A microRNA CRISPR screen reveals microRNA-483-3p as an apoptotic regulator in prostate cancer cells. [PDF]
Chow JT +9 more
europepmc +1 more source
Summary Small nucleolar ribonucleic acids (snoRNAs) are a class of small non‐coding RNAs involved in the post‐transcriptional modification of ribosomal RNAs (rRNA) and small nuclear RNAs (snRNA). Mounting evidence indicates that specific snoRNAs are drivers of oncogenesis, but their role in B‐cell precursor acute lymphoblastic leukaemia (BCP‐ALL) is ...
Martijn W. C. Verbeek +13 more
wiley +1 more source
Antiproliferative and Pro-Apoptotic Effects of <i>Tuber borchii</i> Extracts on Human Colorectal Cancer Cells via p53-Dependent Pathway Activation. [PDF]
Carinci E +8 more
europepmc +1 more source
We report the first confirmed record of an ocelot (Leopardus pardalis) dragging a newborn calf in a degraded forest fragment of southeastern Brazil. Using camera trap records, we reveal an opportunistic foraging event involving a vulnerable domestic prey within a highly fragmented landscape.
Álvaro Augusto Naves Silva +2 more
wiley +1 more source
PuMA: PubMed gene/cell type-relation Atlas. [PDF]
Bickmann L +3 more
europepmc +1 more source
Animal–Plant Interactions Under Defaunation: Consequences for Amazonian Trees of Commercial Interest
We experimentally investigated the effects of medium‐ and large‐sized mammal defaunation on the removal and fate of seeds from economically important forest species in Amazonian forests. Our results show that mammal exclusion significantly reduced seed removal, although the magnitude of this effect varied among plant species.
Arlison Castro +5 more
wiley +1 more source
PatchWorkPlot: simultaneous visualization of local alignments across multiple sequences. [PDF]
Pospelova M, Safonova Y.
europepmc +1 more source
LMPt enters the cell mainly through caveolin‐mediated endocytosis, and then fuses with endosomes and lysosomes to deliver MPt to mitochondria and the endoplasmic reticulum to induce mitophagy based on the fusion of lysosomes and mitochondria, and endoplasmic reticulum stress and subsequent apoptosis via the Bip–PERK–eIF2α–ATF4 axis to exert an anti ...
Cong Zhao +9 more
wiley +1 more source
Editorial Expression of Concern: p53's mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity. [PDF]
Wolff S, Erster S, Palacios G, Moll UM.
europepmc +1 more source
No Pedigree, No Problem: Genomic Inbreeding Tracks Genetic Rescue With High Resolution
ABSTRACT With increasing habitat fragmentation and population isolation, inbreeding becomes a pressing concern for the persistence of wildlife populations. Detailed inbreeding monitoring is crucial for assessing extinction risk and evaluating the effectiveness of conservation management strategies.
Carson Mitchell +4 more
wiley +1 more source

