Results 271 to 280 of about 4,104,503 (378)
ATS Core Curriculum 2017: Part II. Pediatric Pulmonary Medicine. [PDF]
Moore PE+22 more
europepmc +1 more source
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang+10 more
wiley +1 more source
Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications
HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang+5 more
wiley +1 more source
RNA-seq in Pulmonary Medicine: How Much Is Enough? [PDF]
Ray M+13 more
europepmc +1 more source
As a plant‐derived flavonoid, apigenin directly targets PRDX6 to inhibit its PLA2 activity, blocking HSPA8 activation and disturbing its interactions with ATM and p38MAPK in senescent cells. By dampening wide spectrum expression of the SASP, apigenin prevents loss of tissue homeostasis, improves organ function, and alleviates multiple age‐related ...
Hongwei Zhang+10 more
wiley +1 more source
Respiratory medical quality control system construction in China
Yi‐Xuan Liao+6 more
doaj +1 more source
Textbook of pulmonary and critical care medicine by Dr. S. K. Jindal
BharatBhushan Sharma, Virendra Singh
openalex +1 more source