Results 21 to 30 of about 283,717 (266)

PULSE GLUCOCORTICOIDS

open access: yesDermatologic Clinics, 2000
High-dose intravenous (i.v.) methylprednisolone has been used therapeutically in a number of medical fields to avoid the complications and side effects of long-term glucocorticoid (GC) therapy and because of the perception that high-dose i.v. methylprednisolone may have "special" therapeutic effects.
S, Sabir, V P, Werth
openaire   +2 more sources

Identification of best housekeeping gene for normalization in qRT-PCR data under different development stages and stress conditions in Vigna mungo

open access: yesScientific Reports
The qRT-PCR has emerged as the most sought-after local gene expression profiling technique. The absolute quantification of the mRNA is highly affected by the handling artifacts.
Sudhir Kumar Jha   +10 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

A comprehensive review on grain legumes as climate‐smart crops: Challenges and prospects

open access: yesEnvironmental Challenges, 2022
Global food production needs to be doubled by 50% by the middle of 21st century to ensure the food and nutritional security for 9 billion people explicitly in the challenging scenarios such as land degradation, water scarcity and environmental pollution.
Asik Dutta   +4 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Biological characterization and variability of the nucleocapsid protein gene of Groundnut bud necrosis virus isolates infecting pea from India

open access: yesPhytopathologia Mediterranea, 2012
A disease of pea characterized by browning in veins, leaves and stems, mostly in growing tips, and brown circular spots on pods, was recorded in four districts of Uttar Pradesh, India.
Mohammad AKRAM, NAIMUDDIN
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Characterisation of the α-GOS profile of field pea and cowpea cultivars and their modulation through sustainable processing methods

open access: yesFrontiers in Sustainable Food Systems
α-galactooligosaccharides (α-GOS) are a class of non-nutritional compounds present in pulses. These carbohydrates are associated with irritable bowel syndrome (IBS).
Kalpana Tewari   +10 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Identification of stable resistant wild pigeonpea donors to multiple predominant bruchid species in India

open access: yesScientific Reports
Identifying stable-resistant sources offers an eco-friendly and sustainable insect management strategy. Sixty-eight wild pigeonpea accessions were systematically screened against three predominant bruchid species (Callosobruchus analis, C.
Revanasidda Aidbhavi   +10 more
doaj   +1 more source

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