Results 41 to 50 of about 364,615 (261)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Relationship of Ocular Pulse Amplitude with Eye Structures and Systemic Blood Pressure
Türk Oftalmoloji Dergisi, 2011 Pur po se: To assess the relationship of ocular pulse amplitude with eye structures and systemic blood pressure in healthy subjects. Ma te ri al and Met hod: Fifty-one healthy subjects were included in the study.
Ebru Nevin Çetin +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Field mapping of ballistic pressure pulse sources
Current Directions in Biomedical Engineering, 2015 Ballistic pressure pulse sources are used since late 1990s for the extracorporeal treatment of chronic Enthesitis. Newly indications are found in trigger-point-therapy for the treatment of musculoskeletal disorders. In both applications excellent results
Rad Abtin Jamshidi, Ueberle Friedrich
doaj +1 more source
Cuffless Blood Pressure Estimation Using Pressure Pulse Wave Signals
Sensors, 2018 Pulse transit time (PTT) has received considerable attention for noninvasive cuffless blood pressure measurement. However, this approach is inconvenient to deploy in wearable devices because two sensors are required for collecting two-channel ...
Zeng-Ding Liu +5 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
2.2 TRANSFER FUNCTION-DERIVED CENTRAL PRESSURE AND CARDIOVASCULAR EVENTS: THE FRAMINGHAM HEART STUDY
Artery Research, 2013 Relations between central versus brachial blood pressure and major cardiovascular disease (CVD) events remain controversial. Central measures derived using radial tonometry and a generalized transfer function as implemented using the SphygmoCor device ...
G.F. Mitchell +7 more
doaj +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Jornal de Pediatria, 2022 Objective: In this study, the authors aimed to evaluate the effectiveness of the vena cava distensibility index and pulse pressure variation as dynamic parameters for estimating intravascular volume in critically ill children.
Başak Akyıldız, Serkan Özsoylu
doaj +1 more source
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source