Results 151 to 160 of about 180,777 (427)

Atrial Fibrillation and the Autonomic Nervous System [PDF]

, 2012
Catheter ablation of atrial fibrillation (AF) has been increasingly employed as a therapeutic modality to maintain sinus rhythm. However, the procedure is potentially associated with major complications and its long-term efficacy is relatively poor. Thus,
Jackman, Warren M, Stavrakis, Stavros
core   +2 more sources

Improving procedural and one-year outcome after contact force-guided pulmonary vein isolation: the role of interlesion distance, ablation index, and contact force variability in the 'CLOSE'-protocol.

Europace, 2018
Aims We have recently shown that a contact force (CF)-guided ablation protocol respecting region-specific criteria of lesion contiguity and lesion depth ('CLOSE' protocol) is associated with high incidence of acute durable pulmonary vein (PV) isolation ...
T. Phlips, P. Taghji, M. El Haddad, M. Wolf, S. Knecht, Y. Vandekerckhove, R. Tavernier, M. Duytschaever   +7 more
semanticscholar   +1 more source

Wall thickness‐based adjustment of ablation index improves efficacy of pulmonary vein isolation in atrial fibrillation: Real‐time assessment by intracardiac echocardiography

Cardiovascular Electrophysiology, 2020
Ablation index (AI) linearly correlates with lesion depth and may yield better therapeutic performance in pulmonary vein isolation (PVI) when tailored to a patient's wall thickness (WT) in the left atrium (LA).
Yuji Motoike, Masahide Harada, Takehiro Ito, Y. Nomura, A. Nishimura, Masayuki Koshikawa, E. Watanabe, Y. Ozaki, H. Izawa   +8 more
semanticscholar   +1 more source

CircDNA2‐Educated YTHDF2 Phase Separation Promotes PM2.5‐Induced Malignant Transformation Through the Blunting of GADD45A Expression

Advanced Science, Volume 12, Issue 14, April 10, 2025.
This study unveiled the mechanism by which circDNA2‐educated YTHDF2 phase separation promotes PM2.5‐induced malignant transformation in HBE cells by blunting GADD45A expression, providing definitive evidence for the first time that LLPS is involved in the induction of tumorigenesis by particulate pollutants. Moreover, the clinical value of circDNA2 and
Jie Xu, Zhi Ling, Lijia Yin, Duo Xu, Shenshen Wu, Rui Chen   +5 more
wiley   +1 more source

Association of the left common ostium with clinical outcome after pulmonary vein isolation in atrial fibrillation

Indian Pacing and Electrophysiology Journal, 2021
Introduction: Electrical pulmonary vein isolation (PVI) is used for the invasive treatment of atrial fibrillation (AF). However, despite the procedure’s technical evolution, the rate of AF recurrence due to electrical reconnection of the PVs is high. The
Rafael M. Ronsoni, Tiago L. Silvestrini, Vidal Essebag, Renato D. Lopes, Marco Aurélio Lumertz Saffi, Tiago Luiz Luz Leiria   +5 more
doaj  

Morphing the left atrium geometry: The role of the pulmonary veins on flow patterns and thrombus formation [PDF]

Comput.Biol.Med.(2025),186:109612
Background: Despite the significant advances made in the field of computational fluid dynamics (CFD) to simulate the left atrium (LA) in atrial fibrillation (AF) conditions, the connection between atrial structure, flow dynamics, and blood stagnation in the left atrial appendage (LAA) remains unclear.
arxiv   +1 more source

Inhibition of RACK1‐Mediated NLRP3 Oligomerization (Active Conformation) Ameliorates Acute Respiratory Distress Syndrome

Advanced Science, EarlyView.
Schematic diagram showing the potential mechanism of bigelovin on the activation of NLRP3 inflammasome Bigelovin may inhibit activated protein C kinase 1 (RACK1) by directly binding with cys168 of RACK1. Bigelovin thus prevents oligomerization of NLRP3 (NLRP3 active conformation) and subsequent assembly of NLRP3 inflammasome, blocking the activation of
Jian Cui, Meng Yang, Chengli Yu, Haidong Zhang, Yuan Gong, Yang Hu, Yue Wang, Qingxin Yuan, An Pan, Jiepin Li, Yaowen Hu, Zecheng Jin, Xuemei Peng, Anyuan Wu, Junwei Wang, Qian Wang, Yinan Zhang, Lihong Hu   +17 more
wiley   +1 more source

Short tip–more function? Atrial fibrillation ablation using the novel third-generation cryoballoon in resected pulmonary vein

International Journal of Arrhythmia, 2019
Background Cryoballoon ablation is an established procedure for atrial fibrillation (AF). Patients who had previous pulmonary surgery undergoing pulmonary vein isolation (PVI) were seldom reported.
Shaojie Chen, Boris Schmidt, Stefano Bordignon, Fabrizio Bologna, K. R. Julian Chun   +4 more
doaj   +1 more source

PRMT1 Ablation in Endothelial Cells Causes Endothelial Dysfunction and Aggravates COPD Attributable to Dysregulated NF‐κB Signaling

Advanced Science, EarlyView.
This study investigates the role of protein arginine methyltransferase 1 (PRMT1) in endothelial cells (ECs) in chronic obstructive pulmonary disease (COPD). Mice with endothelial‐specific PRMT1 deletion develop pulmonary hemorrhage, inflammation, and apoptosis, driven by excessive nuclear factor kappa B activation.
Thi Thuy Vy Tran, Yideul Jeong, Suwoo Kim, Ji Eun Yeom, Jinwoo Lee, Wonhwa Lee, Gyu‐Un Bae, Jong‐Sun Kang   +7 more
wiley   +1 more source

Minimizing Exposure to Ionizing Radiation in Catheter-Based Treatment of Atrial Fibrillation: Safety and Efficacy

Український журнал серцево-судинної хірургії
Pulmonary vein isolation using radiofrequency ablation is the most common method of catheter treatment for atrial fibrillation. Performing this procedure involves the use of X-ray radiation, which at certain stages of the procedure is an indispensable ...
Є. О. Перепека, Б. Б. Кравчук, М. М. Cичик, С. Л. Миколайчук   +3 more
doaj   +1 more source