Results 41 to 50 of about 3,415,425 (290)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Biomimetics, 2023 Micro-electro-mechanical system (MEMS) pressure sensors play a significant role in pulse wave acquisition. However, existing MEMS pulse pressure sensors bound with a flexible substrate by gold wire are vulnerable to crush fractures, leading to sensor ...
Xiaoxiao Kang +8 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Frontiers in Endocrinology, 2017 BackgroundThe association of pulse pressure and peripheral arterial disease (PAD) has seldom been examined using a prospective design. This study aimed to investigate the association of pulse pressure with PAD incidence in an elderly general population ...
Yong Mao +6 more
doaj +1 more source
Sensors, 2020 The measurement and analysis of the arterial pulse wave provides information about the state of vascular health. When measuring blood pressure according to Riva-Rocci, the systolic and diastolic blood pressure is measured non-invasively with an ...
Horst Hellbrück +3 more
doaj +1 more source
Blood Pressure Estimation by Photoplethysmogram Decomposition into Hyperbolic Secant Waves
Applied Sciences, 2022 Photoplethysmographic (PPG) pulses contain information about cardiovascular parameters. In particular, blood pressure can be estimated using PPG pulse decomposition analysis, which assumes that a PPG pulse is composed of the original heart ejection blood
Takumi Nagasawa +7 more
doaj +1 more source
Elevated pulse pressure during the acute period of ischemic stroke is associated with poor stroke outcome [PDF]
, 2004 <p><b>Background:</b> It is controversial which component of blood pressure (BP) during acute period of stroke best predicts outcome.
Lees, K.R. +6 more
core +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Pulse pressure and arterial elasticity [PDF]
QJM, 2002 The last decade has seen increased interest in the mechanical interaction between the heart and the arterial system. In particular, it has been suggested that increased arterial stiffness is associated with the development of cardiovascular disease and may even predict its development at an early stage before vascular lesions or external symptoms ...
openaire +2 more sources
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source