Results 161 to 170 of about 73,571 (236)

HOXA5 Suppresses NEK7‐Mediated Alveolar Epithelial Pyroptosis in Acute Lung Injury by Transcriptionally Inhibiting KAT2A

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Alveolar epithelial cell pyroptosis exacerbates inflammation and tissue damage by releasing inflammatory mediators, thereby promoting the development of acute lung injury (ALI). However, the fundamental mechanism underlying alveolar epithelial cell pyroptosis in ALI has not yet been elucidated. Lipopolysaccharide (LPS) was used to simulate ALI
Lei Wang, Heng Fan, Qi Wang, Cheng‐Jie Jiang, Dan‐Hui Li, Ji‐Hui Ye   +5 more
wiley   +1 more source

[Retracted] Mechanism of IL‑8‑induced acute lung injury through pulmonary surfactant proteins A and B. [PDF]

Exp Ther Med
Yang Y, Li Q, Tan F, Zhang J, Zhu W.
europepmc   +1 more source

Pulmonary Surfactant Proteins Are Inhibited by Immunoglobulin A Autoantibodies in Severe COVID-19. [PDF]

Am J Respir Crit Care Med, 2023
Sinnberg T, Lichtensteiger C, Ali OH, Pop OT, Jochum AK, Risch L, Brugger SD, Velic A, Bomze D, Kohler P, Vernazza P, Albrich WC, Kahlert CR, Abdou MT, Wyss N, Hofmeister K, Niessner H, Zinner C, Gilardi M, Tzankov A, Röcken M, Dulovic A, Shambat SM, Ruetalo N, Buehler PK, Scheier TC, Jochum W, Kern L, Henz S, Schneider T, Kuster GM, Lampart M, Siegemund M, Bingisser R, Schindler M, Schneiderhan-Marra N, Kalbacher H, McCoy KD, Spengler W, Brutsche MH, Maček B, Twerenbold R, Penninger JM, Matter MS, Flatz L.   +44 more
europepmc   +1 more source

Congestion, decongestion, renal function and diuretics in (ESC) heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 730-732, April 2025.
Jan Biegus, Piort Gajewski, Piotr Ponikowski   +2 more
wiley   +1 more source

Efficacy and Safety of IncobotulinumtoxinA for Treatment of Sialorrhea: A Multicenter, Phase 3 Study in Japan

Movement Disorders Clinical Practice, EarlyView.
This study demonstrated significant treatment efficacy and safety of incobotulinumtoxinA injection in Japanese patients with chronic sialorrhea caused by Parkinson's disease and other neurological conditions. Suppression of salivary secretion and improvement in drooling symptoms were also observed throughout 48 weeks.
Nobutaka Hattori, Yohei Mukai, Noriko Nishikawa, Kazuko Hasegawa, Masahiko Tomiyama, Yasuyoshi Kimura, Yoshio Tsuboi, Ryosuke Takahashi, Ryota Nakamura, Yuishin Izumi, Hirohisa Watanabe, Morinobu Seki, Kenji Sekiguchi, Shohei Tateishi, Yusaku Matsushita, Yusaku Nakamura   +15 more
wiley   +1 more source

Novel opportunities from bioimaging to understand the trafficking and maturation of intracellular pulmonary surfactant and its role in lung diseases. [PDF]

Front Immunol, 2023
Garcia MJ, Amarelle L, Malacrida L, Briva A.   +3 more
europepmc   +1 more source

Diversity and assembly of the microbiome of a leguminous plant along an urbanization gradient

Oikos, EarlyView.
Interactions between plants and bacterial communities are essential for host physiology and broader ecosystem functioning, but plant–microbiome interactions can be disrupted by environmental change like urbanization. Here, we evaluated how urbanization affected the diversity and assembly of soil and white clover Trifolium repens microbiome communities.
David Murray‐Stoker, Laura Rossi, Marc T. J. Johnson   +2 more
wiley   +1 more source

The pristine unused pulmonary surfactant isolated from human amniotic fluid forms highly condensed interfacial films. [PDF]

Physiol Rep
Castillo-Sánchez JC, Collada A, Batllori-Badia E, Galindo A, Cruz A, Pérez-Gil J.   +5 more
europepmc   +1 more source

A Unified Whole Lung PBK Model for Inhalational Uptake of Gases and Aerosols in Men

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Assessing the risk or benefit of an inhaled substance is challenging due to the variety of forms it can take (gas, vapor, particle, or droplet) and the complex biological processes involved in its uptake and retention. Physiologically based kinetic (PBK) models offer an alternative to in vivo experiments.
Norman Nowak, Sylvia E. Escher, Katharina Schwarz   +2 more
wiley   +1 more source

Safety and efficacy of pulmonary surfactant therapy for acute respiratory distress syndrome in children: a systematic review and meta-analysis. [PDF]

BMC Pulm Med
Ren X, Jiang Q, Wang L, Yuan X, Chen D, Xu G.   +5 more
europepmc   +1 more source