Results 311 to 320 of about 74,761 (355)
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Rapid determination of pulmonary surfactant
American Journal of Obstetrics and Gynecology, 1972Abstract Although the importance of the lecithin/sphingomyelin ratio in amniotic fluid (Gluck test) has been widely accepted as an accurate means of predicting fetal lung maturity, the test is not widely available. The importance of certain steps in the test as originally described has been ignored in some of the recent rapid tests reported for ...
Dale E. van Wormer, Donald Armstrong
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Calcium interactions in pulmonary surfactant
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1984The surfactant properties of natural bovine pulmonary surfactant, its lipid extracts and acetone precipitates of lipid extracts have been examined with an artificial alveolus model, the pulsating-bubble surfactometer. At bulk concentrations of 0.4% (wt./vol.) phospholipid in saline, all three preparations exhibited surfactant activity, i.e., were ...
Fred Possmayer, Marnie J. Weber
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The Pulmonary Collectins and Surfactant Metabolism
Annual Review of Physiology, 2001▪ Abstract  Lung surfactant covers and stabilizes a large, delicate surface at the interface between the host and the environment. The surfactant system is placed at risk by a number of environmental challenges such as inflammation, infection, or oxidant stress, and perhaps not surprisingly, it demonstrates adaptive changes in metabolism in response to
Samuel Hawgood, Francis R Poulain
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Pulmonary Surfactant and Respiratory Infections
Respiration, 1989The main data concerning the defensive role of pulmonary surfactant and respiratory infections are reported on the basis of recent knowledge on this topic. The opportunity to reintegrate the altered surfactant (in an exogenous way or by means of pharmacological agents) is also stressed.
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Metabolism of the apoproteins in pulmonary surfactant
Journal of Applied Physiology, 1977Two proteins having nominal molecular weights of 35,000 and 10,000 daltons are found in pulmonary surfactant. Although experiments on their immunological properties suggest that they share antigenic determinants, their metabolic relationship is unknown.
Richard J. King +3 more
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The Pulmonary Surfactant: Quantity and Quality
New England Journal of Medicine, 1979THE evolution of life from an aquatic to a gaseous environment necessitated the emergence of specialized organs for respiration characterized by large areas for gas exchange. In the mammalian lung, this surface area is provided by the repeated branching of the bronchial tree ending in respiratory units (alveoli) in which the epithelium is overlaid by a
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Pulmonary Surfactant in Health and Disease
Diseases of the Chest, 1965The airspaces of the lung may be compared to several hundred million bubbles blown on airways, and the surface tension necessary to prevent alveolar emptying can be estimated. If the alveolar surface were made of a transudate of plasma, we would expect the alveoli to be empty at the end of expiration.
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Hormonal Regulation of Pulmonary Surfactant
Endocrine Reviews, 1989I. Introduction THE LUNGS of mammals and many other vertebrates contain surface active material in the peripheral air spaces. This material, comprised of various lipids and proteins, gives rise to a phospholipid monolayer which lines lung alveoli. The lipid monolayer stabilizes alveoli at low lung volumes, preventing collapse and allowing for normal ...
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Surfactant in Pulmonary Oxygen Toxicity
1987Prolonged continuous exposure to high concentrations of oxygen can be lethal, due to respiratory failure. However, the cause of this respiratory failure is not known. The present study was designed to investigate the role of pulmonary surfactant in the development of respiratory failure induced by high concentrations of oxygen.
Jan Klein +4 more
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