Results 31 to 40 of about 326,807 (261)

Development and Validation of a Nomogram for Balloon Pulmonary Angioplasty-Related Complications in Patients with Chronic Thromboembolic Pulmonary Hypertension

Reviews in Cardiovascular Medicine, 2023
Background: Balloon pulmonary angioplasty (BPA)-related complications are not uncommon and could contribute to perioperative mortality. However, there is a lack of a prediction model for BPA-related complications.
Xin Li, Yi Zhang, Qi Jin, Qin Luo, Qing Zhao, Tao Yang, Qixian Zeng, Anqi Duan, Zhihua Huang, Meixi Hu, Sicheng Zhang, Luyang Gao, Changming Xiong, Zhihui Zhao, Zhihong Liu   +14 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Genetically Predicted Obesity Causally Increased the Risk of Hypertension Disorders in Pregnancy

Frontiers in Cardiovascular Medicine, 2022
AimsThis study aimed to evaluate the causal association between obesity and hypertension disorders in pregnancy.MethodsTwo-sample Mendelian randomization (MR) study was conducted based on the data obtained from the GIANT (n = 98,697 participants ...
Wenting Wang, Wenting Wang, Jiang-Shan Tan, Lu Hua, Shengsong Zhu, Hongyun Lin, Yan Wu, Jinping Liu   +7 more
doaj   +1 more source

Bile Pigments in Pulmonary and Vascular Disease [PDF]

Frontiers in Pharmacology, 2012
The bile pigments, biliverdin, and bilirubin, are endogenously derived substances generated during enzymatic heme degradation. These compounds have been shown to act as chemical antioxidants in vitro. Bilirubin formed in tissues circulates in the serum, prior to undergoing hepatic conjugation and biliary excretion.
openaire   +3 more sources

Pulmonary Vascular Diseases [PDF]

Circulation, 2008
The pulmonary circulation has fascinated researchers and clinicians for more than a century. Romberg first described the pathology of human pulmonary arterial hypertension (PAH) in 1891. In 1946, Euler and Liljestrand described the hypoxic pulmonary vasoconstriction: Whereas hypoxia dilates most systemic vascular beds, it constricts the pulmonary ...
Evangelos D. Michelakis, Hunter C. Champion   +1 more
openaire   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Comparing bridging drug therapy approaches prior to balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension: a prospective analysis from the national UK CURATE registry

Open Heart
Background Pulmonary hypertension (PH) medical therapies are commonly used as a bridge to balloon pulmonary angioplasty (BPA) in patients with chronic thromboembolic PH (CTEPH) but their effectiveness remains unclear.
Karen Sheares, Stephen P Hoole, John G Coghlan, John E Cannon, Dolores Taboada, Mark Toshner, Joanna Pepke-Zaba, Paul Bambrough, Hakim Ghani, Oliver M Li, Paula Appenzeller, Liliana Amaral-Almeida, Katherine L Bunclark   +12 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source

Serum human epididymis protein 4 level as a predictor of clinical worsening in idiopathic pulmonary arterial hypertension: a pilot study

BMC Cardiovascular Disorders, 2020
Background Human epididymis protein 4 (HE4) was proved to be a novel biomarker for left heart failure. The purpose of this exploratory study was to evaluate the role of HE4 in patients with idiopathic pulmonary arterial hypertension (IPAH) who usually ...
Qi Jin, Yi Tang, Zhihong Liu, Wenlin Xie, Qin Luo, Zhihui Zhao, Qing Zhao, Zhiwei Huang, Xue Yu, Lu Yan, Changming Xiong, Xinhai Ni, Yinkun Yan   +12 more
doaj   +1 more source