Results 31 to 40 of about 164,448 (358)

The effects of different inhalation therapies on less symptomatic chronic obstructive pulmonary disease patients in a Chinese population: a real-world study

Annals of Medicine, 2023
Background The Global Initiative for Chronic Obstructive Lung Disease (GOLD) document suggests that patients with chronic obstructive pulmonary disease (COPD) should be divided into a less symptomatic group. Moreover, single-inhaled drugs are recommended
Qing Song, Ling Lin, Aiyuan Zhou, Wei Cheng, Cong Liu, Yating Peng, Zijing Zhou, Yuqin Zeng, Dingding Deng, Dan Liu, Zhiping Yu, Yan Chen, Shan Cai, Ping Chen   +13 more
doaj   +1 more source

Assessment of Inhalation Technique in Clinical and Functional Control of Asthma and Chronic Obstructive Pulmonary Disease

Acta Médica Portuguesa, 2015
Introduction: Chronic obstructive pulmonary disease and asthma affect almost 300 million individuals. Inhaled therapy is often associated with technical errors reducing efficacy and compliance.
Tiago Maricoto, Luís Vaz Rodrigues, Gilberto Teixeira, Carla Valente, Lília Andrade, Alcina Saraiva   +5 more
doaj   +1 more source

Inhalation characteristics of asthma patients, COPD patients and healthy volunteers with the Spiromax® and Turbuhaler® devices: a randomised, cross-over study. [PDF]

, 2015
BACKGROUND: Spiromax® is a novel dry-powder inhaler containing formulations of budesonide plus formoterol (BF). The device is intended to provide dose equivalence with enhanced user-friendliness compared to BF Turbuhaler® in asthma and chronic ...
A Hardwell, AH Boer de, AR Clark, BL Laube, Dinesh Saralaya, EF Juniper, F Lavorini, GM Hawksworth, H Chrystyn, H Chrystyn, H Chrystyn, H Chrystyn, Harold Hosker, Henry Chrystyn, JL Rau, JP Koning de, KR Chapman, L Bentur, ME Broeders, ME Broeders, MH Dewar, ML Everard, PH Brown, Philip Chetcuti, RA Al-Showair, V Giraud, W Azouz, W Azouz, Wahida Azouz, WE Kamin, WM Nsour   +30 more
core   +1 more source

The role of surface charge in the interaction of nanoparticles with model pulmonary surfactants [PDF]

Soft Matter 14, 5764-5774 (2018), 2018
Inhaled nanoparticles traveling through the airways are able to reach the respiratory zone of the lungs. In such event, the incoming particles first enter in contact with the liquid lining the alveolar epithelium, the pulmonary surfactant. The pulmonary surfactant is composed of lipids and proteins that are assembled into large vesicular structures ...
arxiv   +1 more source

Novel devices for individualized controlled inhalation can optimize aerosol therapy in efficacy, patient care and power of clinical trials

European Journal of Medical Research, 2009
In the treatment of pulmonary diseases the inhalation of aerosols plays a key role - it is the preferred route of drug delivery in asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis.
Fischer A, Stegemann J, Scheuch G, Siekmeier R   +3 more
doaj   +1 more source

Inhalation and deposition of spherical and pollen particles after middle turbinate resection in a human nasal cavity [PDF]

Respiratory Physiology & Neurobiology Volume 294, December 2021, 103769, 2021
Middle turbinate resection significantly alters the anatomy and redistributes the inhaled air. The superior half of the main nasal cavity is opened up, increasing accessibility to the region. This is expected to increase inhalation dosimetry to the region during exposure to airborne particles.
arxiv   +1 more source

Improved ventricular function during inhalation of PGI(2) aerosol partly relies on enhanced myocardial contractility [PDF]

, 2005
Inhaled prostacyclin (PGI(2)) aerosol induces selective pulmonary vasodilation. Further, it improves right ventricular ( RV) function, which may largely rely on pulmonary vasodilation, but also on enhanced myocardial contractility.
B. Zwissler, Burghuber OC, C. Hofstetter, E. Thein, F. Meisner, G. Kemming, H. Kisch-Wedel, Hardy C, Hoegl S, Holt JP, Kass D, Kieler JN, Kisch-Wedel H, M. Flondor, Maughan WL, Metsa KT, Pavlovic M, Roberts AM, S. Bruhn, Task, van der Velde ET, van Heerden PV, W. Kreyling, Welte M, Zwissler B   +24 more
core   +1 more source

Inhaled Therapy in Respiratory Disease: The Complex Interplay of Pulmonary Kinetic Processes

Canadian Respiratory Journal, 2018
The inhalation route is frequently used to administer drugs for the management of respiratory diseases such as asthma or chronic obstructive pulmonary disease.
Jens Markus Borghardt, Charlotte Kloft, Ashish Sharma   +2 more
doaj   +1 more source

Performance of Dry Powder Inhalers with Single Dosed Capsules in Preschool Children and Adults Using Improved Upper Airway Models

Pharmaceutics, 2014
The pulmonary administration of pharmaceutical aerosols to patients is affected by age-dependent variations in the anatomy of the upper airways and the inhalation pattern.
Sandra Lindert, Antje Below, Joerg Breitkreutz   +2 more
doaj   +1 more source

Searching the ideal inhaled vasodilator: From nitric oxide to prostacyclin [PDF]

, 2002
Today, the technique to directly administer vasodilators via the airway to treat pulmonary hypertension and to improve pulmonary gas exchange is widely accepted among clinicians.
Habler, Oliver, Kemming, Gregor, Kisch-Wedel, Hille, Kleen, Martin, Welte, M., Zwissler, Bernhard   +5 more
core   +1 more source