Results 151 to 160 of about 104,967 (312)
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT This study explored the therapeutic efficacy of oxymatrine (OMT, C15H24N2O2) in a murine model of cigarette smoke (CS)‐induced chronic obstructive pulmonary disease (COPD) and elucidated its underlying mechanisms. A COPD model was established in mice through prolonged exposure to CS, followed by intraperitoneal administration of OMT (50 mg/kg)
Shuang Zhou, Ju‐Xiang Zhu, Jing Li
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Pediatric asthma is a common chronic airway inflammatory disease, where accurate assessment of disease severity and prognosis prediction is crucial for treatment decisions. Currently, there is a lack of precise and effective biomarkers.
Xu Yang +5 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Airway epithelial injury plays a critical role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Mitochondrial dysfunction is implicated in this injury, while the underlying mechanism remains incompletely understood. RNA sequencing was conducted to identify key genes involved in mitochondrial dysfunction in airway epithelial
Hu Shan +9 more
wiley +1 more source
Inhaled glucocorticosteroids in treatment of chronic obstructive pulmonary disease/
, 2018 А. Г. Романовских +2 more
openalex +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Lung injury is a common complication in critical sepsis. PRMT5 is implicated in endothelial inflammation and lung diseases, but its role in sepsis‐associated lung injury remains unclear. This study collected clinical sepsis samples and detected the mRNA expression of PRMT5.
Bo Wang, Zhen Ge, Fei‐Xiang Chen
wiley +1 more source
Economic Evaluation of Tobramycin Inhalation Powder for the Treatment of Chronic Pulmonary Pseudomonas aeruginosa Infection in Patients with Cystic Fibrosis [PDF]
, 2017 Srilekha Panguluri +3 more
openalex +1 more source
Inflammatory Markers Stratify Surgical Outcomes in Pediatric Airway Reconstruction
The Laryngoscope, EarlyView.ABSTRACT Objectives Red blood cell distribution width (RDW) predicts surgical success in adult patients undergoing open airway reconstruction for laryngotracheal stenosis, but similar biomarkers in pediatrics remain unidentified. This study identifies predictors of outcomes in pediatric patients undergoing triple endoscopy or surgical airway ...
Nomongo Dorjsuren +5 more
wiley +1 more source
A Novel Murine Model of Acute Laryngeal Injury After Intubation
The Laryngoscope, EarlyView.This study describes a novel murine model of acute laryngeal injury (ALgI) after intubation. Chemomechanical injury was performed to the posterior glottis of adult mice using a bleomycin‐dipped wire brush under endoscopic guidance, resulting in reduced glottic mobility, increased posterior glottic thickness, and increased collagen expression. This safe,
Ruth J. Davis +4 more
wiley +1 more source