Results 41 to 50 of about 5,639 (136)

“Intrapericardial Approach” for Venous Outflow Reconstruction in Living‐Donor Liver Transplantation for Budd‐Chiari Syndrome: Surgical Techniques and LongTerm Outcomes

Annals of Gastroenterological Surgery, EarlyView.
Unlike deceased‐donor liver transplantation, living‐donor liver transplantation (LDLT) for Budd‐Chiari Syndrome (BCS) presents distinctive challenges in hepatic venous (HV)‐outflow reconstruction because diseased HV–inferior vena cava (IVC) cannot be entirely replaced with healthy donor vessels.
Koichiro Hata, Tetsuya Tajima, Satoshi Ogiso, Shinji Uemoto, Etsuro Hatano   +4 more
wiley   +1 more source

Pulmonary veno-occlusive disease in a patient with recently diagnosed systemic sclerosis

, 2019
Pulmonary veno-occlusive disease is a rare cause of pulmonary hypertension in patients with systemic sclerosis that can be misclassified as pulmonary arterial hypertension.
Vries-Bouwstra, J.K. de, Ninaber, M.K., Nossent, E., Ramiro, S., Leeuwen, N.M. van   +4 more
core   +1 more source

Pulmonary hypertension phenotypes in patients with systemic sclerosis

European Respiratory Review, 2021
Pulmonary hypertension (PH) commonly affects patients with systemic sclerosis (SSc) and is associated with significant morbidity and increased mortality.
Ashraful Haque, David G. Kiely, Gabor Kovacs, A.A. Roger Thompson, Robin Condliffe   +4 more
doaj   +1 more source

Clinical Impact of Maximum Plasma Concentration of Busulfan in Pediatric Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation

Clinical Pharmacology &Therapeutics, EarlyView.
Busulfan's narrow therapeutic index and high pharmacokinetic (PK) variability warrant investigation of its exposure–toxicity relationship. We retrospectively analyzed 334 pediatric and young adult patients who underwent allogeneic hematopoietic stem cell transplantation at Seoul National University Children's Hospital between 2009 and 2020 and received
Sungyeun Bae, Jung Yoon Choi, Kyung Taek Hong, Bo Kyung Kim, Hyun Jin Park, Kyung‐Sang Yu, Su‐jin Rhee, Hyoung Jin Kang   +7 more
wiley   +1 more source

First Successful Lung Transplantation for Sickle Cell Disease with Severe Pulmonary Arterial Hypertension and Pulmonary Veno‐Occlusive Disease [PDF]

, 2013
Little is known about the use of lung transplantation in the management of sickle cell disease-associated pulmonary arterial hypertension (SCD-PAH).
Maria M. Crespo, Syed Haider, Samuel A. Yousem, George, M Patricia, Shigemura, Norihisa, Feingold, Brian, Johnson, Bruce A, Matthew R. Morrell, Bruce A. Johnson, Toyoda, Yoshiya, Joseph M. Pilewski, Novelli, Enrico M, Krishnamurti, Lakshmanan, Gries, Cynthia G, Yoshiya Toyoda, Jay K. Bhama, Yousem, Samuel A, Enrico M. Novelli, Morrell, Matthew R, M. Patricia George, Bermudez, Christian, Hunter C. Champion, Pilewski, Joseph M, Brian Feingold, Lakshmanan Krishnamurti, Bhama, Jay K, Crespo, Maria M, Christian Bermudez, Mark T. Gladwin, Haider, Syed, Gladwin, Mark T, Marc A. Simon, Simon, Marc A, Champion, Hunter C, Norihisa Shigemura, Cynthia G. Gries   +35 more
core   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Pulmonary Hypertension Related to Left-Sided Cardiac Pathology

Pulmonary Medicine, 2011
Pulmonary hypertension (PH) is the end result of a variety of diverse pathologic processes. The chronic elevation in pulmonary artery pressure often leads to right ventricular pressure overload and subsequent right ventricular failure. In patients with
Todd L. Kiefer, Thomas M. Bashore
doaj   +1 more source

GCN2 in proteostasis: structural logic, signalling networks and disease

The FEBS Journal, EarlyView.
Threats to protein synthesis activate the kinase GCN2, initiating the integrated stress response (ISR). GCN2 is triggered by stalled ribosomes and uncharged tRNAs, which accumulate when amino acids are scarce. The ISR adjusts cellular physiology by promoting redox balance, protein quality control, and mitochondrial optimisation.
JiaYi Zhu, Stefan J. Marciniak
wiley   +1 more source

Pulmonary Veno-Occlusive Disease: A Newly Recognized Cause of Severe Pulmonary Hypertension in Dogs [PDF]

, 2016
Pulmonary hypertension is a well-known though poorly characterized disease in veterinary medicine. In humans, pulmonary veno-occlusive disease (PVOD) is a rare cause of severe pulmonary hypertension with a mean survival time of 2 years without lung ...
Jennings, S, Wilson, D, Cartoceti, A, Priestnall, S L, Williams, K, Jutkowitz, A, French, S, Goldsmith, D, Andrie, K   +8 more
core   +1 more source

A novel BMPR2 mutation with widely disparate heritable pulmonary arterial hypertension clinical phenotype

Pulmonary Circulation, 2020
Mutations in the gene encoding bone morphogenetic protein receptor type II ( BMPR2 ) have been associated with heritable pulmonary arterial hypertension (HPAH), whereas mutations in the gene encoding eukaryotic translation initiation factor 2 alpha ...
Ifeoma Oriaku, Mallory N. LeSieur, William C. Nichols, Roberto Barrios, C. Gregory Elliott, Adaani Frost   +5 more
doaj   +1 more source