Results 121 to 130 of about 73,726 (337)

Pulmonary ischemia and surfactant in the neonatal lung [PDF]

open access: bronze, 1971
Ronald S. Bloom   +5 more
openalex   +1 more source

Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review

open access: yesAdvanced Science, EarlyView.
This paper analyzes RAGE ligand‐binding mechanisms and signaling, proposing intervention strategies targeting these interactions. It emphasizes dietary polyphenols, polysaccharides, and terpenoids delivered via functional foods for anti‐aging. These compounds offer long‐term, safe intervention through dietary supplementation, providing dual nutritional
Qian Wu   +7 more
wiley   +1 more source

A Single‐Component Adhesive Sponge Based on Blood‐Triggered and Autopenetrative Adhesion for Robust Vascular Closure

open access: yesAdvanced Science, EarlyView.
This study presents MonoSeal, a single‐component adhesive sponge powered by the novel Autopenetrative Adhesion (APA) mechanism. Unlike traditional adhesives, which require external stimuli, APA enables strong tissue adhesion under dynamic, high‐pressure bleeding conditions. MonoSeal's ability to autonomously seal large‐size arterial defects underscores
Rong Wang   +15 more
wiley   +1 more source

A mouse model of lung ischemia–reperfusion injury with reversible left hilar entrapment

open access: yesAnimal Models and Experimental Medicine, EarlyView.
A Novel Reversible Left Hilar Entrapment Model for Mouse Lung Ischemia‐Reperfusion Injury with Visual Tracheal Intubation and Live Knot Technique. Abstract Lung ischemia–reperfusion injury (LIRI), an acute lung injury syndrome triggered by lung transplantation or distal organ ischemia, has long been a difficult and hot issue in clinical research.
GuangDong Weng   +4 more
wiley   +1 more source

A novel alveolar Krebs cycle-triggered CO2 sensing mechanism regulates regional pulmonary ventilation. [PDF]

open access: yes, 2011
Pulmonary perfusion disorders provoke atelectasis in order to minimize ventilation/perfusion mismatch. However, the underlying mechanisms remain unknown.
Alwin Goetz   +7 more
core   +1 more source

Research advances in dysphagia animal models

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This review systematically summarizes the establishment, evaluation, and detection of dysphagia animal models in stroke, Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS) in three kinds of experimental animals (including rodents, nonhuman primates, and other mammals), providing a basis for the selection of appropriate animal models of ...
Junhui Bai   +5 more
wiley   +1 more source

Diosgenin ameliorates silica‐induced tuberculosis in rats

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Silicosis increases susceptibility to tuberculosis due to impaired macrophage function and oxidative stress. This study demonstrates that diosgenin, a steroidal saponin, significantly inhibits Mycobacterium smegmatis (IC₅₀ = 0.006 μg/mL), reduces lung fibrosis, and restores antioxidant enzyme levels (↑SOD, ↑CAT, ↓MDA) in silica‐exposed rats ...
Williams Asamoah Adu   +5 more
wiley   +1 more source

Antimicrobial Behavior of Simvastatin‐Loaded Solution Blow‐Spun PLA/PEO/HA Scaffolds

open access: yesJournal of Applied Polymer Science, EarlyView.
Schematic for fiber spinning. ABSTRACT The development of three‐dimensional scaffolds with suitable biological properties is of crucial importance in bone repair. Incorporating antimicrobial functionality into these scaffolds can further enhance their clinical efficacy by helping prevent infections, particularly in patients undergoing orthopedic ...
João P. A. Caribé   +17 more
wiley   +1 more source

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