Results 101 to 110 of about 114,018 (252)

A Novel Murine Model of Acute Laryngeal Injury After Intubation

open access: yesThe Laryngoscope, EarlyView.
This study describes a novel murine model of acute laryngeal injury (ALgI) after intubation. Chemomechanical injury was performed to the posterior glottis of adult mice using a bleomycin‐dipped wire brush under endoscopic guidance, resulting in reduced glottic mobility, increased posterior glottic thickness, and increased collagen expression. This safe,
Ruth J. Davis   +4 more
wiley   +1 more source

Immunosuppression and Surgery‐Free Interval in Granulomatosis With Polyangiitis Airway Stenosis

open access: yesThe Laryngoscope, EarlyView.
Subglottic and tracheal stenosis are severe manifestations of granulomatosis with polyangiitis (GPA) that often require both endoscopic intervention and systemic immunosuppression. Rituximab may help stabilize GPA‐related airway disease by prolonging the interval between endoscopic procedures and delaying relapse.
Sydney J. Torres   +6 more
wiley   +1 more source

CT‐Based Comparison of Tracheostomy Placement Accuracy: Open Versus Percutaneous Approaches

open access: yesThe Laryngoscope, EarlyView.
This study provides the first objective CT‐based comparison of tracheostomy placement accuracy between open surgical and percutaneous techniques in 503 patients. Both methods achieved comparable stoma positioning relative to the cricoid cartilage, while patient factors and surgeon expertise had a greater impact on placement accuracy than the surgical ...
Emad E. Khoury   +4 more
wiley   +1 more source

Mesna in Otologic Surgery: Efficacy and Safety—A Scoping Review

open access: yesThe Laryngoscope, EarlyView.
PRISMA flow diagram indicating the process of systematic inclusion and exclusion of articles. ABSTRACT Objective Mesna (Sodium 2‐mercaptoethanesulfonate) is widely used as a mucolytic agent and uroprotective agent. Recently, its disulfide bond‐breaking property has been applied in otologic surgery to facilitate safer dissection of cholesteatoma and ...
Kevork H. Atamian   +4 more
wiley   +1 more source

The Patient Perspective of Living With Recurrent Respiratory Papillomatosis

open access: yesThe Laryngoscope, EarlyView.
This study was conducted to better understand the perspectives and real‐world impact of the disease burden on patients diagnosed with recurrent respiratory papillomatosis (RRP) and caregivers who experience the disease daily. RRP results in clinical, financial, and psychosocial burdens. Increased public awareness of human papillomavirus (HPV) infection
Sara I. Pai   +7 more
wiley   +1 more source

Airway Involvement in Conradi–Hünermann–Happle Syndrome: A Novel Clinical Manifestation

open access: yesThe Laryngoscope, EarlyView.
We report the first documented case of airway involvement in Conradi–Hünermann–Happle syndrome (CDPX2), an X‐linked dominant form of chondrodysplasia punctata caused by pathogenic variants in EBP. A 2‐month‐old female with genetically confirmed CDPX2 developed severe subglottic stenosis and persistent respiratory distress requiring CPAP; cross ...
Enrique G. Villarreal   +3 more
wiley   +1 more source

Systemic Immunosuppression to Reduce Surgical Intervention in ANCA‐Negative Subglottic Stenosis

open access: yesThe Laryngoscope, EarlyView.
Idiopathic subglottic stenosis (iSGS) typically follows an indolent course managed with surgical dilatation, though a subset demonstrates aggressive, recurrent disease. In this retrospective cohort study, systemic immunosuppression significantly prolonged inter‐dilation intervals in both granulomatosis with polyangiitis‐associated SGS and an “atypical”
Guy Benshetrit   +5 more
wiley   +1 more source

Resolution of Levodopa/Dopa‐Decarboxylase Inhibitor—Associated Microscopic Colitis with Subcutaneous Foslevodopa/Foscarbidopa: A Case Series and Review of the Literature

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Microscopic colitis (MC) typically presents with chronic, non‐bloody watery diarrhea. Diagnosis requires endoscopy with colonic mucosal biopsies. The etiology is multifactorial, with several medications implicated, although only a few cases have been attributed to oral levodopa/dopa‐decarboxylase inhibitor (LDDCI) therapy.
Romana Hintner   +10 more
wiley   +1 more source

Advances and Prospects of Stereotactic Radiosurgery and Stereotactic Ablative Body Radiotherapy: Evolving Paradigms in Precision Oncology

open access: yesMed Research, EarlyView.
The graphical abstract outlines the progressive development and impact of stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). Technological Evolution illustrates the transition from brachytherapy with single‐dose, LDR/HDR schedules to fractionated radiotherapy, three‐dimensional conformal radiotherapy (3DCRT) and Gamma Knife ...
Jing Zhang   +10 more
wiley   +1 more source

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