Results 11 to 20 of about 326,807 (261)

Text Mining-Based Drug Discovery for Connective Tissue Disease–Associated Pulmonary Arterial Hypertension

open access: yesFrontiers in Pharmacology, 2022
Background: The current medical treatments for connective tissue disease–associated pulmonary arterial hypertension (CTD-PAH) do not show favorable efficiency for all patients, and identification of novel drugs is desired.Methods: Text mining was ...
Jiang-Shan Tan   +4 more
doaj   +1 more source

Carbohydrate Antigen 125 Is a Biomarker of the Severity and Prognosis of Pulmonary Hypertension

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: Emerging evidence has showed that serum carbohydrate antigen 125 (CA 125) levels are associated with the severity and prognosis of heart failure. However, its role in pulmonary hypertension remains unclear. This study aimed to investigate the
Yi Zhang   +14 more
doaj   +1 more source

Creatine kinase is associated with bleeding after myocardial infarction

open access: yesOpen Heart, 2020
Background The ADP-scavenging enzyme creatine kinase (CK) is reported to reduce ADP-dependent platelet activation. Therefore, we studied whether highly elevated CK after ST-elevation myocardial infarction (STEMI) is associated with bleeding.Methods Data ...
Jesper Hastrup Svendsen   +4 more
doaj   +1 more source

Heart-Rate Recovery at 1 Min After Exercise Predicts Response to Balloon Pulmonary Angioplasty in Patients With Inoperable Chronic Thromboembolic Pulmonary Hypertension

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundDysfunction of autonomic nervous system plays an important role in the development of pulmonary hypertension. The present study aimed to investigate the interaction between balloon pulmonary angioplasty (BPA) and cardiac autonomic function by ...
Yi Zhang   +14 more
doaj   +1 more source

Cardiac magnetic resonance systematically overestimates mitral regurgitations by the indirect method

open access: yesOpen Heart, 2020
Objective Cardiac MRI is quickly emerging as the gold standard for assessment of mitral regurgitation, most commonly with the indirect method subtracting forward flow in aorta from volumetric segmentation of the left ventricle.
Jesper Hastrup Svendsen   +4 more
doaj   +1 more source

Cardiac ischemia and reperfusion in mice: a comprehensive hemodynamic, electrocardiographic and electrophysiological characterization

open access: yesScientific Reports, 2023
Malignant ventricular arrhythmias (VA) after acute myocardial infarction remain a major threat. Aim of this study was to characterize the electrophysiological and autonomic sequelae of cardiac ischemia and reperfusion (I/R) in mice during the first week ...
Lukas Clasen   +8 more
doaj   +1 more source

Clinical and Safety Outcomes Associated with Extended Treatment of Venous Thromboembolism: A Network Meta-Analysis

open access: yesJournal of Cardiovascular Development and Disease, 2022
Background: Many anticoagulant strategies are available for the extended treatment of venous thromboembolism, yet little guidance exists regarding which drug is most effective and safe.
Zhiqiang Liu   +4 more
doaj   +1 more source

Improved hemodynamics and cardiopulmonary function in patients with inoperable chronic thromboembolic pulmonary hypertension after balloon pulmonary angioplasty

open access: yesRespiratory Research, 2019
Background Balloon pulmonary angioplasty (BPA) has been demonstrated to improve cardiac function and exercise capacity in patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH), but its instant impact on cardiopulmonary function ...
Qi Jin   +12 more
doaj   +1 more source

Takotsubo syndrome with pulmonary embolism: a case report and literature review

open access: yesBMC Cardiovascular Disorders, 2018
Background Takotsubo syndrome (TTS) is an acute cardiac condition with reversible heart failure which is often triggered by psychological and physical stressful events.
Qi Jin   +7 more
doaj   +1 more source

Targeted therapy in pulmonary veno-occlusive disease: time for a rethink?

open access: yesBMC Pulmonary Medicine, 2019
Background Pulmonary veno-occlusive disease (PVOD) is a rare condition with poor prognosis, and lung transplantation is recommended as the only curative therapy.
Qin Luo   +8 more
doaj   +1 more source

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