Results 61 to 70 of about 6,861,533 (339)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Brachialis Pulse Wave Measurements with Ultra-Wide Band and Continuous Wave Radar, Photoplethysmography and Ultrasonic Doppler Sensors

open access: yesSensors, 2020
The measurement and analysis of the arterial pulse wave provides information about the state of vascular health. When measuring blood pressure according to Riva-Rocci, the systolic and diastolic blood pressure is measured non-invasively with an ...
Horst Hellbrück   +3 more
doaj   +1 more source

Method and apparatus for continuously monitoring blood oxygenation, blood pressure, pulse rate and the pressure pulse curve utilizing an ear oximeter as transducer Patent [PDF]

open access: yes, 1968
Ear oximeter for monitoring blood oxygenation and pressure, pulse rate, and pressure pulse curve, using dc and ac ...
Smith, J. R., Jr.
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Comparison of vena cava distensibility index and pulse pressure variation for the evaluation of intravascular volume in critically ill children

open access: yesJornal de Pediatria, 2022
Objective: In this study, the authors aimed to evaluate the effectiveness of the vena cava distensibility index and pulse pressure variation as dynamic parameters for estimating intravascular volume in critically ill children.
Başak Akyıldız, Serkan Özsoylu
doaj   +1 more source

Pulse pressure and perioperative stroke [PDF]

open access: yesCurrent Opinion in Anaesthesiology, 2019
Central pulse pressure (PP), a marker of vascular stiffness, is a novel indicator of risk for perioperative morbidity including ischemic stroke. Appreciation for the mechanism by which vascular stiffness leads to organ dysfunction along with understanding its clinical detection may lead to improved patient management.Vascular stiffness is associated ...
Abbas, Al-Qamari   +3 more
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Field mapping of ballistic pressure pulse sources

open access: yesCurrent Directions in Biomedical Engineering, 2015
Ballistic pressure pulse sources are used since late 1990s for the extracorporeal treatment of chronic Enthesitis. Newly indications are found in trigger-point-therapy for the treatment of musculoskeletal disorders. In both applications excellent results
Rad Abtin Jamshidi, Ueberle Friedrich
doaj   +1 more source

Cuffless Blood Pressure Estimation Using Pressure Pulse Wave Signals

open access: yesSensors, 2018
Pulse transit time (PTT) has received considerable attention for noninvasive cuffless blood pressure measurement. However, this approach is inconvenient to deploy in wearable devices because two sensors are required for collecting two-channel ...
Zeng-Ding Liu   +5 more
doaj   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri   +7 more
wiley   +1 more source

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