Results 81 to 90 of about 963,916 (300)

Repurposing of medications for pulmonary arterial hypertension

, 2020
This manuscript on drug repurposing incorporates the broad experience of members of the Pulmonary Vascular Research Institute’s Innovative Drug Development Initiative as an open debate platform for academia, the pharmaceutical industry and regulatory ...
Spiekerkoetter, Edda, Bogaard, Harm Jan, Toshner, Mark, Georg Hansmann, Edda Spiekerkoetter, Harm Bogaard, Hansmann, Georg, Kurt W. Prins, Sylvia Nikkho, Nikkho, Sylvia, Prins, Kurt W., Mark Toshner   +11 more
core   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Chronic thromboembolic pulmonary hypertension from the perspective of patients with pulmonary embolism

, 2018
Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare but feared long-term complication of acute pulmonary embolism (PE), although CTEPH may occur in patients with no history of symptomatic venous thromboembolism.
M. Delcroix, Klok, F A, Bogaard, H.J., Delcroix, M., Bogaard, H J, Delcroix, M, Klok, F.A., F.A. Klok, H.J. Bogaard   +8 more
core   +1 more source

Combined pulmonary fibrosis and emphysema and idiopathic pulmonary fibrosis in non-small cell lung cancer: impact on survival and acute exacerbation [PDF]

, 2019
BACKGROUND: In non-small cell lung cancer (NSCLC) patients, concomitant idiopathic pulmonary fibrosis (IPF) and emphysema (CPFE) are independently related to poor survival. CPFE is a condition with features of both pulmonary fibrosis and emphysema. Here,
문성우, 김승섭, 장준, 박무석, 심효섭, 김영삼, 이상훈   +6 more
core   +1 more source

Clinical Characteristics of Chronic Obstructive Pulmonary Disease in Female Patients: Findings from a KOCOSS Cohort

International Journal of COPD, 2020
Joon Young Choi,1,* Shin Young Kim,2,* Jae Ha Lee,3 Yong Bum Park,4 Yee Hyung Kim,5 Soo-Jung Um,6 Ki Suck Jung,7 Kwang Ha Yoo,8 Seoung Ju Park,9 Hyoung Kyu Yoon10 1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Incheon
Choi JY, Kim SY, Lee JH, Park YB, Kim YH, Um SJ, Jung KS, Yoo KH, Park SJ, Yoon HK   +9 more
doaj  

Mortality from COVID-19 in Patients with COPD: A US Study in the N3C Data Enclave

International Journal of COPD, 2021
Daniel Meza, Basil Khuder, Joseph I Bailey, Sharon R Rosenberg, Ravi Kalhan, Paul A Reyfman Northwestern University, Feinberg School of Medicine, Division of Pulmonary and Critical Care Medicine, Chicago, IL, USACorrespondence: Paul A ReyfmanNorthwestern
Meza D, Khuder B, Bailey JI, Rosenberg SR, Kalhan R, Reyfman PA   +5 more
doaj  

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Interleukin-6 and airflow limitation in chemical warfare patients with chronic obstructive pulmonary disease [PDF]

Objectives: Chronic obstructive pulmonary disease (COPD) is one of the main late complications of sulfur mustard poisoning. The aim of this study was to evaluate serum levels of interleukin (IL)-6 in war veterans with pulmonary complications of sulfur ...
خواجه دلوئی, محمد, Shahrzad Lari, توحیدی, محمد, آیت اللهی, حسین, محمدزاده لاری, شهرزاد, قبادی مراللو, حسن, عطاران, داود, بصیری, رضا, قانعی, مصطفی   +8 more
core   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

MnTBAP reverses pulmonary vascular remodeling and improves cardiac function in experimentally induced pulmonary arterial hypertension

, 2020
Pulmonary arterial hypertension (PAH) is a life-threatening disease characterized by obstructed pulmonary vasculatures. Current therapies for PAH are limited and only alleviate symptoms.
Bogaard, Harm Jan, Pan, Xiaoke, Zhou, Q., Harm-Jan Bogaard, Xiao-Qing Sun, Robert Szulcek, Bogaard, Harm-Jan, Dijke, Peter Ten, Mar Orriols, Orriols, M., Peter ten Dijke, Goumans, Marie José, Sun, Xiao-Qing, Gomez-Puerto, Maria Catalina, Xiaoke Pan, Schalij, I., Sun, Xiao Qing, Goumans, M.J., Goumans, Marie Josè T.H., Szulcek, Robert, Orriols, Mar, Marie-José Goumans, Bogaard, H.J., Pan, X.K., Dijke, P. ten, Schalij, Ingrid, Qian Zhou, Sun, X.Q., Zhou, Qian, Ingrid Schalij, Gomez-Puerto, M.C., Maria Catalina Gomez-Puerto, Szulcek, R.   +32 more
core   +1 more source