Results 91 to 100 of about 1,426,440 (199)

Unraveling AURKB as a potential therapeutic target in pulmonary hypertension using integrated transcriptomic analysis and pre-clinical studies

Cell Reports Medicine
Summary: Despite advances in treatment, the prognosis for patients with pulmonary arterial hypertension (PAH) remains dismal, highlighting the need for further therapeutic advances. By using RNA sequencing on pulmonary artery smooth muscle cells (PASMCs),
Sarah-Eve Lemay, Manon Mougin, Mélanie Sauvaget, Reem El Kabbout, Chanil Valasarajan, Keiko Yamamoto, Sandra Martineau, Andréanne Pelletier, Coralie Bilodeau, Yann Grobs, Alice Bourgeois, Charlotte Romanet, Sandra Breuils-Bonnet, Monica S. Montesinos, Min Lu, Huidong Chen, Mégan Gilbert, Charlie Théberge, François Potus, Soni Pullamsetti, Steeve Provencher, Sébastien Bonnet, Olivier Boucherat   +22 more
doaj   +1 more source

Ischemia-reperfusion injury with a model of porcine whole-blood ex-vivo lung perfusion

Frontiers in Transplantation
IntroductionOur objective was to model Ischemia-Reperfusion (IR) injuries by ex-vivo perfusion of porcine lungs with whole blood containing the inflammatory cells.MethodsLungs and whole blood were collected from 12 pigs and submitted to cold ischemia ...
Jean-Baptiste Menager, Jean-Baptiste Menager, Jean-Baptiste Menager, Julia Mercier, Julia Mercier, Justin Issard, Justin Issard, Justin Issard, Maria-Rosa Ghigna, Maria-Rosa Ghigna, Maria-Rosa Ghigna, Jeanne Tran Van Nhieu, Benoit Decante, Benoit Decante, Julien Guihaire, Julien Guihaire, Elie Fadel, Elie Fadel, Elie Fadel, Fabrice Antigny, Fabrice Antigny, Olaf Mercier, Olaf Mercier, Olaf Mercier   +23 more
doaj   +1 more source

Pulmonary hypertension: diagnostic and therapeutic challenges

, 2015
Isabel S Bazan, Wassim H Fares Department of Internal Medicine, Section of Pulmonary, Critical Care and Sleep Medicine, Yale University, New Haven, CT, USA Abstract: Pulmonary hypertension (PH) is a hemodynamic and pathophysiologic state that can be ...
Bazan IS, Fares WH
core  

Dasatinib‐Induced Pulmonary Arterial Hypertension in Chronic Myeloid Leukaemia: A Case Report and Literature Review

Respirology Case Reports
Dasatinib, a second‐generation tyrosine kinase inhibitor used for treating chronic myeloid leukaemia (CML), is associated with rare but significant adverse effects, including pulmonary arterial hypertension.
Sathish Krishnan, Sashi Adigopula
doaj   +1 more source

Protein biomarkers in pulmonary arterial hypertension: advances, clinical relevance, and translational challenges

Journal of Translational Medicine
Pulmonary arterial hypertension (PAH) is a progressive and life-threatening disease characterized by pulmonary vasoconstriction and right ventricular dysfunction.
Yanqin Niu, Jinglin Tian, Steeve Provencher, Sebastien Bonnet, Olivier Boucherat, François Potus, Deming Gou   +6 more
doaj   +1 more source

Pulmonary hypertension [PDF]

Canadian Journal of Cardiology, 2010
Benjamin, Hibbert, Rebecca, Hibbert, Trevor, Simard, Carole, Dennie, Edward, O'Brien   +4 more
openaire   +2 more sources

Pulmonary Hypertension

Japanese Circulation Journal, 1975
openaire   +4 more sources

Pulmonary hypertension in Switzerland: treatment and clinical course.

, 2008
The prognosis of pulmonary hypertension (PH), especially idiopathic pulmonary arterial hypertension (IPAH), has improved during the recent years. The Swiss Registry for PH represents the collaboration of the various centres in Switzerland dealing with PH
Tamm, M., Ulrich, S., Speich, R., Domenighetti, G., Aubert, J.D., Dorschner, L., Fischler, M., Nicod, L., Rochat, T.   +8 more
core  

Pulmonary Hypertension Associated with Stenosis of the Right Pulmonary Artery Branch in a Dog

A 10-year-old male miniature dachshund dog was referred to our hospi tal for cough and dyspnea. Two-dimensional echocardiography revealed pulmonary hypertension with an echo-free circle structure adjacent to the dorsal side of the left atrium.
Takuya MATSUKAWA, Takehito MORITA, Yoshiaki HIKASA, Nagi TOMITA   +3 more
core   +1 more source

PET Imaging in Pulmonary Hypertension. [PDF]

Arterioscler Thromb Vasc Biol
van Leent MMT, St Hillaire T, Sivalokanathan S, Morita H, Robson PM, Ishikawa K, Trivieri MG.   +6 more
europepmc   +1 more source