Results 151 to 160 of about 592,819 (238)

Human Embryonic Stem Cell‐Derived Immunity‐And‐Matrix‐Regulatory Cells Attenuate Pulmonary Fibrosis via MMP1‐Mediated Collagen Degradation

Cell Proliferation, EarlyView.
Human embryonic stem cell‐derived Immunity‐and‐Matrix‐Regulatory Cells (IMRCs) effectively attenuate pulmonary fibrosis by secreting Matrix Metalloproteinase‐1 (MMP1), which directly degrades excess collagen I in the extracellular matrix. By directly degrading collagen I, IMRCs reverse ECM stiffness, suppress myofibroblast activation, and promote a ...
Zhongwen Li, Dingyun Song, Faguo Sun, Licheng Song, Bin An, Tingting Gao, Jingjing Liu, Kan Zhang, Kaidi Liu, Kaiwei Wu, Yajing Li, Yi Yang, Yaru Liu, Ruofan Su, Zai Wang, Tiemei Zhao, Huaiyong Chen, Li Xiao, Liang Peng, Liu Wang, Wei Li, Lixin Xie, Jie Hao, Huaping Dai, Jun Wu   +24 more
wiley   +1 more source

Progressive Pulmonary Alveolar Proteinosis Diagnosis Masking Pneumonic Lung Carcinoma: Anchoring Bias in Critical Care

Cytopathology, EarlyView.
A presumed case of pulmonary alveolar proteinosis with clinical deterioration was ultimately identified at autopsy as pneumonic‐type pleomorphic carcinoma. This case highlights the diagnostic overlap between diffuse lung diseases and the risk of anchoring bias in critically ill patients.
Dakota Wheeler, Rhaya Murray, Teklu Legesse, Hector Mesa   +3 more
wiley   +1 more source

Hypercapnia Induces Mitochondrial Adaptations and Alters Glutamine Metabolism to Drive a Distinct Metabolic Phenotype in Monocytes

Immunology &Cell Biology, EarlyView.
Elevated CO2 (hypercapnia) is a feature of serious lung diseases, for example COPD and contributes to poor patient prognosis through modulation of immune cell function. Here we employ state‐of‐the art metabolomic and isotope tracing approaches to reveal CO2‐dependent mitochondrial alterations linked to suppressed ATP, proline and glutamate levels in ...
Ben Reddan, David E. Phelan, Xiaofei Yin, Lorraine Brennan, Martina Wallace, Eoin P. Cummins   +5 more
wiley   +1 more source

Association Between Delivery Room Continuous Positive Airway Pressure and Neonatal Outcomes in Late Preterm and Term Infants: A Systematic Review and Meta‐Analysis

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Objective To explore the effects of delivery room continuous positive airway pressure (DR‐CPAP) in late preterm and term infants. Design Systematic review and meta‐analysis. Data Sources Cochrane Library, Embase, Emcare and MEDLINE were searched through March 26, 2025.
Yoxin Chin, Maclean Hill, Arun Sett, Niranjan Thomas, Abdul Razak   +4 more
wiley   +1 more source

Vasopressin Use in Extremely Preterm Infants With Refractory Cardiopulmonary Instability: Physiological Response and Mortality‐Associated Factors

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Objective To evaluate the physiological response following vasopressin initiation and identify factors associated with mortality in extremely preterm infants with refractory cardiopulmonary instability. Study Design Retrospective cohort study of infants born at less than 29 weeks' gestation who received vasopressin. Physiological responses and
Faisal Alamer, Kamal Ali, Saif Alsaif, Mohanned Alrahili, Mohammed Almahdi, Eman Bazbouz, Rana Almuqati, Saad Alshareedah, Faisal Alsehli, Abdulaziz Homedi   +9 more
wiley   +1 more source

Lung Ultrasound Practice in Australian and New Zealand Neonatal Intensive Care Units—A Survey

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Introduction Lung ultrasound (LUS) is increasingly used in neonatal intensive care units (NICUs) as a bedside, radiation‐free imaging tool for assessing respiratory conditions. Despite its advantages, data on current LUS practices in Australasian NICUs are limited. This study aimed to evaluate LUS use across NICUs in both countries.
V. Gruber, S. Morakeas, B. Schwaberger, M. B. Tracy   +3 more
wiley   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways

Journal of Periodontal Research, EarlyView.
This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru, Andreea C. Didilescu, Frank A. Scannapieco   +2 more
wiley   +1 more source

Phylogenetic Reconstruction of Lung Evolution in Extant Squamata

Journal of Zoology, EarlyView.
The Squamata group exhibits remarkable diversity in lung structure. However, a comprehensive understanding of how this variation evolved within the clade is still lacking. To reconstruct the evolutionary history of lungs of living squamates, we conducted comparative phylogenetic analyses using categorized lung traits, such as lung type, respiratory ...
Barbara de Godoi Champini, Ray Brasil Bueno de Souza, Wilfried Klein   +2 more
wiley   +1 more source

Eco‐Epidemiological Study of Seropositivity Against Rickettsia and Leptospira Agents in Rural Areas of Urabá, Colombia

Tropical Medicine &International Health, EarlyView.
ABSTRACT Introduction Rickettsioses and leptospirosis are infectious diseases often underdiagnosed due to limited knowledge about their epidemiology, pathophysiology, and clinical aspects. Objectives To characterize the seroprevalence and seroincidence of Rickettsia and Leptospira agents and determine their associated factors in rural areas of Urabá ...
Mariana Torres‐Bustamante, Omar Cantillo‐Barraza, Albert I. Ko, Elsio A. Wunder Jr, Juan C. Quintero‐Vélez   +4 more
wiley   +1 more source