Results 71 to 80 of about 1,353,059 (301)

Reduced gastrointestinal iron uptake in pulmonary arterial hypertension: a prospective cross-sectional study

Respiratory Research
Background Iron deficiency (ID) is common in patients with pulmonary arterial hypertension (PAH) and is associated with worse clinical outcomes. The etiology of ID in PAH is poorly understood. The aim of this study was to systematically determine whether
Luisa Repsold, Satenik Harutyunova, Ekkehard Grünig, Nicola Benjamin, Panagiota Xanthouli, Benjamin Egenlauf, Andreea Florea, Memoona Shaukat, Richard Sparla, Christina Mertens, Martina U. Muckenthaler, Christina A. Eichstaedt   +11 more
doaj   +1 more source

Determinants of Body Mass Index in Early Systemic Sclerosis: Implications for Nutritional Risk Stratification

Arthritis Care &Research, EarlyView.
Objective Gastrointestinal (GI) involvement can lead to malnutrition in patients with systemic sclerosis (SSc). Body mass index (BMI) remains the most widely used marker to screen nutritional status. We aimed to identify predictors of lower BMI in patients with SSc. Methods Patients with SSc from a prospective US cohort meeting 2013 American College of
Ali Y. Ayla, Meng Zhang, Bingrui Chen, Claudia Pedroza, Brian Skaug, Maureen Mayes, Michael Hughes, Shervin Assassi, Zsuzsanna H. McMahan   +8 more
wiley   +1 more source

Noninvasive diagnostic modalities and prediction models for detecting pulmonary hypertension associated with interstitial lung disease: a narrative review

European Respiratory Review
Pulmonary hypertension (PH) is highly prevalent in patients with interstitial lung disease (ILD) and is associated with increased morbidity and mortality.
Alexandra Arvanitaki, Gerhard Paul Diller, Michael A. Gatzoulis, Colm McCabe, Laura C. Price, S. John Wort   +5 more
doaj   +1 more source

Association of Elevated Platelets and C‐Reactive Protein With Severe Disease and Poor Survival in Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.
Brian S. Lee, Shufeng Li, Srijana Davuluri, Jennifer Lee, Lorinda Chung   +4 more
wiley   +1 more source

Caregiver Perspectives on the Burden of Disease and Treatment in Uncontrolled Gout

Arthritis Care &Research, EarlyView.
Objective Uncontrolled gout (UG) refers to persistently elevated serum urate (SU) levels >6 mg/dL and ongoing gout symptoms despite use of urate‐lowering therapy (ULT). The objective of this study was to evaluate the burden associated with informal caregiving for individuals with UG.
Angelo Gaffo, Bhavisha Desai, Abiola Oladapo, Nana Kragh, Rebekah Zincavage, Brad Padilla, Naomi Schlesinger   +6 more
wiley   +1 more source

Right ventricular function in scleroderma-related pulmonary hypertension [PDF]

, 2008
SSc-associated pulmonary arterial hypertension (PAH) has a poorer prognosis than that of other types of pulmonary hypertension. Recent echocardiographic and haemodynamic studies suggest that right ventriculer (RV) pump function and filling ...
A. Vonk Noordegraaf, Vonk Noordegraaf, Anton Vonk, Vonk Noordegraaf, A., Naeije, R., Naeije, Robert, R. Naeije   +5 more
core   +1 more source

Nitric oxide activates AMPK by modulating PDE3A in human pulmonary artery smooth muscle cells

Physiological Reports, 2020
Phosphodiesterase 3 (PDE3), of which there are two isoforms, PDE3A and PDE3B, hydrolyzes cAMP and cGMP—cyclic nucleotides important in the regulation of pulmonary vascular tone.
Julie Dillard, Xiaomei Meng, Leif Nelin, Yusen Liu, Bernadette Chen   +4 more
doaj   +1 more source

The Development of Rheumatoid Arthritis–Specific Ambulatory Care–Sensitive Conditions: Results of a Consensus Process

Arthritis Care &Research, EarlyView.
Objective Ambulatory care–sensitive conditions (ACSCs) serve as indicators of access, quality, and performance of the health system. This study aimed to determine rheumatoid arthritis (RA)‐specific ACSCs for use in the evaluation of care system access and quality.
Kara Irwin, Candace H. Feldman, Claire E. H. Barber, Gabriel Fabreau, Jake Jennings, Scott Patten, Cheryl Barnabe, Inflammatory Arthritis‐Specific ACSC Consensus Process Working Group   +7 more
wiley   +1 more source

MnTBAP reverses pulmonary vascular remodeling and improves cardiac function in experimentally induced pulmonary arterial hypertension [PDF]

, 2020
Pulmonary arterial hypertension (PAH) is a life-threatening disease characterized by obstructed pulmonary vasculatures. Current therapies for PAH are limited and only alleviate symptoms.
Bogaard, Harm Jan, Pan, Xiaoke, Zhou, Q., Harm-Jan Bogaard, Xiao-Qing Sun, Robert Szulcek, Bogaard, Harm-Jan, Dijke, Peter Ten, Mar Orriols, Orriols, M., Peter ten Dijke, Goumans, Marie José, Sun, Xiao-Qing, Gomez-Puerto, Maria Catalina, Xiaoke Pan, Schalij, I., Sun, Xiao Qing, Goumans, M.J., Goumans, Marie Josè T.H., Szulcek, Robert, Orriols, Mar, Marie-José Goumans, Bogaard, H.J., Pan, X.K., Dijke, P. ten, Schalij, Ingrid, Qian Zhou, Sun, X.Q., Zhou, Qian, Ingrid Schalij, Gomez-Puerto, M.C., Maria Catalina Gomez-Puerto, Szulcek, R.   +32 more
core   +1 more source

Beyond Visual Scoring: Computational Computed Tomography Analysis for High‐Resolution Computed Tomography–Based Quantification of Interstitial Lung Disease in Inflammatory Rheumatic Disease

Arthritis Care &Research, EarlyView.
Interstitial lung disease (ILD) is a significant cause of morbidity and mortality in patients with inflammatory rheumatic disorders (IRDs). High‐resolution computed tomography (HRCT) is widely considered the gold standard for the noninvasive assessment of ILD; however, its interpretation is constrained by substantial interobserver variability and the ...
Alexander Pfeil, Tobias Hoffmann, Ulf Teichgräber, Diane Renz, Denise Beckmann, Gunter Wolf, Nicole Schadewaldt, Bianca Lassen‐Schmidt   +7 more
wiley   +1 more source