Results 1 to 10 of about 24,712 (343)

Thymosin α1 alleviates pulpitis by inhibiting ferroptosis of dental pulp cells [PDF]

International Journal of Oral Science
Tooth pulpitis is a prevalent oral disorder. Understanding the underlying mechanisms of pulpitis and developing effective treatment strategies hold great significance.
Jie Wu, Qimei Gong, Wenxuan Liu, Aijia Chen, Zekai Liao, Yihua Huang, Wenkai Jiang, Zhongchun Tong   +7 more
doaj   +2 more sources

Identification of key module and hub genes in pulpitis using weighted gene co-expression network analysis [PDF]

BMC Oral Health, 2023
Background Pulpitis is a common disease mainly caused by bacteria. Conventional approaches of diagnosing the state of dental pulp are mainly based on clinical symptoms, thereby harbor deficiencies.
Denghui Zhang, Chen Zheng, Tianer Zhu, Fan Yang, Yiqun Zhou   +4 more
doaj   +2 more sources

PMAIP1 mediates endoplasmic reticulum stress in human dental pulp stem cells during pulpitis pathogenesis [PDF]

BMC Oral Health
Background Pulpitis, characterized by dental pulp inflammation, significantly impacts oral health, yet its molecular mechanisms remain poorly understood.
Caixia Zhou, Jiali Zhang, Luyi Chen, Yanheng Yu, Yingying Sun, Yunping Pan, Song Cai, Ping Zhong   +7 more
doaj   +2 more sources

Dysregulation of Pulpitis Progression Through Modulation of the lncRNA ITGB2-AS1 /miR-1224-5p Axis [PDF]

International Dental Journal
Introduction and aims: The onset of pulpitis is excruciatingly painful, and delayed treatment can lead to serious sequelae. LncRNAITGB2-AS1 is abnormally expressed in pulpitis samples, and thus, the present study was designed to investigate its ...
Jiabin Xu, Dongmei Lv, Changyong Yuan, Lina Huang   +3 more
doaj   +2 more sources

Role of necroptosis in pulpitis: integration of bacterial infection, immune imbalance, and oxidative stress [PDF]

PeerJ
Background Pulpitis is a common oral inflammatory condition driven by bacterial infection, immune imbalance, and oxidative stress, often involving pro-inflammatory cell death within the dental pulp.
Xuefei Wang, Yaying Wang, Zhenyu Pang, Peiyao Gong, Xuyi Ma, Yuhao Qiu, Jianzhen Li, Lianjie Peng, Zhichao Liu   +8 more
doaj   +3 more sources

Initial Insights into the NET-Associated ceRNA Network in Pulpitis: Transcriptomic and Functional Exploration [PDF]

International Dental Journal
Background: Pulpitis is an oral disease primarily triggered by microbial infections. Current therapeutic strategies lack specific agents targeting the underlying pathogenic mechanisms. Non-coding RNAs (ncRNAs) and their competitive endogenous RNA (ceRNA)
Xiaolan Guo, Kailun Wu, Longrui Dang, Sitong Liu, Jing Xu, Runting Wang, Junyang Xu, Yiming Zhong, Zhao Chen, Buling Wu   +9 more
doaj   +2 more sources

miR-455-3p is Involved in the Pathological Mechanism of Pulpitis by Modulating ACTG1 [PDF]

International Dental Journal
Background: Pulpitis is an inflammatory condition primarily induced by bacteria. The onset of pulpitis is typically accompanied by severe pain, which seriously affects the life quality of patients.
Yuejing Xu, Yihan Fu, Lei Zhang
doaj   +2 more sources

Differential Regulation of Angiogenesis, Lymphangiogenesis, and Neural Tissue in Normal and Inflamed Dental Pulp: Immunohistochemical Analysis [PDF]

Diagnostics
Background/Objectives: Pulp inflammation impairs healing, yet the underlying vascular and neural mechanisms remain poorly understood. This study investigated the differential regulation of lymphatic vessels, blood vessels, and neural tissue in pulpitis ...
Nooruldeen Ammar Alani, Bashar Hamid Abdullah   +1 more
doaj   +2 more sources

Assessment of correlation between clinical, radiographic, microbiological, and histopathological examinations in identification of pulpal diseases - a single-centre study

Saudi Dental Journal, 2023
Aim: This study aimed to analyse the presence of pulpitis using different techniques and compare the findings of the various examination methods. Methods: A total of 108 patients were enrolled and randomly divided into two groups: 56 patients whose pulp ...
Merita Barani, Xhevdet Aliu, Nexhmije Ajeti, Lumturije Asllani   +3 more
doaj   +1 more source

Identification and validation of m6A RNA regulatory network in pulpitis

BMC Oral Health, 2023
Background N6-methyladenosine (m6A) RNA modification regulators play an important role in many human diseases, and its abnormal expression can lead to the occurrence and development of diseases.
Hui Xu, Guangjin Chen, Jiaying Zhou, Xukang Zhou, Pengcheng Wang, Chunhui Chen, Zhi Xu, Fengyuan Lv, Xiaofang Li   +8 more
doaj   +1 more source