background Pulmonary Hypertension Association UK (PHA-UK) is the only charity in the UK especially for people affected by pulmonary hypertension (PH).
Iain Armstrong   +6 more
doaj   +1 more source

Hypochromic red cells as a prognostic indicator of survival among patients with systemic sclerosis screened for pulmonary hypertension

open access: yesArthritis Research & Therapy, 2023
Background Patients with systemic sclerosis (SSc) are frequently affected by iron deficiency, particularly those with pulmonary hypertension (PH). The first data indicate the prognostic importance of hypochromic red cells (% HRC) > 2% among patients with
Panagiota Xanthouli   +14 more
doaj   +1 more source

Insights into the pulmonary vascular complications of heart failure with preserved ejection fraction [PDF]

open access: yes, 2019
Pulmonary hypertension in the setting of heart failure with preserved ejection fraction (PH-HFpEF) is a growing public health problem that is increasing in prevalence.
Gladwin, Mark T.   +2 more
core   +1 more source

Pulmonary hypertension in chronic lung diseases: comparison to other pulmonary hypertension groups

open access: yesPulmonary Circulation, 2018
Group 3 pulmonary hypertension (PH) is a common complication of advanced chronic lung disease. Our hypothesis was that group 3 PH is associated with a more severe baseline presentation and a more severe prognosis compared to group 1 pulmonary arterial ...
Nader Chebib   +7 more
doaj   +1 more source

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