Results 51 to 60 of about 1,426,440 (199)

Pulmonary Hypertension and Weaning

, 2016
Pulmonary hypertension is a patophysiologic state of pulmonary circulation that mean pulmonary arterial pressure is measured as equal to or greater than 25 mmHg at rest via right heart cateterization.
Nedim Çekmen, Ceren Gunt
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Chemical and biological assessment of metal organic frameworks (MOFs) in pulmonary cells and in an acute in vivo model: relevance to pulmonary arterial hypertension therapy [PDF]

, 2017
Pulmonary arterial hypertension (PAH) is a progressive and debilitating condition. Despite promoting vasodilation, current drugs have a therapeutic window within which they are limited by systemic side effects.
Lickiss, PD, Barreira, B, Mitchell, JA, Kirkby, NS, Reed, DM, Ahmetaj-Shala, B, Freeman, GR, Yacoub, MH, Mohamed, NA, Morales-Cano, D, Chester, AH, Saleem, H, Tetley, TD, Gashaw, HH, Moreno, L, Davies, RP, Wort, SJ, George, PM, Freeman, Gemma R, Peter M. George, Paul D. Lickiss, Hime H. Gashaw, Wort, Stephen J, Yacoub, Magdi H, Saleem, Hira, George, Peter M, Kirkby, Nicholas S, Adrian H. Chester, Mohamed, Nura A, Ahmetaj-Shala, Blerina, Morales-Cano, Daniel, Blerina Ahmetaj‐Shala, Barreira, Bianca, Nura A. Mohamed, Laura Moreno, Lickiss, Paul D, Daniel Morales‐Cano, Daniel M. Reed, Davies, Robert P, Gashaw, Hime H, Stephen J. Wort, Gemma R. Freeman, Moreno, Laura, Robert P. Davies, Jane A. Mitchell, Reed, Daniel M, Mitchell, Jane A, Teresa D. Tetley, Chester, Adrian H, Hira Saleem, Magdi H. Yacoub, Tetley, Teresa D, Bianca Barreira, Nicholas S. Kirkby   +53 more
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Apelin and Pulmonary Hypertension [PDF]

Pulmonary Circulation, 2011
Pulmonary arterial hypertension (PAH) is a devastating disease characterized by pulmonary vasoconstriction, pulmonary arterial remodeling, abnormal angiogenesis and impaired right ventricular function. Despite progress in pharmacological therapy, there is still no cure for PAH.
Andersen, Charlotte Uggerhøj, Hilberg, Ole, Mellemkjær, Søren, Nielsen-Kudsk, Jens E, Simonsen, U; id_orcid 0000-0002-2169-7666   +4 more
openaire   +2 more sources

Right Ventricular Remodeling and Dysfunction in Obstructive Sleep Apnea: A Systematic Review of the Literature and Meta-Analysis

Canadian Respiratory Journal, 2017
Background. Recent studies have reported that obstructive sleep apnea (OSA) patients present alterations in right ventricular (RV) structure and function. However, large randomized controlled trials evaluating the impact of OSA on the right ventricle are
Abdirashit Maripov, Argen Mamazhakypov, Meerim Sartmyrzaeva, Almaz Akunov, Kubatbek Muratali uulu, Melis Duishobaev, Meerim Cholponbaeva, Akylbek Sydykov, Akpay Sarybaev   +8 more
doaj   +1 more source

Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood

, 2021
Idiopathic pulmonary arterial hypertension (IPAH) is a rare but fatal disease diagnosed by right heart catheterisation and the exclusion of other forms of pulmonary arterial hypertension, producing a heterogeneous population with varied treatment ...

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Significance of echocardiographic metrics including TRV and TAPSE/SPAP in mild haemodynamic pulmonary hypertension – data from EVIDENCE-PAH UK

Echo Research and Practice
Background The 2022 ESC/ERS guidelines redefined pulmonary hypertension (PH) as a mean pulmonary artery pressure (mPAP) >20 mmHg on right heart catheterisation (RHC).
Nina Karia, Daniel Murphy, Luke Howard, Martin Johnson, David G. Kiely, James Lordan, Colm McCabe, Joanna Pepke-Zaba, Daniel Knight, Vivek Muthurangu, J. Gerry Coghlan   +10 more
doaj   +1 more source

Noninvasive diagnostic modalities and prediction models for detecting pulmonary hypertension associated with interstitial lung disease: a narrative review

European Respiratory Review
Pulmonary hypertension (PH) is highly prevalent in patients with interstitial lung disease (ILD) and is associated with increased morbidity and mortality.
Alexandra Arvanitaki, Gerhard Paul Diller, Michael A. Gatzoulis, Colm McCabe, Laura C. Price, S. John Wort   +5 more
doaj   +1 more source

Advancing Clinical Trial Design in Pulmonary Hypertension [PDF]

, 2013
In pulmonary hypertension, as in many other diseases, there is a need for a smarter approach to evaluating new treatments. The traditional randomized controlled trial has served medical science well, but constrains the development of treatments for rare ...
D. Dunbar Ivy, Shen Xiao, Hsien Ming J. Hung, Xiao, Shen, Shien‐Chung Chow, Noreen R. Henig, Kawut, Steven M, Hung, Hsien Ming J, Grieve, Andy P, Stephen Dawe, Dawe, Stephen, Harnisch, Lutz O, Chow, Shien-Chung, Andy P. Grieve, Lutz O. Harnisch, Henig, Noreen R, Rahbar, Mohammad H, Steven M. Kawut, John Curram, Mohammad H. Rahbar, Curram, John, Ivy, D Dunbar, Wilkins, Martin R, Martin R. Wilkins   +23 more
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Pulmonary hypertension

Jornal Brasileiro de Pneumologia, 2023
Edson Marchiori1, Bruno Hochhegger2, Gláucia Zanetti1   +2 more
openaire   +5 more sources

Reduced gastrointestinal iron uptake in pulmonary arterial hypertension: a prospective cross-sectional study

Respiratory Research
Background Iron deficiency (ID) is common in patients with pulmonary arterial hypertension (PAH) and is associated with worse clinical outcomes. The etiology of ID in PAH is poorly understood. The aim of this study was to systematically determine whether
Luisa Repsold, Satenik Harutyunova, Ekkehard Grünig, Nicola Benjamin, Panagiota Xanthouli, Benjamin Egenlauf, Andreea Florea, Memoona Shaukat, Richard Sparla, Christina Mertens, Martina U. Muckenthaler, Christina A. Eichstaedt   +11 more
doaj   +1 more source