Results 51 to 60 of about 967,429 (300)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Propagation and interaction of ultrashort electromagnetic pulses in nonlinear media with a quadratic-cubic nonlinearity

open access: yes, 2000
Propagation of extremely short unipolar pulses of electromagnetic field ("videopulses") is considered in the framework of a model in which the material medium is represented by anharmonic oscillators (approximating bound electrons) with quadratic and ...
Akimoto   +23 more
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Logic circuit detects both present and missing negative pulses in superimposed wave trains [PDF]

open access: yes, 1967
Pulse divide and determination network provides a logical determination of pulse presence within a data train. The network uses digital logic circuitry to divide positive and negative pulses, to shape the separated pulses, and to determine, by means of ...
Rice, R. E.
core   +1 more source

Coherent control using adaptive learning algorithms

open access: yes, 2001
We have constructed an automated learning apparatus to control quantum systems. By directing intense shaped ultrafast laser pulses into a variety of samples and using a measurement of the system as a feedback signal, we are able to reshape the laser ...
A. Assion   +32 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Influence of legume diversification and fertilization on soil potassium pools under distinct cropping system ecologies: insight from 14-years study

open access: yesFrontiers in Sustainable Food Systems
Sustaining levels of soil potassium (K) pools in soils across agro-ecologies are crucial for optimizing nutrient use, prevent K depletion, and ensure long-term soil health.
Chaitanya Prasad Nath   +7 more
doaj   +1 more source

Multifrequency Observations of Giant Radio Pulses from the Millisecond Pulsar B1937+21

open access: yes, 1999
Giant pulses are short, intense outbursts of radio emission with a power-law intensity distribution that have been observed from the Crab Pulsar and PSR B1937+21.
A. Kinkhabwala   +3 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

High Order Coherent Control Sequences of Finite-Width Pulses

open access: yes, 2011
The performance of sequences of designed pulses of finite length $\tau$ is analyzed for a bath of spins and it is compared with that of sequences of ideal, instantaneous pulses.
Biercuk M. J.   +12 more
core   +1 more source

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