Results 51 to 60 of about 925,843 (350)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
An ultrasonic approach for contact stress mapping in machine joints and concentrated contacts [PDF]
, 2004 The measurement of pressure at a contact in a machine part is important because contact stresses frequently lead to failure by seizure, wear or fatigue.
Drinkwater, B.W. +3 more
core +1 more source
Pulse pressure and perioperative stroke [PDF]
Current Opinion in Anaesthesiology, 2019 Central pulse pressure (PP), a marker of vascular stiffness, is a novel indicator of risk for perioperative morbidity including ischemic stroke. Appreciation for the mechanism by which vascular stiffness leads to organ dysfunction along with understanding its clinical detection may lead to improved patient management.Vascular stiffness is associated ...
Abbas, Al-Qamari +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Arterial pulse wave pressure transducer [PDF]
, 1974 An arterial pulse wave pressure transducer is introduced. The transducer is comprised of a fluid filled cavity having a flexible membrane disposed over the cavity and adapted to be placed on the skin over an artery.
Chen, W., Gorelick, D., Kim, C.
core +1 more source
Field mapping of ballistic pressure pulse sources
Current Directions in Biomedical Engineering, 2015 Ballistic pressure pulse sources are used since late 1990s for the extracorporeal treatment of chronic Enthesitis. Newly indications are found in trigger-point-therapy for the treatment of musculoskeletal disorders. In both applications excellent results
Rad Abtin Jamshidi, Ueberle Friedrich
doaj +1 more source
2.2 TRANSFER FUNCTION-DERIVED CENTRAL PRESSURE AND CARDIOVASCULAR EVENTS: THE FRAMINGHAM HEART STUDY
Artery Research, 2013 Relations between central versus brachial blood pressure and major cardiovascular disease (CVD) events remain controversial. Central measures derived using radial tonometry and a generalized transfer function as implemented using the SphygmoCor device ...
G.F. Mitchell +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Droplet deformation by short laser-induced pressure pulses [PDF]
, 2017 When a free-falling liquid droplet is hit by a laser it experiences a strong ablation driven pressure pulse. Here we study the resulting droplet deformation in the regime where the ablation pressure duration is short, i.e. comparable to the time scale on
Gelderblom, Hanneke +2 more
core +4 more sources
Relationship of Ocular Pulse Amplitude with Eye Structures and Systemic Blood Pressure
Türk Oftalmoloji Dergisi, 2011 Pur po se: To assess the relationship of ocular pulse amplitude with eye structures and systemic blood pressure in healthy subjects. Ma te ri al and Met hod: Fifty-one healthy subjects were included in the study.
Ebru Nevin Çetin +4 more
doaj +1 more source