Results 181 to 190 of about 647,511 (278)

Validation of the SPiRO Score for the Prediction of ICU Admission in Patients Presenting With Leptospirosis in Tropical Australia

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Objectives In some resource‐limited settings the case‐fatality rate of severe leptospirosis can exceed 50%. Early recognition of severe disease can expedite transfer to referral centres for advanced supportive care. The entirely clinical, 3‐point SPiRO score can be calculated rapidly at presentation to predict a patient's subsequent clinical ...
Patrick Rosengren   +10 more
wiley   +1 more source

Intestinal epithelial injury and inflammation after physical work in temperate and hot environments in older men with hypertension or type 2 diabetes

open access: yesExperimental Physiology, EarlyView.
Abstract We tested whether older adults with well‐controlled type 2 diabetes or hypertension, compared with age‐matched adults without chronic disease, exhibit greater intestinal damage, microbial translocation and inflammation during exertional heat stress.
Ben J. Lee   +8 more
wiley   +1 more source

Effect of foot immersion and neck cooling on renal, intestinal, immune and inflammatory markers in older adults exposed to extreme heat

open access: yesExperimental Physiology, EarlyView.
Abstract Older adults with reduced thermoregulatory capabilities are increasingly at risk of heat‐related pathophysiological outcomes (e.g., acute kidney injury, heatstroke) due to increasingly frequent, prolonged and intense heatwaves. Foot immersion and neck cooling have been proposed as practical, non‐electrical cooling strategies for protecting ...
Thomas McCarthy   +7 more
wiley   +1 more source

Impact of Aggregation on the Immunogenicity of Therapeutic Recombinant Biological Products. [PDF]

open access: yesPharmaceuticals (Basel)
Chen X   +8 more
europepmc   +1 more source

The efficacy and physiological bases of small muscle mass exercise in health and disease

open access: yesExperimental Physiology, EarlyView.
Abstract The conventional approach to aerobic exercise prescription involves large muscle mass exercise and the manipulation of variables such as training intensity, duration and frequency to promote desired adaptations. However, during whole‐body exercise, central limitations (i.e., neural, pulmonary and/or cardiac) constrain exercise tolerance and ...
Callum G. Brownstein
wiley   +1 more source

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