Results 31 to 40 of about 354 (138)

Effect of high‐intensity interval exercise on metformin pharmacokinetics in healthy men, assessed through a population pharmacokinetic model

British Journal of Pharmacology, Volume 183, Issue 3, Page 438-452, February 2026.
Abstract Background and Purpose Metformin and exercise are first‐line therapies for prediabetes and type 2 diabetes. However, it is unclear whether the combination of metformin and exercise is synergistic or antagonistic. The aim of this study was to investigate the effect of exercise on metformin pharmacokinetics and help clarify the contradictory ...
Stefanos Nikolaidis, Ioannis Kosmidis, Stylianos Papadopoulos, Artemis Lioupi, Marita Gandanidou, Helen Gika, Aristides Dokoumetzidis, Georgios Theodoridis, Vassilis Mougios   +8 more
wiley   +1 more source

A Bayesian method for pulsar template generation [PDF]

Monthly Notices of the Royal Astronomical Society, 2015
Extracting Times of Arrival from pulsar radio signals depends on the knowledge of the pulsars pulse profile and how this template is generated. We examine pulsar template generation with Bayesian methods. We will contrast the classical generation mechanism of averaging intensity profiles with a new approach based on Bayesian inference. We introduce the
Imgrund, M., Champion, D., Kramer, M., Lesch, H.   +3 more
openaire   +3 more sources

Single‐Position Peptide Clustering for Peptidomics Reveals Novel Disease Biomarkers and Dysregulated Proteolytic Characteristics

Advanced Science, Volume 13, Issue 5, 27 January 2026.
A novel amino acid (aa)‐score‐based single‐position peptide clustering strategy is developed for peptidomics, enabling precise profiling of protein proteolysis in plasma from β‐thalassemia cohort. The method identifies new aa position‐based peptide cluster biomarkers validated by heavy‐labeled peptides, visualizes aggregated changes, uncovers disease ...
Na Li, Yaxin Zhu, Yumeng Yan, Jifeng Wang, Lili Niu, Xiang Ding, Mengmeng Zhang, Zhensheng Xie, Tanxi Cai, Xiaojing Guo, Jianming Luo, Peng An, Xiangqian Guo, Fuquan Yang   +13 more
wiley   +1 more source

Multi‐scale maternal behavioral responses by white‐tailed deer to coyote predation risk

The Journal of Wildlife Management, Volume 90, Issue 1, January 2026.
In the piedmont region of the southeastern US, white‐tailed deer adjust maternal care strategies in response to variation in risk of encountering coyotes. In areas frequented by coyotes, adult female deer (i.e., does) increase their use of space, likely to avoid drawing coyotes to the location where a fawn is hidden.
Michael S. Muthersbaugh, Wesley W. Boone, Elizabeth A. Saldo, Alex J. Jensen, Charles Ruth, Jay Cantrell, John C. Kilgo, David S. Jachowski   +7 more
wiley   +1 more source

Cherenkov Telescope Array Observatory: Die Zukunft der Gammaastronomie

Physik in unserer Zeit, Volume 57, Issue 1, Page 10-18, January 2026.
Im Jahr 1989 hat das Wipple‐Observatorium die erste Quelle hochenergetischer Gammastrahlung entdeckt. 2002 waren dann sechs Quellen bekannt, 2024 schon mehr als 300. Und das ist immer noch lediglich die Spitze des Eisbergs in der jungen Geschichte der Gammaastronomie.
Daniela Hadasch, Daniel Mazin
wiley   +1 more source

Leveraging Compressed Sensing and Radiomics for Robust Feature Selection for Outcome Prediction in Personalized Ultra‐Fractionated Stereotactic Adaptive Radiotherapy

Advanced Intelligent Systems, Volume 7, Issue 12, December 2025.
A compressed sensing (CS)‐based feature selection method is proposed to select the most informative elements in the radiomic features extracted from medical images of personalized ultra‐fractionated stereotactic adaptive treatment. The CS‐based approach is able to simplify the feature selection process and enhance the accuracy and robustness of a ...
Yajun Yu, Steve Jiang, Robert Timmerman, Hao Peng   +3 more
wiley   +1 more source

Pulsar candidate classification using generative adversary networks

Monthly Notices of the Royal Astronomical Society, 2019
ABSTRACT Discovering pulsars is a significant and meaningful research topic in the field of radio astronomy. With the advent of astronomical instruments, the volume and rate of data acquisition have grown exponentially. This development necessitates a focus on artificial intelligence (AI) technologies that can mine large astronomical ...
Ping Guo, Fuqing Duan, Pei Wang, Yao Yao, Qian Yin, Xin Xin, Di Li, Lei Qian, Shen Wang, Zhichen Pan, Lei Zhang   +10 more
openaire   +1 more source

Improving pulsar search efficiency in next-generation pulsar surveys with artificial intelligence

Monthly Notices of the Royal Astronomical Society
Abstract Pulsar searching with next-generation radio telescopes requires efficiently sifting through millions of candidates generated by search pipelines to identify the most promising ones. This challenge has motivated the utilization of Artificial Intelligence (AI)-based tools.
Qiuyang Fu, Mengyao Xue, Weiwei Zhu, N D R Bhat, Kaichao Wu, Zihan Zhang, B W Meyers, Chia Min Tan, Youling Yue, Jiarui Niu, Lingqi Meng, Ziwei Wu, Ziyao Fang, Yukai Zhou, Jiawei Jin   +14 more
openaire   +2 more sources

Binary pulsars and tests of general relativity [PDF]

Proceedings of the International Astronomical Union, 2009
AbstractBinary pulsars are a valuable laboratory for gravitational experiments. Double-neutron-star systems such as the double pulsar provide the most stringent tests of strong-field gravity available to date, while pulsars with white-dwarf companions constrain departures from general relativity based on the difference in gravitational binding energies
openaire   +1 more source

Cracking the Endothelial Calcium (Ca²⁺) Code: A Matter of Timing and Spacing. [PDF]

Int J Mol Sci, 2023
Moccia F, Brunetti V, Soda T, Berra-Romani R, Scarpellino G.   +4 more
europepmc   +1 more source